Open Close
Reference
Citation
Kohsaka, H., Guertin, P.A., Nose, A. (2017). Neural Circuits Underlying Fly Larval Locomotion.  Curr. Pharmaceut. Design 23(12): 1722--1733.
FlyBase ID
FBrf0236057
Publication Type
Review
Abstract

Locomotion is a complex motor behavior that may be expressed in different ways using a variety of strategies depending upon species and pathological or environmental conditions. Quadrupedal or bipedal walking, running, swimming, flying and gliding constitute some of the locomotor modes enabling the body, in all cases, to move from one place to another. Despite these apparent differences in modes of locomotion, both vertebrate and invertebrate species share, at least in part, comparable neural control mechanisms for locomotor rhythm and pattern generation and modulation. Significant advances have been made in recent years in studies of the genetic aspects of these control systems. Findings made specifically using Drosophila (fruit fly) models and preparations have contributed to further understanding of the key role of genes in locomotion. This review focuses on some of the main findings made in larval fruit flies while briefly summarizing the basic advantages of using this powerful animal model for studying the neural locomotor system.

PubMed ID
PubMed Central ID
PMC5470056 (PMC) (EuropePMC)
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Pharmaceut. Design
    Title
    Current Pharmaceutical Design
    Publication Year
    1995-
    ISBN/ISSN
    1381-6128
    Data From Reference