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Reference Report
| Reference | |||
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| Citation | Shuai, Y., Zhang, Y., Gao, L., Zhong, Y. (2011). Stress Resistance Conferred by Neuronal Expression of Dominant-Negative Rac in Adult Drosophila melanogaster. J. Neurogenet. 25(1-2): 35--39. (Export to RIS) | ||
| FlyBase ID | FBrf0213665 | ||
| Publication Type | Research paper | ||
| PubMed ID | 21563892 | ||
| PubMed Abstract | How does brain coordinate physiological and behavioral responses to achieve survival in adverse environment is intriguing yet complicated. During studies of the small G protein Rac's role in learning and memory, the authors unexpectedly observed that neuronal expression of dominant-negative Rac in adult Drosophila remarkably enhanced the survival of animals in various stress conditions, including oxidation, desiccation, starvation, and heat. The elevated stress resistance was not accompanied by a reduction in female fecundity or a change in whole-body lipid storage. The observation therefore implies the involvement of small G protein Rac in neuronal regulation of global stress responses. | ||
| DOI | 10.3109/01677063.2011.573891 | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | J. Neurogenet. | ||
| Title | Journal of Neurogenetics | ||
| Publication Year | 1983- | ||
| ISBN/ISSN | 0167-7063 | ||
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Data from Reference
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| Alleles (6)
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| Constructs (4)
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| Genes (3)
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| Insertions (2)
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