FlyBase Insertion Report: Dmel\P{GawB}E132

Drives expression in the distal-most part of the wing disc; in a lateral stripe in the outer optic anlage and in the lamina furrow in the eye disc; in polar follicle cells during oogenesis and in hub cells during spermatogenesis; and in DN period neurons in the adult brain. Also can be used as a read-out for activation of the JAK/STAT pathway.

(FlyBase Curators, 2017)

At 48 hours, upd1 reporter is expressed broadly in the presumptive pouch, hinge and the lateral part of the notum. It is excluded from the medial notum and the peripodial epithelium. At 60 hr, expression is down-regulated in the distal pouch and notum. At 96-120 hr, expression is restricted to the lateral border of the notum. bowl and upd1 reporter are expressed in adjacent domains along the anterior margin in an interlocking pattern.

(Hatini et al., 2013)

ScerGAL4^upd1-E132 drives expression in small-nucleated progenitors to enterocytes (e.g., intestinal stem cells and enteroblasts).

(Osman et al., 2012)

ScerGAL4^upd-E132 drives expression in a widespread pattern in the adult brain, including the DN clock neurons and some lateral located neurons. Dendrites of both of these neuron clusters are located near the projections of the PDF positive sLNV clock neurons.

(Luo and Sehgal, 2012)

upd1-GAL4-expressing neurons comprise a subset of mushroom body alph/beta and gamma neurons. These neurons are organized into four distinct bundles, visible within the mushroom body peduncle. The four upd1 axon tracts initally enter the peduncle separately, but fuse into two final bundles at a more anterior level. upd1-expressing neurons represent a subset of alpha/beta and gamma neurons.

(Copf et al., 2011)

ScerGAL4^upd-E132 drives expression in a stripe of cells along the most-lateral edge of the larval outer optic anlage and then becomes localized in the lamina furrow after the furrow forms around mid-third instar.

(Wang et al., 2011)

In second instar larva, expression throughout much of the ventral region of the eye-antennal disc, with staining expanding posteriorly to cover the entire dorsoventral extent of the eye disc. In third instar larva, expression in the antennal disc and in a small patch of cells at the posterior of the eye disc near the optic stalk.

(Pignoni and Zipursky, 1997)

Marker for

hub cell

(Voog et al., 2008)

Reflects expression of

upd1

(Recasens-Alvarez et al., 2017, Luo and Sehgal, 2012, Osman et al., 2012, Copf et al., 2011, Wang et al., 2011, Voog et al., 2008, Assa-Kunik et al., 2007, Bardot et al., 2002)

Reporter construct used in assay

Avic\GFP^S65T.UAS

(Voog et al., 2008)

Avic\GFP^UAS.cUa

(Osman et al., 2012)

Data on Genetic Line

Line ID

Origin as a multiple insertion line

Progenitor(s) within the Genome

Related Aberration or Balancer

Aberration

Balancer

Stocks (1)

Bloomington

26796

P{GawB}E132, w^*

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (23)

Reported As

Symbol Synonym

E132

(Tsai and Sun, 2004)

E132 Gal4

(Collier et al., 2004)

E132-GAL4

(Tsai et al., 2007, Lim et al., 2005, Jang et al., 2003, Seimiya and Gehring, 2000)

E132-Gal4

(Höhne et al., 2025, Rötte et al., 2024, Hétié et al., 2014, Ma et al., 2014, Wright et al., 2011, Porsch et al., 2005, Reynolds-Kenneally and Mlodzik, 2005)

E132:Gal4

(Kozopas and Nusse, 2002)

E132Gal4

(Voog et al., 2014)

GAL4 E132 line

(Halder et al., 1995)

GAL4-E132

(Kim et al., 1996)

P{GawB}E132

(Miao et al., 2022, FlyBase, 1992-)

P{upd-gal4}

(Wu et al., 2016)

Upd(E132)-GAL4

(Luo and Sehgal, 2012)

Upd-GAL4

(Hatini et al., 2013, Luo and Sehgal, 2012)

Upd-Gal4

(Miao et al., 2022, Yu et al., 2016, Assa-Kunik et al., 2007, Bastock and Strutt, 2007)

UpdGal4

(Vachias et al., 2010)

upd-GAL4

(Ku et al., 2023, Herrera et al., 2021, Toledano et al., 2012, Copf et al., 2011, Ngo et al., 2010, Bach et al., 2007)

upd-GAL4^E132

(Contreras et al., 2018)

upd-Gal4

(Höhne et al., 2025, van Nierop Y Sanchez et al., 2025, Vida et al., 2025, Rötte et al., 2024, Grmai et al., 2018, Levings and Nakato, 2018, Manning et al., 2017, Tarayrah et al., 2015, Yu et al., 2015, Hétié et al., 2014, Pitsouli and Perrimon, 2013, Gutierrez-Aviño et al., 2009)

upd-gal4

(Chen et al., 2018, Recasens-Alvarez et al., 2017, Inaba et al., 2015, Vachias et al., 2010, Evans et al., 2009, Evans et al., 2009)

upd1-Gal4

(Osman et al., 2012)

upd1-gal4

(Recasens-Alvarez et al., 2017)

upd^E132-GAL4

(Cao et al., 2022)

updGAL4

(Voog et al., 2008)

updGal4

(Ladyzhets et al., 2020, Voog et al., 2014)

Name Synonyms

Secondary FlyBase IDs

References (61)

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