Younes, S., Al-Sulaiti, A., Nasser, E.A.A., Najjar, H., Kamareddine, L. (2020). Drosophila as a Model Organism in Host-Pathogen Interaction Studies. Front. Cell. Infect. Microbiol. 10(): 214.
FlyBase ID
FBrf0246150
Publication Type
Review
Abstract
Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host-pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in Drosophila serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans.
