Tni\piggyBac

General Information
Symbol	Tni\piggyBac	Species	T.ni
Name		FlyBase ID	FBte0000964
Feature type	natural transposable element
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Sequences & Components
Complete element (bp)
Terminal repeat (bp)
Reference sequence	transposon_sequence_set.embl.txt.gz
Component genes	Tni\piggyBac\T
Sequence Accessions
	DDBJ/EMBL/GenBank AY196826
Sequence Ontology (SO)
Transposon type	engineered_foreign_region transposable_element
Insertions & Copy Number
Copy number and comments
Search for	All insertions of this transposon Insertions in the sequenced genome Insertions in other genomes
Target Site Duplication
Size (bp)	4 (Handler and Harrell, 1999)
Orthologs
Curated drosophilid orthologs
Comments
	The density of insertions of Tni\piggyBac transgenic constructs in D. melanogaster is significantly lower in underreplicated regions of the genome (URs) compared to neighboring regions or the genomic average. Testis-specific genes have a low frequency of insertions of Tni\piggyBac transgenic constructs. (Babenko et al., 2010) A TTAA duplicated target site is characteristic of Tni\piggyBac integrations. (Handler and Harrell, 1999)
Other Information
Etymology

External Crossreferences
Sequence Crossreferences
	DDBJ/EMBL/GenBank AY196826
Other Crossreferences

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	piggyBac (Hacker et al., 2003, Li et al., 2001, Li et al., 2005, Bossin et al., 2007, Spradling et al., 2011, Babenko et al., 2010) PiggyBac (Witsell et al., 2009) Tni\piggyBac
Name Synonym
Secondary FlyBase IDs
	FBgn0024278
References ( 144 )

Generate a list of	All references relating to this natural transposable element ( 144 )

