For alleles representing disease-implicated variants, positional information presented in standardized formats, using modified HGVS formats; typically for protein component only. Applies to human genes introduced into flies, analogous mutations in orthologous fly genes, and (less commonly) analogous mutations in orthologous mammalian genes. Cross references curated, if available; order of preference: ClinVar, NCBI (https://www.ncbi.nlm.nih.gov/clinvar/), UniProtKB/Swiss-Prot variant (https://web.expasy.org/variant_pages/). ClinVar provides links to UniProt variant information, so this information is not captured redundantly.