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Citation
Denton, D., Kumar, S. (2015). Studying Apoptosis in Drosophila.  Cold Spring Harb. Protoc. 2015(7): pdb.top070433.
FlyBase ID
FBrf0228864
Publication Type
Review
Abstract
The apoptotic machinery is highly conserved throughout evolution, and central to the regulation of apoptosis is the caspase family of cysteine proteases. Insights into the regulation and function of apoptosis in mammals have come from studies using model organisms. Drosophila provides an exceptional model system for identifying the function of conserved mechanisms regulating apoptosis, especially during development. The characteristic patterns of apoptosis during Drosophila development have been well described, as has the apoptotic response following DNA damage. The focus of this discussion is to introduce methodologies for monitoring apoptosis during Drosophila development and also in Drosophila cell lines.
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cold Spring Harb. Protoc.
    Title
    Cold Spring Harbor protocols
    ISBN/ISSN
    1940-3402 1559-6095
    Data From Reference