Dmel\P{UAS-lacZ.B}melt^Bg4-1-2 Insertion

General Information
Symbol	Dmel\P{UAS-lacZ.B}melt^Bg4-1-2	Species	D. melanogaster
Name		FlyBase ID	FBti0002128
Feature type	transposable_element_insertion_site
Description
Inserted element	P{UAS-lacZ.B}	Expression data
Affected gene(s)	melt	Viability / fertility	viable
Causes allele(s)	melt^Bg4-1-2	Stock availability	4 publicly available
LINE ID
Genomic Location
Chromosomal location	3L ( 65E4-65E5 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)	2 (Apitz et al., 2004, Brand and Perrimon, 1994)
Sequence Location
Orientation	? (Tracey et al., 2000)
Cytological location (computed by FlyBase)	65E4-65E5 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{UAS-lacZ.B}
Location-dependent role
Size	9.756Kb
Associated alleles	Ecol\lacZ^Scer\UAS.cBa w^+mC
Molecular map
Affected Gene(s)
Insertion may affect gene	melt (Mikeladze-Dvali et al., 2005)
Alleles and Phenotypes
Causes alleles	melt^Bg4-1-2 (Mikeladze-Dvali et al., 2005)

Lethality References viable (Brand and Perrimon, 1994)
Sterility References
Phenotype Manifest In
	photoreceptor cell R8 of pale ommatidium \| supernumerary (Mikeladze-Dvali et al., 2005) photoreceptor cell R8 of yellow ommatidium (Mikeladze-Dvali et al., 2005)
Detailed Description
Statement Reference In melt^Bg4-1-2 eyes, about 90% of R8 photoreceptor cells adopt a p fate, while only 30% adopt this fate in wild-type eyes. (Mikeladze-Dvali et al., 2005)
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 4 )
Bloomington	1776 w¹¹¹⁸; P{UAS-lacZ.B}melt^Bg4-1-2 4409 y¹ w^*; P{AyGAL4}25 P{UAS-lacZ.B}melt^Bg4-1-2/CyO, y⁺
Kyoto	106500 w^; P{UAS-lacZ.B}melt^Bg4-1-2 107722 y¹ w^; P{AyGAL4}25 P{UAS-lacZ.B}melt^Bg4-1-2/CyO, y⁺
Linkouts
Comments
	Generated by A. Brand. (Brand, 1997.6.30) May be the same as P{UAS-lacZ.B}4-12. (Brand and Perrimon, 1994)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	bg4-1-2 (Frasch, 1995) Bg41-2 (Yeh et al., 1995, Gustafson and Boulianne, 1996) P{UAS-lacZ.B}4-1-2 (Tracey et al., 2000, FlyBase, 1992-) P{UAS-lacZ.B}Bg4-1-2 (Hewes et al., 2003, FlyBase, 1992-) P{UAS-lacZ.B}melt^Bg4-1-2 (FlyBase, 1992-) P{UAS-lacZ}Bg4-1-2 (Brand, 1997.6.30) P{w[+mC]=UAS-lacZ.B}Bg4-2-4b (Mikeladze-Dvali et al., 2005) P{w^+mC=UAS-lacZ.B}4-1-2 (FlyBase, 1992-) UASlacZ4-1-2 (Holz et al., 2003) UAS-lacZ.B^Bg4-1-2 (Apitz et al., 2004) UAS-lacZ^4-1-2 (Klapper et al., 2001) UAS-lacZ^4-1-2Bg 4-1-2βg 4-1-2 (Brand and Perrimon, 1994) UAS-lacZ^4-2-1 (Klapper et al., 2002) UAS-lacZ^Bg4-1-2 ULZ 4.1.2 (Renn et al., 1999)
Secondary FlyBase IDs
	FBti0001021
References ( 15 )
Research paper	Broughton et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102(8): 3105--3110 Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. [FBrf0184236] Mikeladze-Dvali et al., 2005, Cell 122(5): 775--787 The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors. [FBrf0187233] Apitz et al., 2004, Dev. Genes Evol. 214(9): 453--459 Identification of regulatory modules mediating specific expression of the roughest gene in Drosophila melanogaster. [FBrf0180136] Hewes et al., 2003, Development 130(9): 1771--1781 The bHLH protein dimmed controls neuroendocrine cell differentiation in Drosophila. [FBrf0158877] Holz et al., 2003, Development 130(20): 4955--4962 The two origins of hemocytes in Drosophila. [FBrf0162082] Klapper et al., 2002, Mech. Dev. 110(1-2): 85--96 The formation of syncytia within the visceral musculature of the Drosophila midgut is dependent on duf, sns and mbc. [FBrf0141646] Klapper et al., 2001, Development 128(13): 2517--2524 A new approach reveals syncytia within the visceral musculature of Drosophila melanogaster. [FBrf0137447] Tracey et al., 2000, Genetics 154(1): 273--284 Quantitative analysis of gene function in the Drosophila embryo. [FBrf0123220] Renn et al., 1999, J. Neurobiol. 41(2): 189--207 Genetic analysis of the Drosophila ellipsoid body neuropil: Organization and development of the central complex. [FBrf0111476] Gustafson and Boulianne, 1996, Genome 39(1): 174--182 Distinct expression patterns detected within individual tissues by the GAL4 enhancer trap technique. [FBrf0086431] Frasch, 1995, Nature 374(6521): 464--467 Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo. [FBrf0080027] Yeh et al., 1995, Proc. Natl. Acad. Sci. U.S.A. 92(15): 7036--7040 Green fluorescent protein as a vital marker and reporter of gene expression in Drosophila. [FBrf0082810] Brand and Perrimon, 1994, Genes Dev. 8(5): 629--639 Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. [FBrf0076497]
Personal communication to FlyBase	Brand, 1997.6.30, P{GawB} insertions. P{GawB} insertions. [FBrf0098595]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{UAS-lacZ.B}meltBg4-1-2 Insertion

Dmel\P{UAS-lacZ.B}melt^Bg4-1-2 Insertion