A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{PZ}drk10626 Insertion

General Information
Symbol Dmel\P{PZ}drk10626 Species D. melanogaster
Name FlyBase ID FBti0002945
Feature type transposable_element_insertion_site
Description
Inserted element P{PZ} Expression data lacZ reporter
Affected gene(s) drk, Ecol\lacZ Viability / fertility
Causes allele(s) drk10626, Ecol\lacZdrk-10626 Stock availability 1 publicly available
LINE ID l(2)10626
Genomic Location
Chromosomal location 2R ( 50A13 ) Sequence location 2R:9,389,591..9,389,591 [+]
Map ( GBrowse ) detailed view FBti0035204 FBti0026136 FBti0124366 FBti0108761 FBti0110363 FBti0143755 FBti0026183 FBti0103948 FBti0110034 FBti0006422 FBti0002945 FBti0110961 FBti0103395 FBti0100150 FBti0104871 FBti0108707 FBti0023115 FBti0103102 FBti0107177 FBti0011166 FBti0125155_2 FBti0125155_1 FBti0042687 FBti0026403 FBti0011088 FBti0007640 FBti0105146 FBti0023458 FBti0039937 FBti0104001 FBti0026236 FBti0009939 FBti0033315 FBti0126602
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Description
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
2R:9,389,591..9,389,591 [+]
Orientation
Cytological location
(computed by FlyBase)
50A13 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
50A12-50A14 (in situ hybridization reported)
(BDGP Project Members, 1994-1999)
Comments concerning
location
hide Sequence Data
Flanking sequence
G00788
(FlyBase, 1992-,  
hide Inserted Element
Construct P{PZ}
Location-dependent
role
lacZ enhancer trap
(Mlodzik and Hiromi, 1992)
Size 14.545Kb
Associated alleles
Ecol\lacZP\T.PZ
l(3)87Df7.2
ry+t7.2
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
drk
(Heuer et al., 1995, Moressis et al., 2009)
Ecol\lacZ
(BDGP Project Members, 1994-1999, Jackle and Janning, 1998.8.10, Vosshall, 1998.8.10)
hide Alleles and Phenotypes
Causes alleles
drk10626
(Heuer et al., 1995, BDGP Project Members, 1994-1999, Simon et al., 1993, Spradling et al., 1999, Moressis et al., 2009)
Ecol\lacZdrk-10626
(BDGP Project Members, 1994-1999, Jackle and Janning, 1998.8.10, Vosshall, 1998.8.10)
Lethality
References
lethal | embryonic stage | fully | rescuable maternal effect
(Perrimon et al., 1996)
lethal | larval stage | recessive
(Perrimon et al., 1996)
lethal | recessive
(Simon et al., 1993, Spradling et al., 1999)
Sterility
References
hide Phenotype Manifest In
abdomen | posterior
(Perrimon et al., 1996)
embryonic/first instar larval cuticle
(Perrimon et al., 1996)
head
(Perrimon et al., 1996)
hide Detailed Description
Statement
Reference
Olfactory association learning is lower in drk[10626] heterozygotes compared to controls.
(Moressis et al., 2009)
Germline clones produce eggs with patterning defects: defects in both head and tail regions.
(Perrimon et al., 1996)
hide Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage  
embryonic/larval midgut  
(Jackle and Janning, 1998.8.10)
embryonic/larval foregut  
(Jackle and Janning, 1998.8.10)
embryonic/larval brain | presumptive  
(Jackle and Janning, 1998.8.10)
epidermis  
(Jackle and Janning, 1998.8.10)
presumptive embryonic/larval central nervous system | restricted  
(Jackle and Janning, 1998.8.10)
Malpighian tubule  
(Jackle and Janning, 1998.8.10)
embryonic/larval hindgut  
(Jackle and Janning, 1998.8.10)
amnioserosa  
(Jackle and Janning, 1998.8.10)
presumptive embryonic/larval peripheral nervous system | restricted  
(Jackle and Janning, 1998.8.10)
mesoderm  
(Jackle and Janning, 1998.8.10)
wandering third instar larval stage  
gastric caecum  
(Meister and Braun, 1995.10)
embryonic/larval hindgut  
(Meister and Braun, 1995.10)
imaginal disc  
(Meister and Braun, 1995.10)
gonad  
(Meister and Braun, 1995.10)
embryonic/larval midgut  
(Meister and Braun, 1995.10)
embryonic/larval fat body  
(Meister and Braun, 1995.10)
embryonic/larval salivary gland  
(Meister and Braun, 1995.10)
Malpighian tubule  
(Meister and Braun, 1995.10)
Additional Information
Statement
Reference
In embryo, expression in Malpighian tubules uncertain.
(Jackle and Janning, 1998.8.10)
In third instar larva, expression in fat body very weak.
(Meister and Braun, 1995.10)
Marker for
Reflects
expression of
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
l(2)10626
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
12378
P{PZ}drk10626 cn1/CyO; ry506
hide Linkouts
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
drk10626
(Moressis et al., 2009)
drkP1
(Moressis et al., 2009)
P2378
(Meister and Braun, 1995.10)
P{PZ}drk10626
(FlyBase, 1992-)
P{PZ}l(2)1062610626
(FlyBase, 1992-)
P{ry+t7.2=PZ}drk10626
(FlyBase, 1992-)
Secondary FlyBase IDs
  • FBti0000226
hide References ( 14 )
Research paper
Moressis et al., 2009, J. Neurosci. 29(8): 2611--2625
A dual role for the adaptor protein DRK in Drosophila olfactory learning and memory. [FBrf0207513]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
Spradling et al., 1999, Genetics 153(1): 135--177
The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Vaizel-Ohayon and Schejter, 1999, Curr. Biol. 9(16): 889--898
Mutations in centrosomin reveal requirements for centrosomal function during early Drosophila embryogenesis. [FBrf0111509]
Perrimon et al., 1996, Genetics 144(4): 1681--1692
Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. [FBrf0091142]
Heuer et al., 1995, Development 121(11): 3861--3876
The Drosophila homeotic target gene centrosomin, cnn, encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis. [FBrf0084021]
Simon et al., 1993, Cell 73(1): 169--177
An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro. [FBrf0057898]
Mlodzik and Hiromi, 1992, Conn, 1992: 397--414
Enhancer trap method in Drosophila: its application to neurobiology. [FBrf0066714]
Personal communication to FlyBase
Jackle and Janning, 1998.8.10, Patterns of lacZ expression.
Patterns of lacZ expression. [FBrf0103143]
Vosshall, 1998.8.10, Patterns of lacZ expression.
Patterns of lacZ expression. [FBrf0103142]
Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington.
lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714]
FlyBase analysis
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]
BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0067338]