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Citation
Lusk, J.B., Lam, V.Y., Tolwinski, N.S. (2017). Epidermal Growth Factor Pathway Signaling in Drosophila Embryogenesis: Tools for Understanding Cancer.  Cancers (Basel) 9(2): E16.
FlyBase ID
FBrf0234746
Publication Type
Review
Abstract

EGF signaling is a well-known oncogenic pathway in animals. It is also a key developmental pathway regulating terminal and dorsal-ventral patterning along with many other aspects of embryogenesis. In this review, we focus on the diverse roles for the EGF pathway in Drosophila embryogenesis. We review the existing body of evidence concerning EGF signaling in Drosophila embryogenesis focusing on current uncertainties in the field and areas for future study. This review provides a foundation for utilizing the Drosophila model system for research into EGF effects on cancer.

PubMed ID
PubMed Central ID
PMC5332939 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cancers (Basel)
    Title
    Cancers
    ISBN/ISSN
    2072-6694
    Data From Reference
    Gene Groups (1)
    Genes (18)