Dmel\TART-element

General Information
Symbol	Dmel\TART-element	Species	D.melanogaster
Name	Telomere-associated retrotransposon	FlyBase ID	FBte0000335
Feature type	natural transposable element
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Sequences & Components
Complete element (bp)	10654 (Kaminker et al., 2002)
Terminal repeat (bp)
Reference sequence	transposon_sequence_set.embl.txt.gz
Component genes	TART-element\gag TART-element\pol
Sequence Accessions
	DDBJ/EMBL/GenBank AF072856 AF072857 AF188993 AF220948 AJ564669 AJ564670 AJ564671 AJ564672 AJ564673 AJ564674 AJ564678 AJ566116 AY035776 AY035777 AY561850 AY600955 L36595 U02279 U14101 U14102
Sequence Ontology (SO)
Transposon type	non_LTR_retrotransposon (Kaminker et al., 2002, Levis, 1994.8.29, Nardon et al., 2003, Shpiz et al., 2007) transposable_element (Kaminker et al., 2002, )
Insertions & Copy Number
Copy number and comments	1 in euchromatin of Release 3 genome annotation. (Kaminker et al., 2002)
Search for	All insertions of this transposon Insertions in the sequenced genome Insertions in other genomes
Target Site Duplication
Size (bp)
Orthologs
Curated drosophilid orthologs	Dame\TART-element Dvir\TART-element Dyak\TART-element (Danilevskaya et al., 1999)
Comments
	HeT-A and TART-element, previously considered to be closely related, have very different transcriptional characteristics. Additionally, features of TART-element sequence organisation resemble those of a subclass of non-LTR elements characterized by unequal terminal repeats. The distinctive transcription patterns of HeT-A and TART-element are conserved in D.yakuba. (Danilevskaya et al., 1999) Comparison of integrase/transposase domains to new elements containing the DDE signature. (Capy et al., 1997) HeT-A element and TART-element may be evolutionarily related to telomerase, in both cases an enzyme extends the end of a chromosome by adding DNA copied from an RNA template. (Pardue et al., 1997) TART-element encodes two proteins that have significant sequence homology to LINE-like retrotransposons. TART-elements preferentially transpose to broken chromosome ends as part of the essential process of maintaining telomeres. (Sheen and Levis, 1994) A transposon family of non-long terminal repeat retrotransposons found at the telomere. Evidence suggests that they can transpose to natural chromosome ends. (Levis et al., 1993) construct_comment: Associated with telomeres. (FlyBase, 1992-) TART-element may play a role in maintaining telomeres. (Sheen et al., 1992)
Other Information
Etymology

External Crossreferences
Sequence Crossreferences
	DDBJ/EMBL/GenBank AF072856 AF072857 AF188993 AF220948 AJ564669 AJ564670 AJ564671 AJ564672 AJ564673 AJ564674 AJ564678 AJ566116 AY035776 AY035777 AY561850 AY600955 L36595 U02279 U14101 U14102
Other Crossreferences

Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	anon-CH(2)6 TART (Zhang et al., 2011, Maxwell et al., 2006, Raffa et al., 2005, Pardue et al., 2001, Berezikov et al., 2000, Pardue, 2000, Konev et al., 2000, Cenci et al., 2000, Georgiev et al., 2000, Agudo et al., 1999, Dimitri and Junakovic, 1999, Labrador and Corces, 1997, Kidwell and Lisch, 1997, Biessmann and Mason, 1997, Abdulla, 1997, Boeke, 1996, Anonymous, 1994, Biessmann and Mason, 1994, Tolar et al., 1995, Savitsky et al., 2006, Biessmann et al., 2005, Louis and Vershinin, 2005, Perrod and Gasser, 2003, Biessmann and Mason, 2003, Fedic et al., 2004, Kaminker et al., 2002, Celniker et al., 2002, Yan et al., 2002, Maxwell et al., 2002, FlyBase, 1996-, Saito et al., 2006, Villasante et al., 2007, George et al., 2006, De Lucia et al., 2005, Lim and Kai, 2007, Gunawardane et al., 2007, Shpiz et al., 2011, Shpiz et al., 2007, Brennecke et al., 2007, Savitsky et al., 2002, Kalmykova et al., 2008, Yin and Lin, 2007, Nardon et al., 2003, Maxwell et al., 2008, Brennecke et al., 2008, Anand and Kai, 2012, Malone et al., 2009, Cenci et al., 2003, Mason et al., 2003, Navarro et al., 2009, Slawson et al., 2006, Patil and Kai, 2010, Zhou et al., 2009, Moshkovich and Lei, 2010, Rozhkov et al., 2010, Rashkova et al., 2003, Pek et al., 2012, Preall et al., 2012) Tart (Rizzon et al., 2002, Pane et al., 2007, Pane et al., 2007, Chen et al., 2007, Chen et al., 2007) TART_B1 (Olivieri et al., 2012) TART^mel (Casacuberta et al., 2007) TART-B1 (Levis, 1994.8.29, Blesa and Martinez-Sebastian, 1997, FlyBase, 1996-, Maxwell et al., 2008) Tart-B1 (Bartolome et al., 2002) TART-B2 transposon putative reverse (Levis, 1994.8.29) TART-element (Debaryshe and Pardue, 2011, Shpiz et al., 2009) TART element (Gonzalez and Bornens, 2000) TART-repeat (FlyBase, 1996-) Telomere Associated Sequence (FlyBase, 1996-)
Name Synonym	TART (Shpiz et al., 2009) Telomere-associated retrotransposon
Secondary FlyBase IDs
	FBgn0004904 FBgn0013398 FBtp0011466
References ( 139 )

Generate a list of	All references relating to this natural transposable element ( 139 )

List References by type	Research paper ( 79 ) Supplementary material ( 2 ) Review ( 27 ) Abstract ( 20 ) FlyBase analysis ( 2 ) DNA/RNA sequence record ( 3 ) Conference report ( 5 ) Book review ( 1 )
Recent research papers ( 7 )
	Anand and Kai, 2012, EMBO J. 31(4): 870--882 The tudor domain protein Kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila. [FBrf0217541] Olivieri et al., 2012, Mol. Cell 47(6): 954--969 The Cochaperone Shutdown Defines a Group of Biogenesis Factors Essential for All piRNA Populations in Drosophila. [FBrf0219572] Pek et al., 2012, Development 139(24): 4505--4513 Polo-mediated phosphorylation of Maelstrom regulates oocyte determination during oogenesis in Drosophila. [FBrf0220058] Preall et al., 2012, RNA 18(8): 1446--1457 shutdown is a component of the Drosophila piRNA biogenesis machinery. [FBrf0218942] Debaryshe and Pardue, 2011, Genetics 187(1): 51--60 Differential maintenance of DNA sequences in telomeric and centromeric heterochromatin. [FBrf0212756] Shpiz et al., 2011, Nucleic Acids Res. 39(20): 8703--8711 Mechanism of the piRNA-mediated silencing of Drosophila telomeric retrotransposons. [FBrf0216525] Zhang et al., 2011, Mol. Cell 44(4): 572--584 Heterotypic piRNA Ping-Pong Requires Qin, a Protein with Both E3 Ligase and Tudor Domains. [FBrf0216809] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...