Open Close
Reference
Citation
Zeidler, M.P., Bausek, N. (2013). The Drosophila JAK-STAT pathway.  JAKSTAT 2(3): e25353.
FlyBase ID
FBrf0222849
Publication Type
Review
Abstract

The conservation of signaling cascades between humans and Drosophila, over more than 500 million years of evolutionary time, means that the genetic tractability of the fly can be used to its full advantage to understand the functional requirements for JAK-STAT pathway signaling across species. Here we review the background to how the pathway was first identified and the first characterization of JAK-STAT pathway phenotypes in the Drosophila system, highlighting the molecular, functional, and disease-related conservation of the pathway.

PubMed ID
PubMed Central ID
PMC3772116 (PMC) (EuropePMC)
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    JAKSTAT
    Title
    JAK-STAT
    ISBN/ISSN
    2162-3988 2162-3996
    Data From Reference
    Gene Groups (1)
    Genes (15)