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Citation
Tettamanti, G., Casartelli, M. (2019). Cell death during complete metamorphosis.  Philos. Trans. R. Soc. Lond. B. Biol. Sci. 374(1783): 20190065.
FlyBase ID
FBrf0243331
Publication Type
Review
Abstract

In insects that undergo complete metamorphosis, cell death is essential for reshaping or removing larval tissues and organs, thus contributing to formation of the adult's body structure. In the last few decades, the study of metamorphosis in Lepidoptera and Diptera has provided broad information on the tissue remodelling processes that occur during larva-pupa-adult transition and made it possible to unravel the underlying regulatory pathways. This review summarizes recent knowledge on cell death mechanisms in Lepidoptera and other holometabolous insects, highlighting similarities and differences with Drosophila melanogaster, and discusses the role of apoptosis and autophagy in this developmental setting. This article is part of the theme issue 'The evolution of complete metamorphosis'.

PubMed ID
PubMed Central ID
PMC6711292 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Philos. Trans. R. Soc. Lond. B. Biol. Sci.
    Title
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences
    Publication Year
    1887-
    ISBN/ISSN
    0962-8436 1471-2970
    Data From Reference