Dmel\P{GAL4}zfh2^MS209 Insertion

General Information
Symbol	Dmel\P{GAL4}zfh2^MS209	Species	D. melanogaster
Name		FlyBase ID	FBti0002375
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GAL4}	Expression data	GAL4 reporter/driver
Affected gene(s)	Scer\GAL4, zfh2	Viability / fertility
Causes allele(s)	Scer\GAL4^zfh2-MS209, zfh2^MS209	Stock availability	1 publicly available
LINE ID
Genomic Location
Chromosomal location	4 ( 102C3-102C4 )	Sequence location
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	102C3-102C4 ( near gene of known cytology )
Cytological location (reported)	102C1 (reported as inferred from sequence location) (Kramps et al., 2002)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GAL4}
Location-dependent role	GAL4 driver/enhancer trap (FlyBase, 1992-)
Size
Associated alleles	Scer\GAL4^unspecified
Molecular map
Affected Gene(s)
Insertion may affect gene	Scer\GAL4 (Dichtel-Danjoy et al., 2009, Capdevila and Guerrero, 1994, Whitworth and Russell, 2003, Brentrup et al., 2000, Baena-Lopez et al., 2003, Russell, 2000, de Celis et al., 1999, Milan et al., 1997) zfh2 (Whitworth and Russell, 2003, Terriente et al., 2008)
Alleles and Phenotypes
Causes alleles	Scer\GAL4^zfh2-MS209 (Capdevila and Guerrero, 1994, Whitworth and Russell, 2003, Dichtel-Danjoy et al., 2009, Brentrup et al., 2000, Baena-Lopez et al., 2003, Russell, 2000, de Celis et al., 1999, Milan et al., 1997) zfh2^MS209 (Whitworth and Russell, 2003, Terriente et al., 2008)

Lethality References viable \| poor (Whitworth and Russell, 2003)
Sterility References
Phenotype Manifest In
	alula (Whitworth and Russell, 2003) medial costal vein (Whitworth and Russell, 2003) wing \| proximal (Whitworth and Russell, 2003) wing disc (Whitworth and Russell, 2003) wing vein L1 (Whitworth and Russell, 2003)
Detailed Description
Statement Reference zfh2^MS209 homozygotes display a recessive proximal wing phenotype which consists of deletion of both anterior and posterior wing structures, including the medial costa, parts of the radius, and the alula. (Whitworth and Russell, 2003)
Expression Data
Reporter Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference third instar larval stage wing disc \| proximal (Capdevila and Guerrero, 1994) wing disc \| restricted (Capdevila and Guerrero, 1994)
Additional Information
Statement Reference

Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	25676 w^*; P{GAL4}zfh2^MS209/In(4)ci^D, ci^D pan^ciD
Linkouts
Comments
	Maps to clone: BACH57F14Maps to clone: BACN21F17Maps to clone: BACN23A06Maps to clone: BACN24M16 (Locke et al., 2000) May be P{GawB}MS209. (Capdevila and Guerrero, 1994)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	Gal4-MS209 (de Celis et al., 1999) MS209 (Brentrup et al., 2000, Russell, 2000, Locke et al., 2000) MS 209 (Kramps et al., 2002) MS209-GAL4 (Dichtel-Danjoy et al., 2009) P{GAL4}MS209 (Kramps et al., 2002, FlyBase, 1992-) P{GAL4}zfh2^MS209 (FlyBase, 1992-) zfh2^MS209 (Terriente et al., 2008) zfh-2^MS209 GAL4 (Baena-Lopez et al., 2003) zfh2^MS209-GAL4 (Dichtel-Danjoy et al., 2009)
Secondary FlyBase IDs

References ( 12 )
Research paper	Dichtel-Danjoy et al., 2009, Development 136(5): 761--769 SoxF is part of a novel negative-feedback loop in the wingless pathway that controls proliferation in the Drosophila wing disc. [FBrf0206770] Terriente et al., 2008, Dev. Biol. 320(1): 102--112 The Drosophila gene zfh2 is required to establish proximal-distal domains in the wing disc. [FBrf0207390] Baena-Lopez et al., 2003, Development 130(26): 6497--6506 Wg and Egfr signalling antagonise the development of the peripodial epithelium in Drosophila wing discs. [FBrf0167522] Whitworth and Russell, 2003, Dev. Biol. 254(2): 277--288 Temporally dynamic response to Wingless directs the sequential elaboration of the proximodistal axis of the Drosophila wing. [FBrf0157154] Kramps et al., 2002, Cell 109(1): 47--60 Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. [FBrf0146918] Brentrup et al., 2000, Development 127(21): 4729--4741 Regulation of Drosophila wing vein patterning: net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling. [FBrf0129742] Locke et al., 2000, Genetics 155(3): 1175--1183 A physical map of the polytenized region (101EF-102F) of chromosome 4 in Drosophila melanogaster. [FBrf0128554] Russell, 2000, Molec. gen. Genet. 263(4): 690--701 The Drosophila dominant wing mutation Dichaete results from ectopic expression of a Sox-domain gene. [FBrf0128629] de Celis et al., 1999, Development 126(12): 2653--2662 Regulation of the spalt/spalt-related gene complex and its function during sensory organ development in the Drosophila thorax. [FBrf0108695] Milan et al., 1997, Proc. Natl. Acad. Sci. USA 94(11): 5691--5696 Developmental parameters of cell death in the wing disc of Drosophila. [FBrf0093608] Capdevila and Guerrero, 1994, EMBO J. 13(19): 4459--4468 Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings. [FBrf0076434]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]

Dmel\P{GAL4}zfh2MS209 Insertion

Dmel\P{GAL4}zfh2^MS209 Insertion