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Tan, D.J., Dvinge, H., Christoforou, A., Bertone, P., Martinez Arias, A., Lilley, K.S. (2009). Mapping organelle proteins and protein complexes in Drosophila melanogaster.  J. Proteome Res. 8(6): 2667--2678.
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FBrf0215446
Publication Type
Research paper
Abstract
Many proteins within eukaryotic cells are organized spatially and functionally into membrane bound organelles and complexes. A protein's location thus provides information about its function. Here, we apply LOPIT, a mass-spectrometry based technique that simultaneously maps proteins to specific subcellular compartments, to Drosophila embryos. We determine the subcellular distribution of hundreds of proteins, and protein complexes. Our results reveal the potential of LOPIT to provide average snapshots of cells.
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    J. Proteome Res.
    Title
    Journal of Proteome Research
    Publication Year
    2002
    ISBN/ISSN
    1535-3893
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