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Citation
Menon, D.U., Meller, V.H. (2012). A Role for siRNA in X-Chromosome Dosage Compensation in Drosophila melanogaster.  Genetics 191(3): 1023--1028.
FlyBase ID
FBrf0218921
Publication Type
Research paper
Abstract

Sex-chromosome dosage compensation requires selective identification of X chromatin. How this occurs is not fully understood. We show that small interfering RNA (siRNA) mutations enhance the lethality of Drosophila males deficient in X recognition and partially rescue females that inappropriately dosage-compensate. Our findings are consistent with a role for siRNA in selective recognition of X chromatin.

PubMed ID
PubMed Central ID
PMC3389965 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Genetics
    Title
    Genetics
    Publication Year
    1916-
    ISBN/ISSN
    0016-6731
    Data From Reference
    Aberrations (1)
    Alleles (14)
    Genes (17)
    Insertions (2)
    Transgenic Constructs (1)