List References by type	Research paper ( 104 ) Supplementary material ( 12 ) Review ( 4 ) Personal communication to FlyBase ( 12 ) Abstract ( 10 ) FlyBase analysis ( 2 )
Recent research papers ( 62 )
	Chen et al., 2013, Neuropharmacology 67: 25--31 Mutations in Bacchus reveal a tyramine-dependent nuclear regulator for acute ethanol sensitivity in Drosophila. [FBrf0220671] Meiklejohn et al., 2013, PLoS Genet. 9(1): e1003238 An Incompatibility between a Mitochondrial tRNA and Its Nuclear-Encoded tRNA Synthetase Compromises Development and Fitness in Drosophila. [FBrf0220717] Wang et al., 2013, Nat. Struct. Mol. Biol. 20(2): 202--209 Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. [FBrf0220693] Akerboom et al., 2012, J. Neurosci. 32(40): 13819--13840 Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging. [FBrf0219564] Akiyama et al., 2012, Sci. Signal. 5(218): ra28 A Large Bioactive BMP Ligand with Distinct Signaling Properties Is Produced by Alternative Proconvertase Processing. [FBrf0217914] Bayat et al., 2012, PLoS Biol. 10(3): e1001288 Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans. [FBrf0217845] Domingues and Ryoo, 2012, Cell Death Differ. 19(3): 470--477 Drosophila BRUCE inhibits apoptosis through non-lysine ubiquitination of the IAP-antagonist REAPER. [FBrf0217448] Dornier et al., 2012, J. Cell Biol. 199(3): 481--496 TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals. [FBrf0219816] Dourlen et al., 2012, PLoS Genet. 8(7): e1002833 Drosophila Fatty Acid transport protein regulates rhodopsin-1 metabolism and is required for photoreceptor neuron survival. [FBrf0219056] Fan et al., 2012, Dev. Biol. 366(2): 172--184 Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner. [FBrf0218374] Florentin and Arama, 2012, J. Cell Biol. 196(4): 513--527 Caspase levels and execution efficiencies determine the apoptotic potential of the cell. [FBrf0217486] Fransson et al., 2012, Oncogene 31(27): 3277--3286 p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in tumors. [FBrf0219466] Fuchs et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(5): 1572--1577 Transcriptional interpretation of the EGF receptor signaling gradient. [FBrf0217355] Giagtzoglou et al., 2012, J. Cell Biol. 196(1): 65--83 dEHBP1 Controls Exocytosis and Recycling of Delta During Asymmetric Divisions. [FBrf0217836] Jeong et al., 2012, Neuron 76(4): 721--734 The Control of Semaphorin-1a-Mediated Reverse Signaling by Opposing Pebble and RhoGAPp190 Functions in Drosophila. [FBrf0219982] Jin et al., 2012, PLoS ONE 7(7): e40912 Similarities of Drosophila rab GTPases Based on Expression Profiling: Completion and Analysis of the rab-Gal4 Kit. [FBrf0219021] Lloyd et al., 2012, Neuron 74(2): 344--360 The p150(Glued) CAP-Gly Domain Regulates Initiation of Retrograde Transport at Synaptic Termini. [FBrf0218160] Loh et al., 2012, J. Cell Sci. 125(19): 4457--4462 The conserved kinase SRPK regulates karyosome formation and spindle microtubule assembly in Drosophila oocytes. [FBrf0220249] Miller et al., 2012, J. Neurogenet. 26(3-4): 317--327 A mutation in Drosophila Aldolase Causes Temperature-Sensitive Paralysis, Shortened Lifespan, and Neurodegeneration. [FBrf0220234] Muerdter et al., 2012, RNA 18(1): 42--52 Production of artificial piRNAs in flies and mice. [FBrf0217373] Osanai-Futahashi et al., 2012, Nat. Commun. 3: 1295 A visible dominant marker for insect transgenesis. [FBrf0220343] Pöyhönen et al., 2012, G3 (Bethesda) 2(3): 331--338 Homology-dependent silencing by an exogenous sequence in the Drosophila germline. [FBrf0217712] Rahman et al., 2012, Nat. Neurosci. 15(6): 871--875 Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections. [FBrf0219393] Rahman et al., 2012, Traffic 13(12): 1680--1692 Drosophila mauve Mutants Reveal a Role of LYST Homologs Late in the Maturation of Phagosomes and Autophagosomes. [FBrf0220730] Rincon-Arano et al., 2012, Cell 151(6): 1214--1228 UpSET Recruits HDAC Complexes and Restricts Chromatin Accessibility and Acetylation at Promoter Regions. [FBrf0220189] Roberts et al., 2012, PLoS ONE 7(2): e31284 Defining Components of the ßcatenin Destruction Complex and Exploring Its Regulation and Mechanisms of Action during Development. [FBrf0217546] Roberts et al., 2012, Mol. Biol. Cell 23(11): 2041--2056 Regulation of Wnt signaling by the tumor suppressor adenomatous polyposis coli does not require the ability to enter the nucleus or a particular cytoplasmic localization. [FBrf0218500] Sluder et al., 2012, PLoS ONE 7(5): e34712 Spiroindolines identify the vesicular acetylcholine transporter as a novel target for insecticide action. [FBrf0219686] Szabad et al., 2012, G3 (Bethesda) 2(9): 1095--1102 An assay to detect in vivo Y chromosome loss in Drosophila wing disc cells. [FBrf0219495] Tsubouchi et al., 2012, Curr. Biol. 22(22): 2124--2134 Dendritic Filopodia, Ripped Pocket, NOMPC, and NMDARs Contribute to the Sense of Touch in Drosophila Larvae. [FBrf0219946] Turki-Judeh and Courey, 2012, PLoS ONE 7(2): e30610 The unconserved groucho central region is essential for viability and modulates target gene specificity. [FBrf0217447] Vilain et al., 2012, PLoS Genet. 