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Moussian, B. (2013). The apical plasma membrane of chitin-synthesizing epithelia.  Insect Sci. 20(2): 139--146.
FlyBase ID
FBrf0222425
Publication Type
Review
Abstract

Abstract  Chitin is the second most abundant polysaccharide on earth. It is produced at the apical side of epidermal, tracheal, fore-, and hindgut epithelial cells in insects as a central component of the protective and supporting extracellular cuticle. Chitin is also an important constituent of the midgut peritrophic matrix that encases the food supporting its digestion and protects the epithelium against invasion by possibly ingested pathogens. The enzyme producing chitin is a glycosyltransferase that resides in the apical plasma membrane forming a pore to extrude the chains of chitin into the extracellular space. The apical plasma membrane is not only a platform for chitin synthases but, probably through its shape and equipment with distinct factors, also plays an important role in orienting and organizing chitin fibers. Here, I review findings on the cellular and molecular constitution of the apical plasma membrane of chitin-producing epithelia mainly focusing on work done in the fruit fly Drosophila melanogaster.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Insect Sci.
    Title
    Insect Science
    Publication Year
    2005-
    ISBN/ISSN
    1744-7917 1672-9609
    Data From Reference
    Genes (11)