Dmer\R2-element

General Information
Symbol	Dmer\R2-element	Species	D.mercatorum mercatorum
Name	R2-element	FlyBase ID	FBte0000759
Feature type	natural transposable element
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Sequences & Components
Complete element (bp)
Terminal repeat (bp)
Reference sequence	transposon_sequence_set.embl.txt.gz
Component genes	Dmer\R2-element\ORF
Sequence Accessions
	DDBJ/EMBL/GenBank AF015685
Sequence Ontology (SO)
Transposon type	transposable_element
Insertions & Copy Number
Copy number and comments
Search for	All insertions of this transposon Insertions in the sequenced genome Insertions in other genomes
Target Site Duplication
Size (bp)
Orthologs
Curated drosophilid orthologs	Dmel\R2-element
Comments
	Flies of the 'abnormal abdomen' strain have a higher level of Dmer\bb units with Dmer\R1-element and Dmer\R2-element insertions than wild-type flies. Uninserted Dmer\bb units do not undergo general underreplication in contrast to wild-type, although differential underreplication of the inserted Dmer\bb units does occur in the 'abnormal abdomen' strain. (Malik and Eickbush, 1999) Elements R1 and R2 are subject to the same recombinational forces that give rise to the concerted evolution of the rDNA units. Molecular phylogenetic analysis of elements from 16 Drosophila species suggests these elements have been stable components of the rDNA locus for the 50-70 million year history of the Drosophila genus. (Eickbush et al., 1997)
Other Information
Etymology

External Crossreferences
Sequence Crossreferences
	DDBJ/EMBL/GenBank AF015685
Other Crossreferences

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Dmer\R2-element R2 Dmer (Ruschak et al., 2004)
Name Synonym	R2-element R2 element (Ruschak et al., 2004)
Secondary FlyBase IDs
	FBgn0023313
References ( 9 )
Research paper	Ruschak et al., 2004, RNA 10(6): 978--987 Secondary structure models of the 3' untranslated regions of diverse R2 RNAs. [FBrf0175117] Gentile et al., 2001, Mol. Biol. Evol. 18(2): 235--245 Multiple lineages of R1 retrotransposable elements can coexist in the rDNA loci of Drosophila. [FBrf0132406] Biemont and Cizeron, 1999, Genetica 105(1): 43--62 Distribution of transposable elements in Drosophila species. [FBrf0111330] Burke et al., 1999, Mol. Biol. Evol. 16(4): 502--511 The domain structure and retrotransposition mechanism of R2 elements are conserved throughout arthropods. [FBrf0108488] Malik and Eickbush, 1999, Genetics 151(2): 653--665 Retrotransposable elements R1 and R2 in the rDNA units of Drosophila mercatorum. Abnormal abdomen revisited. [FBrf0106904] Malik et al., 1999, Mol. Biol. Evol. 16(6): 793--805 The age and evolution of non-LTR retrotransposable elements. [FBrf0108898] Eickbush et al., 1997, Genetica 100(1-3): 49--61 Evolution of R1 and R2 in the rDNA units of the genus Drosophila. [FBrf0099794] Lathe and Eickbush, 1997, Mol. Biol. Evol. 14(12): 1232--1241 A single lineage of R2 retrotransposable elements is an active, evolutionarily stable component of the Drosophila rDNA locus. [FBrf0099899]
Letter	Burke et al., 1998, Nature 392(6672): 141--142 Are retrotransposons long-term hitchhikers? [FBrf0102107]