Dmel\P{GawB}c135 Insertion

General Information
Symbol	Dmel\P{GawB}c135	Species	D. melanogaster
Name		FlyBase ID	FBti0002589
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Scer\GAL4	Viability / fertility	viable
Causes allele(s)	Scer\GAL4^c135	Stock availability	2 publicly available
LINE ID
Genomic Location
Chromosomal location	3	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)	3 (Hrdlicka et al., 2002)
Sequence Location
Orientation
Cytological location (computed by FlyBase)
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Scer\GAL4 (Harrison et al., 1995, Hrdlicka et al., 2002, Arya et al., 2006, Lai et al., 2012, Palgi et al., 2009, Graham et al., 2010, Adamson et al., 2011, Tran et al., 2012)
Alleles and Phenotypes
Causes alleles	Scer\GAL4^c135 (Harrison et al., 1995, Hrdlicka et al., 2002, Arya et al., 2006, Lai et al., 2012, Palgi et al., 2009, Graham et al., 2010, Adamson et al., 2011, Tran et al., 2012)

Lethality References viable (Hrdlicka et al., 2002)
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference third instar larval stage embryonic/larval digestive system (Harrison et al., 1995) Malpighian tubule (Harrison et al., 1995) embryonic/larval brain (Harrison et al., 1995) fat body (Harrison et al., 1995) trachea (Harrison et al., 1995) embryonic/larval lymph gland (Harrison et al., 1995) embryonic/larval salivary gland (Harrison et al., 1995) optic lobe (Harrison et al., 1995) adult stage neuron \| subset of adult brain (Lai et al., 2012) antennal mechanosensory and motor center B1a projection neuron (Lai et al., 2012)
Additional Information
Statement Reference Expression during embryogenesis has not yet been described. However, when used to drive expression of UAS constructs that are usually lethal when expressed in embryos, animals can be recovered. This suggests there is little or no embryonic expression. (Perrimon, 1997.6.4) Expression in the lymph gland is uniform. (Harrison et al., 1995)

Marker for	antennal mechanosensory and motor center B1a projection neuron (Lai et al., 2012)
Reflects expression of
Reporter construct used in assay	Mmus\Cd8a^{Scer\UAS.T:Avic\GFP} (Lai et al., 2012)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 2 )
Bloomington	6978 w¹¹¹⁸; P{GawB}c135
Kyoto	108995 w¹¹¹⁸; P{GawB}c135
Linkouts
Comments
	Generated by K. Kaiser. (Perrimon, 1997.6.4) When directing expression of P{UAS-hop.Tum} or P{UAS-hop.H}, capable of producing melanotic tumors in larvae. (Harrison et al., 1995)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	c135 (Harrison et al., 1995, Tran et al., 2012) C135 (Arya et al., 2006) C135c135-Gal4 (Hrdlicka et al., 2002) C135-GAL4 (Palgi et al., 2009) c135-GAL4 (Graham et al., 2010) C135-Gal4 (Adamson et al., 2011) E0583-Gal4 (Lai et al., 2012) P{GawB}C135 (Perrimon, 1997.6.4) P{GawB}c135 (FlyBase, 1992-) w¹¹¹⁸;P{w^+mW.hs=GawB}c135 (Lai et al., 2012)
Secondary FlyBase IDs

References ( 11 )
Research paper	Lai et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(7): 2607--2612 Auditory circuit in the Drosophila brain. [FBrf0217491] Tran et al., 2012, J. Biol. Chem. 287(8): 5243--5252 Multiple Members of the UDP-GalNAc: Polypeptide N-Acetylgalactosaminyltransferase Family Are Essential for Viability in Drosophila. [FBrf0217507] Adamson et al., 2011, Genetics 189(2): 495--506 A Drosophila model for genetic analysis of influenza viral/host interactions. [FBrf0216397] Graham et al., 2010, J. Biol. Chem. 285(15): 11143--11153 Neurologic dysfunction and male infertility in Drosophila porin mutants: a new model for mitochondrial dysfunction and disease. [FBrf0210435] Palgi et al., 2009, Proc. Natl. Acad. Sci. U.S.A. 106(7): 2429--2434 Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons. [FBrf0206690] Arya et al., 2006, Genetics 174(1): 125--134 Molecular characterization of teflon, a gene required for meiotic autosome segregation in male Drosophila melanogaster. [FBrf0194210] Hrdlicka et al., 2002, genesis 34(1-2): 51--57 Analysis of twenty-four Gal4 lines in Drosophila melanogaster. [FBrf0152376] Harrison et al., 1995, EMBO J. 14(12): 2857--2865 Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. [FBrf0082087] Brand and Perrimon, 1993, Development 118(2): 401--415 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
Personal communication to FlyBase	Perrimon, 1997.6.4, FBrf0093306, pc from N. Perrimon. FBrf0093306, pc from N. Perrimon. [FBrf0093306]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]