8(1): e1002456 The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants. [FBrf0217195] Vos et al., 2012, Science 336(6086): 1306--1310 Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency. [FBrf0218543] Xia et al., 2012, PLoS Biol. 10(1): e1001238 USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization. [FBrf0218247] Xie et al., 2012, Dev. Biol. 363(2): 399--412 Drosophila Epsin's role in Notch ligand cells requires three Epsin protein functions: The lipid binding function of the ENTH domain, a single Ubiquitin interaction motif, and a subset of the C-terminal protein binding modules. [FBrf0217494] Yang et al., 2012, Dev. Cell 22(5): 1041--1051 Phf7 controls male sex determination in the Drosophila germline. [FBrf0218344] Zhou and Hong, 2012, Development 139(16): 2891--2896 Drosophila Patj plays a supporting role in apical-basal polarity but is essential for viability. [FBrf0219035] Anderson et al., 2011, Development 138(10): 1957--1966 The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila development. [FBrf0213580] Chan et al., 2011, Curr. Biol. 21(20): 1704--1715 Systematic discovery of rab GTPases with synaptic functions in Drosophila. [FBrf0216517] Datta et al., 2011, Dev. Biol. 360(2): 391--402 A dissection of the teashirt and tiptop genes reveals a novel mechanism for regulating transcription factor activity. [FBrf0216557] Dunipace et al., 2011, Development 138(18): 4075--4084 Complex interactions between cis-regulatory modules in native conformation are critical for Drosophila snail expression. [FBrf0214809] Gasnereau et al., 2011, J. Biol. Chem. 286(50): 43324--43333 Identification of an endocytosis motif in an intracellular loop of wntless protein, essential for its recycling and the control of wnt protein signaling. [FBrf0216938] Gohl et al., 2011, Nat. Methods 8(3): 231--237 A versatile in vivo system for directed dissection of gene expression patterns. [FBrf0213287] Han et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(23): 9673--9678 Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila. [FBrf0213916] Hara et al., 2011, J. Neurosci. 31(27): 9982--9990 Post-Translational Regulation and Nuclear Entry of TIMELESS and PERIOD Are Affected in New timeless Mutant. [FBrf0214253] Kabil et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(40): 16831--16836 Increased transsulfuration mediates longevity and dietary restriction in Drosophila. [FBrf0216270] Leonardi et al., 2011, Development 138(16): 3569--3578 Multiple O-glucosylation sites on Notch function as a buffer against temperature-dependent loss of signaling. [FBrf0214548] Liu et al., 2011, Science 334(6062): 1565--1569 RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release. [FBrf0216992] Miśkiewicz et al., 2011, Neuron 72(5): 776--788 ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family Member Bruchpilot. [FBrf0216903] Pandey et al., 2011, PLoS ONE 6(11): e28106 The Glucuronyltransferase GlcAT-P Is Required for Stretch Growth of Peripheral Nerves in Drosophila. [FBrf0216828] Petersen and Stowers, 2011, PLoS ONE 6(9): e24531 A Gateway MultiSite Recombination Cloning Toolkit. [FBrf0215584] Rees et al., 2011, Mol. Cell. Proteomics 10(6): M110.002386 In Vivo Analysis of Proteomes and Interactomes Using Parallel Affinity Capture (iPAC) Coupled to Mass Spectrometry. [FBrf0213845] Roberts et al., 2011, Mol. Biol. Cell 22(11): 1845--1863 Deconstructing the sscatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. [FBrf0213765] Sinenko et al., 2011, EMBO Rep. 13(1): 83--89 Oxidative stress in the haematopoietic niche regulates the cellular immune response in Drosophila. [FBrf0217071] Spradling et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(38): 15948--15953 Drosophila P elements preferentially transpose to replication origins. [FBrf0215815] Stowers, 2011, Fly 5(4): 371--378 An efficient method for recombineering GAL4 and QF drivers. [FBrf0216432] Tong et al., 2011, Neuron 71(3): 447--459 Rich Regulates Target Specificity of Photoreceptor Cells and N-Cadherin Trafficking in the Drosophila Visual System via Rab6. [FBrf0214681] Uytterhoeven et al., 2011, Cell 145(1): 117--132 Loss of skywalker reveals synaptic endosomes as sorting stations for synaptic vesicle proteins. [FBrf0213384] Venken et al., 2011, Nat. Methods 8(9): 737--743 MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. [FBrf0216331] White et al., 2011, J. Cell Biol. 193(4): 677--694 Drosophila histone locus bodies form by hierarchical recruitment of components. [FBrf0213662] Wu et al., 2011, Neuron 70(2): 281--298 A combinatorial semaphorin code instructs the initial steps of sensory circuit assembly in the Drosophila CNS. [FBrf0213571] Zhang et al., 2011, Mol. Cell 44(4): 572--584 Heterotypic piRNA Ping-Pong Requires Qin, a Protein with Both E3 Ligase and Tudor Domains. [FBrf0216809] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...