Dmel\P{UAS-lacZ.B}melt^Bg4-1-2 Insertion

General Information
Symbol	Dmel\P{UAS-lacZ.B}melt^Bg4-1-2	Species	D. melanogaster
Name		FlyBase ID	FBti0002128
Feature type	transposable_element_insertion_site	Created / Updated	1997-03-21/2007-06-14
Description
Inserted element	P{UAS-lacZ.B}	Localized function
Affected gene(s)	melt	Expression data
Causes allele(s)	melt^Bg4-1-2	Viability / fertility	viable
LINE ID		Stock availability
Genomic Location
Chromosomal location	3L ( 65E4-65E5 )	Sequence location
Detailed Mapping Data
Chromosome (arm)	2 (Apitz et al., 2004, Brand and Perrimon, 1994)
Sequence Location
Orientation	? (Tracey et al., 2000)
Cytological location (computed by FlyBase)	65E4-65E5 ( near gene of known cytology )
Cytological location (reported)
Chromosome in situ
Sequence Data
Flanking sequence
Inserted Element
Construct	P{UAS-lacZ.B}
Location-dependent role
Size	9.756Kb
Associated alleles	w^+mC Ecol\lacZ^Scer\UAS.cBa
Molecular map
Transposon class
Element type
Affected Gene(s)
Insertion within gene
Insertion may affect gene	melt (Mikeladze-Dvali et al., 2005)
Orientation (relative to gene)	Gene Orientation References
Alleles and Phenotypes
Causes alleles	melt^Bg4-1-2 (Mikeladze-Dvali et al., 2005)

Lethality References viable (Brand and Perrimon, 1994)
Sterility References
Phenotype Manifest In
	photoreceptor cell R8 of pale ommatidium \| supernumerary (Mikeladze-Dvali et al., 2005) photoreceptor cell R8 of yellow ommatidium (Mikeladze-Dvali et al., 2005)
Detailed Description
Statement Reference In melt[Bg4-1-2] eyes, about 90% of R8 photoreceptor cells adopt a p fate, while only 30% adopt this fate in wild-type eyes. (Mikeladze-Dvali et al., 2005)
Expression Data
Reporter Expression
Stage Tissue/Position Reference
Additional Information
Statement Reference

Assay mode
Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 4 )
Kyoto	106500 w^; P{UAS-lacZ.B}melt^Bg4-1-2 107722 y¹ w^; P{AyGAL4}25 P{UAS-lacZ.B}melt^Bg4-1-2/CyO, y⁺
Bloomington	1776 w¹¹¹⁸; P{UAS-lacZ.B}melt^Bg4-1-2 4409 y¹ w^*; P{AyGAL4}25 P{UAS-lacZ.B}melt^Bg4-1-2/CyO, y⁺
Linkouts
Comments
	May be the same as P{UAS-lacZ.B}4-12. (Brand and Perrimon, 1994) Generated by A. Brand. (Brand, 1997.6.30)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	bg4-1-2 (Frasch, 1995) Bg41-2 (Yeh et al., 1995, Gustafson and Boulianne, 1996) P{UAS-lacZ.B}4-1-2 (Tracey et al., 2000, FlyBase, 1992-) P{UAS-lacZ.B}Bg4-1-2 (Hewes et al., 2003, FlyBase, 1992-) P{UAS-lacZ.B}melt^Bg4-1-2 (FlyBase, 1992-) P{UAS-lacZ}Bg4-1-2 (Brand, 1997.6.30) P{w[+mC]=UAS-lacZ.B}Bg4-2-4b (Mikeladze-Dvali et al., 2005) P{w^+mC=UAS-lacZ.B}4-1-2 (FlyBase, 1992-) UASlacZ4-1-2 (Holz et al., 2003) UAS-lacZ.B^Bg4-1-2 (Apitz et al., 2004) UAS-lacZ^4-1-2 (Klapper et al., 2001) UAS-lacZ^4-1-2Bg 4-1-2βg 4-1-2 (Brand and Perrimon, 1994) UAS-lacZ^4-2-1 (Klapper et al., 2002) UAS-lacZ^Bg4-1-2 ULZ 4.1.2 (Renn et al., 1999)
Secondary FlyBase IDs
	FBti0001021
References ( 15 )
Research paper	Broughton et al., 2005, Proc. Natl. Acad. Sci. USA 102(8): 3105--3110 Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. [FBrf0184236] Mikeladze-Dvali et al., 2005, Cell 122(5): 775--787 The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors. [FBrf0187233] Apitz et al., 2004, Dev. Genes Evol. 214(9): 453--459 Identification of regulatory modules mediating specific expression of the roughest gene in Drosophila melanogaster. [FBrf0180136] Hewes et al., 2003, Development 130(9): 1771--1781 The bHLH protein dimmed controls neuroendocrine cell differentiation in Drosophila. [FBrf0158877] Holz et al., 2003, Development 130(20): 4955--4962 The two origins of hemocytes in Drosophila. [FBrf0162082] Klapper et al., 2002, Mech. Dev. 110(1-2): 85--96 The formation of syncytia within the visceral musculature of the Drosophila midgut is dependent on duf, sns and mbc. [FBrf0141646] Klapper et al., 2001, Development 128(13): 2517--2524 A new approach reveals syncytia within the visceral musculature of Drosophila melanogaster. [FBrf0137447] Tracey et al., 2000, Genetics 154(1): 273--284 Quantitative analysis of gene function in the Drosophila embryo. [FBrf0123220] Renn et al., 1999, J. Neurobiol. 41(2): 189--207 Genetic analysis of the Drosophila ellipsoid body neuropil: Organization and development of the central complex. [FBrf0111476] Gustafson and Boulianne, 1996, Genome 39(1): 174--182 Distinct expression patterns detected within individual tissues by the GAL4 enhancer trap technique. [FBrf0086431] Frasch, 1995, Nature 374(6521): 464--467 Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo. [FBrf0080027] Yeh et al., 1995, Proc. Natl. Acad. Sci. USA 92(15): 7036--7040 Green fluorescent protein as a vital marker and reporter of gene expression in Drosophila. [FBrf0082810] Brand and Perrimon, 1994, Genes Dev. 8(5): 629--639 Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. [FBrf0076497]
Personal communication to FlyBase	Brand, 1997.6.30, P{GawB} insertions. P{GawB} insertions. [FBrf0098595]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]

Dmel\P{UAS-lacZ.B}meltBg4-1-2 Insertion

Dmel\P{UAS-lacZ.B}melt^Bg4-1-2 Insertion