Dmel\P{GawB}pnr^MD237 Insertion

General Information
Symbol	Dmel\P{GawB}pnr^MD237	Species	D. melanogaster
Name		FlyBase ID	FBti0004011
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	pnr, Scer\GAL4	Viability / fertility
Causes allele(s)	pnr^MD237, Scer\GAL4^pnr-MD237	Stock availability	3 publicly available
LINE ID
Genomic Location
Chromosomal location	3R ( 89A13-89B1 )	Sequence location
Recent Updates
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FB2011_10	References Rebeiz et al., 2011, Development 138(2): 215--225 Sekine et al., 2011, J. Cell Sci. 124(17): 3006--3016
FB2012_01	References Umehara et al., 2010, Molec. Cell. Biochem. 342(1-2): 223--232 Chen et al., 2010, Science 330(6011): 1682--1685 Tripura et al., 2011, Int. J. Dev. Biol. 55(6): 583--590
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	89A13-89B1 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	pnr (Calleja, 1996.10.16) Scer\GAL4 (Jeong et al., 2008, de Navascués and Modolell, 2007, Mummery-Widmer et al., 2009, Tue et al., 2011, Eid et al., 2008, Dolezelova et al., 2007, Shalaby et al., 2009, Cerrato et al., 2006, Heitzler et al., 1996, Collins et al., 1999, Gritzan et al., 2002, Giordano et al., 2002, Herranz and Morata, 2001, Dworak et al., 2001, Ryoo et al., 1999, Wildonger and Mann, 2005, True et al., 1999, Singh et al., 2005, Renaud and Simpson, 2001, Ramet et al., 2002, Giagtzoglou et al., 2005, Heitzler et al., 2003, Takahashi et al., 2005, Vanolst et al., 2005, Zhang et al., 2001, Wittkopp et al., 2002, Raymond et al., 2001, Pena-Rangel et al., 2002, Katanaev and Tomlinson, 2006, Szuplewski et al., 2003, Ghazi et al., 2003, Gubb et al., 1999, Guo et al., 1999, Wulbeck and Simpson, 2002, Simpson, 2006, Giagtzoglou et al., 2003, Schock and Perrimon, 2002, Renaud and Simpson, 2002, Reichhart et al., 2002, Presente et al., 2002, Price et al., 2002, Geisbrecht and Montell, 2004, Ryoo et al., 2002, Baena-Lopez and Garcia-Bellido, 2003, Calleja et al., 2000, Singh and Choi, 2003, Ahmed et al., 2003, Ghazi et al., 2000, Takatsu et al., 2000, Nagel et al., 2000, Kopp et al., 2000, Ramain et al., 2000, Usui and Simpson, 2000, Martin-Blanco et al., 2000, Guo et al., 2000, Zaffran and Frasch, 2000, Tomoyasu et al., 2000, Maurel-Zaffran and Treisman, 2000, Fernandez et al., 2000, Culi et al., 2001, Schock and Perrimon, 2000, Zeitlinger and Bohmann, 1999, Helms et al., 1999, Sawamoto et al., 1999, Zecchini et al., 1999, Sato et al., 1999, Haenlin et al., 1997, Escudero et al., 2005, Cubadda et al., 1997, Miskolczi-McCallum et al., 2005, Riesgo-Escovar and Hafen, 1997, Pichaud and Casares, 2000, Ishimaru et al., 2004, Jindra et al., 2004, Ishimaru et al., 2004, Usui-Ishihara and Simpson, 2005, Mihaly et al., 2001, Calleja, 1996.10.16, Bernardoni et al., 1998, Reed et al., 2001, Chandra et al., 2003, Boettner et al., 2003, Hou et al., 1997, Pallavi and Shashidhara, 2003, Aldaz et al., 2003, Casares et al., 1996, Calleja et al., 1996, Villa-Cuesta et al., 2003, Seugnet et al., 1997, Apidianakis et al., 1999, Biryukova and Heitzler, 2005, Alexander et al., 2006, True et al., 2005, Ekas et al., 2006, Uhlirova and Bohmann, 2006, Polaski et al., 2006, Dietzl et al., 2007, Schimmelpfeng et al., 2006, Joza et al., 2008, Moores et al., 2008, Norgate et al., 2006, Yoshioka et al., 2008, Lee et al., 2006, Flaherty et al., 2009, Fujiyama-Nakamura et al., 2009, Southon et al., 2008, Morris et al., 2006, Tuxworth et al., 2009, Biryukova and Heitzler, 2008, Rousset et al., 2010, Barrio et al., 2007, Wittkopp et al., 2009, Hamel et al., 2010, Garlena et al., 2010, Guichard et al., 2006, Asmar et al., 2008, Nagai et al., 2010, Bolinger et al., 2010, Binks et al., 2010, Bronstein et al., 2010, Gaumer et al., 2000, de Navascués and Modolell, 2010, Olguín et al., 2011, Xue et al., 2007, Olguín et al., 2011, Rauskolb et al., 2011, Sekine et al., 2011, Rebeiz et al., 2011, Tripura et al., 2011, Umehara et al., 2010, Chen et al., 2010)
Alleles and Phenotypes
