Dmel\diver

General Information
Symbol	Dmel\diver	Species	D.melanogaster
Name	diver	FlyBase ID	FBte0000001
Feature type	natural transposable element
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Sequences & Components
Complete element (bp)	6112 (Kaminker et al., 2002, Frame et al., 2001)
Terminal repeat (bp)
Reference sequence	transposon_sequence_set.embl.txt.gz
Component genes
Sequence Accessions
	DDBJ/EMBL/GenBank AI541849 AJ536322 AJ536323 AW944518 AY069828 BK002325
Sequence Ontology (SO)
Transposon type	LTR_retrotransposon (Kaminker et al., 2002, Frame et al., 2001, Mugnier et al., 2008) transposable_element (Kaminker et al., 2002, Mathog, 2001.2.2, Frame et al., 2001, Mugnier et al., 2008)
Insertions & Copy Number
Copy number and comments	7 (Frame et al., 2001) 9 in euchromatin of Release 3 genome annotation, of which all are full length. (Kaminker et al., 2002)
Search for	All insertions of this transposon Insertions in the sequenced genome Insertions in other genomes
Target Site Duplication
Size (bp)
Orthologs
Curated drosophilid orthologs
Comments
	The diver element in AC004377 (P1 clone DS00837) has LTRs of 245 and 224bp matching exactly over the shorter length. It has one long open reading frame of 5224bp showing recognisable motifs corresponding to gag, protease, reverse transcriptase, RNase H and integrase. The protease and RNase H active sites are unusual (D-Q-G instead of D-S/T-G in the protease and D-G-S instead of the more usual D-A-S in RNase H). (Frame et al., 2001)
Other Information
Etymology
	element is named "Nuria" after the author's daughter "who is in constant motion". (Mathog, 2001.2.2)
External Crossreferences
Sequence Crossreferences
	DDBJ/EMBL/GenBank AI541849 AJ536322 AJ536323 AW944518 AY069828 BK002325
Other Crossreferences

Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	BcDNA:SD07683 Diver (Kapitonov and Jurka, 2003, Bowen and McDonald, 2001, Zhang and Pugh, 2011, Hamilton et al., 2009, Wang and Elgin, 2011) diver (FlyBase, 1992-, Ganko et al., 2006, Pane et al., 2011, Petrov et al., 2011, Brennecke et al., 2007, Mugnier et al., 2008, Deloger et al., 2009, Liu et al., 2011, Nefedova et al., 2011, Brennecke et al., 2008, Bergman and Bensasson, 2007, Kawamura et al., 2008, Chung et al., 2008, Malone et al., 2009, Li et al., 2009, Sienski et al., 2012) DIVER (Czech et al., 2008, Zhou et al., 2009, Olivieri et al., 2012) DIVER_I (Gunawardane et al., 2007) HDC11981 mazi (Bowen and McDonald, 2001) Nuria (Mathog, 2001.5.23, Mathog, 2001.2.2, ) tinker (Lerat et al., 2003) Tinker (Rizzon et al., 2002, Mathog, 2001.5.23, Butler, 2001.4.30, )
Name Synonym	diver (Mugnier et al., 2008, )
Secondary FlyBase IDs
	FBgn0043969 FBgn0044421 FBgn0046988 FBtp0017055
References ( 40 )

Generate a list of	All references relating to this natural transposable element ( 40 )

List References by type	Research paper ( 30 ) Supplementary material ( 1 ) Personal communication to FlyBase ( 7 ) FlyBase analysis ( 2 )
Recent research papers ( 8 )
	Olivieri et al., 2012, Mol. Cell 47(6): 954--969 The Cochaperone Shutdown Defines a Group of Biogenesis Factors Essential for All piRNA Populations in Drosophila. [FBrf0219572] Sienski et al., 2012, Cell 151(5): 964--980 Transcriptional silencing of transposons by piwi and maelstrom and its impact on chromatin state and gene expression. [FBrf0220033] Liu et al., 2011, Development 138(9): 1863--1873 PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition. [FBrf0213491] Nefedova et al., 2011, Virus Genes 42(2): 297--306 Integration specificity of LTR-retrotransposons and retroviruses in the Drosophila melanogaster genome. [FBrf0213545] Pane et al., 2011, EMBO J. 30(22): 4601--4615 The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline. [FBrf0217070] Petrov et al., 2011, Mol. Biol. Evol. 28(5): 1633--1644 Population genomics of transposable elements in Drosophila melanogaster. [FBrf0214125] Wang and Elgin, 2011, Proc. Natl. Acad. Sci. U.S.A. 108(52): 21164--21169 Drosophila Piwi functions downstream of piRNA production mediating a chromatin-based transposon silencing mechanism in female germ line. [FBrf0217081] Zhang and Pugh, 2011, PLoS ONE 6(6): e20511 Genomic Organization of H2Av Containing Nucleosomes in Drosophila Heterochromatin. [FBrf0214284] Show all research papers ...