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Citation
Gelman, A., Rawet-Slobodkin, M., Elazar, Z. (2015). Huntingtin facilitates selective autophagy.  Nat. Cell Biol. 17(3): 214--215.
FlyBase ID
FBrf0228256
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Note
Abstract

Selective autophagy is essential for maintaining cellular homeostasis under different growth conditions. Huntingtin, mutated versions of which have been implicated in Huntington disease, is now shown to act as a scaffold protein that couples the induction of autophagy and the selective recruitment of cargo into autophagosomes.

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Related Publication(s)
Research paper

Huntingtin functions as a scaffold for selective macroautophagy.
Rui et al., 2015, Nat. Cell Biol. 17(3): 262--275 [FBrf0227668]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nat. Cell Biol.
    Title
    Nature Cell Biology
    Publication Year
    1999-
    ISBN/ISSN
    1465-7392 1476-4679
    Data From Reference