Dmel\P{lacW}E7-2-36 Insertion

General Information
Symbol	Dmel\P{lacW}E7-2-36	Species	D. melanogaster
Name		FlyBase ID	FBti0002469
Feature type	transposable_element_insertion_site
Description
Inserted element	P{lacW}	Expression data	lacZ reporter
Affected gene(s)	Ecol\lacZ, RluA-1	Viability / fertility
Causes allele(s)	Ecol\lacZ^E7-2-36, RluA-1^E7-2-36	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	2L ( 31E6-31F1 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)	2 (Uemura et al., 1989)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	31E6-31F1 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{lacW}
Location-dependent role	lacZ enhancer trap (Bier et al., 1989)
Size	10.691Kb
Associated alleles	Ecol\lacZ^P\T.W w^+mC
Molecular map
Affected Gene(s)
Insertion may affect gene	Ecol\lacZ (Uemura et al., 1989, Brenman et al., 2001, Grueber et al., 2003, Ledent et al., 1998, Kim et al., 2006, Moore et al., 2002, Orgogozo et al., 2001, Usui-Ishihara et al., 2000, Huang et al., 2000, Brewster et al., 2001, Dye et al., 1998, Brewster and Bodmer, 1995, Vervoort et al., 1995, Vervoort et al., 1997, Gautier et al., 1997, Wang et al., 2011) RluA-1 (Wang et al., 2011)
Alleles and Phenotypes
Causes alleles	Ecol\lacZ^E7-2-36 (Uemura et al., 1989, Brenman et al., 2001, Grueber et al., 2003, Ledent et al., 1998, Kim et al., 2006, Moore et al., 2002, Orgogozo et al., 2001, Usui-Ishihara et al., 2000, Huang et al., 2000, Brewster et al., 2001, Dye et al., 1998, Brewster and Bodmer, 1995, Vervoort et al., 1995, Vervoort et al., 1997, Gautier et al., 1997, Wang et al., 2011) RluA-1^E7-2-36 (Wang et al., 2011)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter Stage Tissue/Position (including subcellular localization) Reference embryonic stage presumptive embryonic/larval peripheral nervous system \| restricted (Brewster and Bodmer, 1995) multidendritic neuron (Brewster and Bodmer, 1995) embryonic stage 15 multidendritic neuron (Huang et al., 2000) embryonic stage 16 dorsal multidendritic neuron ddaE (Grueber et al., 2003) dorsal multidendritic neuron ddaD (Grueber et al., 2003) abdominal dorsal bipolar neuron dbp (Grueber et al., 2003) lateral multidendritic neuron ldaA (Grueber et al., 2003) lateral multidendritic neuron ldaB (Grueber et al., 2003) abdominal anterior ventral multidendritic neuron vdaa (Grueber et al., 2003) abdominal ventral multidendritic neuron v'dap (Grueber et al., 2003) ventral multidendritic neuron vdaA (Grueber et al., 2003) ventral multidendritic neuron vdaB (Grueber et al., 2003) ventral multidendritic neuron vdaC (Grueber et al., 2003) ventral multidendritic neuron vdaD (Grueber et al., 2003) abdominal ventral bipolar neuron vbp (Grueber et al., 2003) abdominal posterior ventral multidendritic neuron vdap (Grueber et al., 2003) embryonic stage 16 -- third instar larval stage dorsal multidendritic neuron ddaA (Grueber et al., 2003) dorsal multidendritic neuron ddaB (Grueber et al., 2003) dorsal multidendritic neuron ddaC (Grueber et al., 2003) dorsal multidendritic neuron ddaD (Grueber et al., 2003)
Additional Information
Statement Reference In embryos, expressed in all multidendritic (type II) neurons in the PNS. (Brewster and Bodmer, 1995)

Marker for	multidendritic neuron (Brewster and Bodmer, 1995)
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	E2-7-36 (Brenman et al., 2001) E7-2-36 (Wang et al., 2011) E7-2-36 lacZ (Kim et al., 2006) E7-3-36 (FlyBase, 1992-) P{lacW}E7-2-36 (FlyBase, 1992-)
Secondary FlyBase IDs

References ( 18 )
Research paper	Wang et al., 2011, Int. J. Dev. Biol. 55(2): 223--227 Spatially controlled expression of the Drosophila pseudouridine synthase RluA-1. [FBrf0213886] Kim et al., 2006, Genes Dev. 20(20): 2806--2819 The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. [FBrf0195191] Grueber et al., 2003, Cell 112(6): 805--818 Different levels of the homeodomain protein Cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons. [FBrf0157166] Moore et al., 2002, Science 297(5585): 1355--1358 hamlet, a binary genetic switch between single- and multiple- dendrite neuron morphology. [FBrf0152335] Brenman et al., 2001, Dev. Cell 1(5): 667--677 Sequoia, a tramtrack-related zinc finger protein, functions as a pan-neural regulator for dendrite and axon morphogenesis in Drosophila. [FBrf0141460] Brewster et al., 2001, Mech. Dev. 105(1-2): 57--68 The selector gene cut represses a neural cell fate that is specified independently of the Achaete-Scute-Complex and atonal. [FBrf0137018] Orgogozo et al., 2001, Development 128(5): 631--643 Lineage, cell polarity and inscuteable function in the peripheral nervous system of the Drosophila embryo. [FBrf0134574] Huang et al., 2000, Neuron 25(1): 57--67 The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system. [FBrf0126761] Usui-Ishihara et al., 2000, Dev. Biol. 225(2): 357--369 Larval multidendrite neurons survive metamorphosis and participate in the formation of imaginal sensory axonal pathways in the notum of Drosophila. [FBrf0130129] Dye et al., 1998, Development 125(10): 1845--1856 The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein. [FBrf0102830] Ledent et al., 1998, Int. J. Dev. Biol. 42(2): 163--170 Expression and function of tap in the gustatory and olfactory organs of Drosophila. [FBrf0101939] Gautier et al., 1997, Gene 191(1): 15--21 tap, a Drosophila bHLH gene expressed in chemosensory organs. [FBrf0094752] Vervoort et al., 1997, Development 124(14): 2819--2828 Genetic basis of the formation and identity of type I and type II neurons in Drosophila embryos. [FBrf0097687] Brewster and Bodmer, 1995, Development 121(9): 2923--2936 Origin and specification of type II sensory neurons in Drosophila. [FBrf0083795] Vervoort et al., 1995, Development 121(9): 3111--3120 Genetic determinants of sense organ identity in Drosophila: Regulatory interactions between cut and poxn. [FBrf0084474] Bier et al., 1989, Genes Dev. 3: 1273--1287 Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. [FBrf0049800] Uemura et al., 1989, Cell 58: 349--360 numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. [FBrf0049350]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]