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Citation
Robinson, B.G., Atkinson, N.S. (2013). Is alcoholism learned? Insights from the fruit fly.  Curr. Opin. Neurobiol. 23(4): 529--534.
FlyBase ID
FBrf0222263
Publication Type
Review
Abstract
Alcohol addiction is a complex, unique human disease. Breaking addiction down into contributing endophenotypes enables its study in a variety of model systems. The Drosophila model system has been most often used to study alcohol sensitivity, tolerance, and physiological dependence. However, none of these endophenotypes can account for the near-permanent quality of the addicted state. It has been recently discussed that addictive drugs may hijack the learning-and-memory machinery to produce persistent behavioral changes. Learning and memory is amenable to experimental study, and provides us with a window into how alcohol affects higher-order mental functions that are likely to contribute compulsive drug use. Here, we review the Drosophila literature that links alcohol-related behaviors to learning and memory.
PubMed ID
PubMed Central ID
PMC4586068 (PMC) (EuropePMC)
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Opin. Neurobiol.
    Title
    Current Opinion in Neurobiology
    Publication Year
    1991-
    ISBN/ISSN
    0959-4388
    Data From Reference