Reference Report

Reference
Citation	Plyusnina, E.N., Shaposhnikov, M.V., Moskalev, A.A. (2012). Geroprotective Effects of Activation of D-GADD45 DNA Reparation Gene in Drosophila Melanogaster Nervous System. Bull. Exp. Biol. Med. 152(3): 340--343. (Export to RIS)
FlyBase ID	FBrf0218915
Publication Type	Research paper
PubMed ID	22803081
PubMed Abstract	The expression of D-GADD45 gene involved in DNA reparation in Drosophila melanogaster decreases with age. Overexpression of D-GADD45 in the drosophila nervous system prolongs the median and maximum life span without deterioration of the quality of life parameters (fertility and neuromuscular activity). The life span prolongation effect is due to more effective DNA reparation, as spontaneous level of DNA aberrations in the nerve tissue of larvae with D-GADD45 overexpression is reduced significantly.
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Language of Publication	English
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Parent Publication
Publication Type	Journal
Abbreviation	Bull. Exp. Biol. Med.
Title	Bulletin of experimental biology and medicine [English translation edition of Biulleten' Eksperimental'noi Biologii i Meditsiny]
Publication Year	1956-
ISBN/ISSN	0007-4888
Data from Reference
Genes (1)
	Gadd45