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Citation
Andersen, D.S., Colombani, J., Léopold, P. (2013). Coordination of organ growth: principles and outstanding questions from the world of insects.  Trends Cell Biol. 23(7): 336--344.
FlyBase ID
FBrf0221962
Publication Type
Review
Abstract

In animal species undergoing determinate growth, the making of a full-size adult body requires a series of coordinated growth events culminating in the cessation of growth that precedes sexual maturation. The merger between physiology and genetics now coming to pass in the Drosophila model allows us to decipher these growth events with an unsurpassed level of sophistication. Here, we review several coordination mechanisms that represent fundamental aspects of growth control: adaptation of growth to environmental cues, interorgan coordination, and the coordination of growth with developmental transitions. The view is emerging of an integrated process where organ-autonomous growth is coordinated with both developmental and environmental cues to define final body size.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Trends Cell Biol.
    Title
    Trends in Cell Biology
    Publication Year
    1991-
    ISBN/ISSN
    0962-8924
    Data From Reference