Dmel\P{lArB}disco^rH219 Insertion

General Information
Symbol	Dmel\P{lArB}disco^rH219	Species	D. melanogaster
Name		FlyBase ID	FBti0003119
Feature type	transposable_element_insertion_site
Description
Inserted element	P{lArB}	Expression data	lacZ reporter
Affected gene(s)	disco, Ecol\lacZ	Viability / fertility
Causes allele(s)	disco^rH219, Ecol\lacZ^disco-rH219	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	X ( 14B3 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
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FB2013_03
FB2013_02
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Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	14B3 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{lArB}
Location-dependent role	lacZ enhancer trap (Wilson et al., 1989)
Size	18.327Kb
Associated alleles	Adh^+t3.2 Ecol\lacZ^P\T.A92a ry^+t7.2
Molecular map
Affected Gene(s)
Insertion may affect gene	disco (Heilig et al., 1991) Ecol\lacZ (Heilig et al., 1991, Mirth and Akam, 2002, Bishop et al., 1999, Mirth, 2005, Cohen et al., 1991)
Alleles and Phenotypes
Causes alleles	disco^rH219 (Heilig et al., 1991, Cohen et al., 1991) Ecol\lacZ^disco-rH219 (Heilig et al., 1991, Mirth and Akam, 2002, Bishop et al., 1999, Mirth, 2005, Cohen et al., 1991)

Lethality References viable (Cohen et al., 1991)
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter Stage Tissue/Position (including subcellular localization) Reference larval stage ventral thoracic disc \| restricted (Mirth and Akam, 2002) pupal stage joint (Mirth and Akam, 2002) leg \| restricted (Mirth and Akam, 2002)
Additional Information
Statement Reference In third instar and early pupal leg disc, expressed in rings in the distal leg, with fainter expression in proximal leg. In mid-pupal stages, expressed throughout the joints of the tibia and tarsi. (Mirth and Akam, 2002)

Marker for
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	disco-lacZ (Bishop et al., 1999) disconnected lacz (Mirth, 2005) disconnected lacZ (Mirth and Akam, 2002) P{lArB}disco^rH219 (Heilig et al., 1991, FlyBase, 1992-)
Secondary FlyBase IDs

References ( 7 )
Research paper	Mirth, 2005, Dev. Biol. 278(1): 163--174 Ecdysteroid control of metamorphosis in the differentiating adult leg structures of Drosophila melanogaster. [FBrf0183220] Mirth and Akam, 2002, Dev. Biol. 246(2): 391--406 Joint development in the Drosophila leg: cell movements and cell populations. [FBrf0148940] Bishop et al., 1999, Development 126(13): 2993--3003 Composite signalling from Serrate and establishes leg segments in Drosophila through Notch. [FBrf0108607] Cohen et al., 1991, Mech. Dev. 33: 229--240 Early development of leg and wing primordia in the Drosophila embryo. [FBrf0054617] Heilig et al., 1991, EMBO J. 10: 809--815 Isolation and characterization of the disconnected gene of Drosophila melanogaster. [FBrf0053902] Wilson et al., 1989, Genes Dev. 3(9): 1301--1313 P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila. [FBrf0049802]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{lArB}discorH219 Insertion

Dmel\P{lArB}disco^rH219 Insertion