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Mohammad, F., Stewart, J.C., Ott, S., Chlebikova, K., Chua, J.Y., Koh, T.W., Ho, J., Claridge-Chang, A. (2017). Optogenetic inhibition of behavior with anion channelrhodopsins.  Nat. Methods 14(3): 271--274.
FlyBase ID
FBrf0234890
Publication Type
Research paper
Abstract

Optogenetics uses light exposure to manipulate physiology in genetically modified organisms. Abundant tools for optogenetic excitation are available, but the limitations of current optogenetic inhibitors present an obstacle to demonstrating the necessity of neuronal circuits. Here we show that anion channelrhodopsins can be used to specifically and rapidly inhibit neural systems involved in Drosophila locomotion, wing expansion, memory retrieval and gustation, thus demonstrating their broad utility in the circuit analysis of behavior.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nat. Methods
    Title
    Nature Methods
    Publication Year
    2004-
    ISBN/ISSN
    1548-7091 1548-7105
    Data From Reference