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Citation
Chatterjee, D., Deng, W.M. (2019). Drosophila Model in Cancer: An Introduction.  Adv. Exp. Med. Biol. 1167(): 1--14.
FlyBase ID
FBrf0243410
Publication Type
Review
Abstract

Cancer is a cumulative manifestation of several complicated disease states that affect multiple organs. Over the last few decades, the fruit fly Drosophila melanogaster, has become a successful model for studying human cancers. The genetic simplicity and vast arsenal of genetic tools available in Drosophila provides a unique opportunity to address questions regarding cancer initiation and progression that would be extremely challenging in other model systems. In this chapter we provide a historical overview of Drosophila as a model organism for cancer research, summarize the multitude of genetic tools available, offer a brief comparison between different model organisms and cell culture platforms used in cancer studies and briefly discuss some of the latest models and concepts in recent Drosophila cancer research.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Adv. Exp. Med. Biol.
    Title
    Advances in Experimental Medicine and Biology
    Publication Year
    1976-
    ISBN/ISSN
    0065-2598
    Data From Reference