"mini-me" elements from separate species show an overall lack of sequence identity but have a number of shared features. Perfect inverted repeats are conserved at both termini of the "mini-me" elements. At the 5' end, the inverted repeat is partially duplicated, forming a complementary palindrome. The 3' inverted repeat is located at a slightly preterminal position. A core 33bp motif that begins approximately 110bp from the 5' end of the element is also conserved, having approximately 80% sequence identity across all copies of the "mini-me" element analysed. A (TA)n-producing proto-microsatellite is present upstream of the 33bp core region and a (GTCY)n-producing proto-microsatellite is present downstream of the 33bp core region. The region between the (GTCY)n proto-microsatellite and the 3' subterminal inverted repeat is not conserved between species and can be extremely variable between copies of "mini-me" elements within a species. INE-1 elements account for approximately 1.2% of the D.melanogaster genome. INE-1 elements are 3 times more abundant on chromosome 4 as in the genome as a whole.
INE-1 elements are distributed throughout the banded region of chromosome 4, at the base of the major chromosome arms, at several telomeres and within the chromocentre.
"mini-me" elements from separate species show an overall lack of sequence identity but have a number of shared features. Perfect inverted repeats are conserved at both termini of the "mini-me" elements. At the 5' end, the inverted repeat is partially duplicated, forming a complementary palindrome. The 3' inverted repeat is located at a slightly preterminal position. A core 33bp motif that begins approximately 110bp from the 5' end of the element is also conserved, having approximately 80% sequence identity across all copies of the "mini-me" element analysed. A (TA)n-producing proto-microsatellite is present upstream of the 33bp core region and a (GTCY)n-producing proto-microsatellite is present downstream of the 33bp core region. The region between the (GTCY)n proto-microsatellite and the 3' subterminal inverted repeat is not conserved between species and can be extremely variable between copies of "mini-me" elements within a species. INE-1 elements account for approximately 1.2% of the D.melanogaster genome. INE-1 elements are 3 times more abundant on chromosome 4 as in the genome as a whole.
A repeated sequence mostly found on chromosome 4.
INE-1 has a suggested role in the heterochromatic nature of chromosome 4.
The "Dr. D" repetitive sequence (described in FBrf0048918) contains sequences of both INE-1 and 1360 transposable elements.
INE-1 elements are distributed throughout the banded region of chromosome 4, at the base of the major chromosome arms, at several telomeres and within the chromocentre.