Causes alleles	pnr^MD237 (Calleja, 1996.10.16, Gibert et al., 2005, Pena-Rangel et al., 2002, Ghazi et al., 2003, Wulbeck and Simpson, 2002, Ramain et al., 2000, Tomoyasu et al., 2000, Escudero et al., 2005, Heitzler et al., 1996, Calleja et al., 1996) Scer\GAL4^pnr-MD237 (Heitzler et al., 1996, Collins et al., 1999, Jeong et al., 2008, de Navascués and Modolell, 2007, Gritzan et al., 2002, Mummery-Widmer et al., 2009, Tue et al., 2011, Giordano et al., 2002, Herranz and Morata, 2001, Dworak et al., 2001, Ryoo et al., 1999, Wildonger and Mann, 2005, True et al., 1999, Singh et al., 2005, Renaud and Simpson, 2001, Ramet et al., 2002, Giagtzoglou et al., 2005, Heitzler et al., 2003, Takahashi et al., 2005, Vanolst et al., 2005, Zhang et al., 2001, Wittkopp et al., 2002, Raymond et al., 2001, Pena-Rangel et al., 2002, Katanaev and Tomlinson, 2006, Szuplewski et al., 2003, Ghazi et al., 2003, Gubb et al., 1999, Guo et al., 1999, Wulbeck and Simpson, 2002, Simpson, 2006, Giagtzoglou et al., 2003, Schock and Perrimon, 2002, Renaud and Simpson, 2002, Reichhart et al., 2002, Presente et al., 2002, Price et al., 2002, Geisbrecht and Montell, 2004, Ryoo et al., 2002, Baena-Lopez and Garcia-Bellido, 2003, Calleja et al., 2000, Eid et al., 2008, Singh and Choi, 2003, Ahmed et al., 2003, Ghazi et al., 2000, Takatsu et al., 2000, Nagel et al., 2000, Kopp et al., 2000, Ramain et al., 2000, Usui and Simpson, 2000, Martin-Blanco et al., 2000, Guo et al., 2000, Zaffran and Frasch, 2000, Tomoyasu et al., 2000, Maurel-Zaffran and Treisman, 2000, Fernandez et al., 2000, Culi et al., 2001, Schock and Perrimon, 2000, Zeitlinger and Bohmann, 1999, Helms et al., 1999, Sawamoto et al., 1999, Zecchini et al., 1999, Sato et al., 1999, Haenlin et al., 1997, Escudero et al., 2005, Cubadda et al., 1997, Miskolczi-McCallum et al., 2005, Riesgo-Escovar and Hafen, 1997, Pichaud and Casares, 2000, Ishimaru et al., 2004, Jindra et al., 2004, Ishimaru et al., 2004, Usui-Ishihara and Simpson, 2005, Mihaly et al., 2001, Calleja, 1996.10.16, Bernardoni et al., 1998, Reed et al., 2001, Chandra et al., 2003, Boettner et al., 2003, Hou et al., 1997, Pallavi and Shashidhara, 2003, Aldaz et al., 2003, Casares et al., 1996, Calleja et al., 1996, Villa-Cuesta et al., 2003, Seugnet et al., 1997, Apidianakis et al., 1999, Biryukova and Heitzler, 2005, Alexander et al., 2006, True et al., 2005, Dolezelova et al., 2007, Shalaby et al., 2009, Cerrato et al., 2006, Ekas et al., 2006, Uhlirova and Bohmann, 2006, Polaski et al., 2006, Dietzl et al., 2007, Schimmelpfeng et al., 2006, Joza et al., 2008, Moores et al., 2008, Norgate et al., 2006, Yoshioka et al., 2008, Lee et al., 2006, Flaherty et al., 2009, Fujiyama-Nakamura et al., 2009, Southon et al., 2008, Morris et al., 2006, Tuxworth et al., 2009, Biryukova and Heitzler, 2008, Rousset et al., 2010, Barrio et al., 2007, Wittkopp et al., 2009, Hamel et al., 2010, Garlena et al., 2010, Guichard et al., 2006, Asmar et al., 2008, Nagai et al., 2010, Bolinger et al., 2010, Binks et al., 2010, Bronstein et al., 2010, Gaumer et al., 2000, de Navascués and Modolell, 2010, Olguín et al., 2011, Xue et al., 2007, Olguín et al., 2011, Rauskolb et al., 2011, Sekine et al., 2011, Rebeiz et al., 2011, Tripura et al., 2011, Umehara et al., 2010, Chen et al., 2010)

Lethality References viable (Heitzler et al., 1996)
Sterility References
Phenotype Manifest In
	adult thorax \| dorsal (Pena-Rangel et al., 2002) anterior vertical bristle (Heitzler et al., 1996) chaeta (Pena-Rangel et al., 2002) dorsal medial muscle (Ghazi et al., 2003) dorsocentral bristle (Escudero et al., 2005, Calleja et al., 1996) dorsocentral bristle \| ectopic (Ghazi et al., 2003) head (Heitzler et al., 1996) macrochaeta (Heitzler et al., 1996) mesothoracic cleft (Heitzler et al., 1996) mesothoracic tergum (Ghazi et al., 2003) postvertical bristle (Heitzler et al., 1996, Pena-Rangel et al., 2002) scutellar bristle (Escudero et al., 2005)
Detailed Description
Statement Reference The slight increase in lymph gland size seen in Zfrp8[SM206]/+ larvae is dominantly suppressed by pnr[MD237]. The increase in lymph gland size seen in homozygous Zfrp8[SM206] larvae is significantly dominantly suppressed by pnr[MD237]. (Minakhina et al., 2007) pnr^MD237/pnr^V1 flies show loss of dorsocentral and scutellar macrochaetae. (Escudero et al., 2005) pnr^MD237/pnr^D1 mutants show abnormal muscle attachments. The dorsal medial muscle (DLM)s appear as a single fibre. The notum also shows defects, a notal cleft is seen along with extra dorsocentral bristles. (Ghazi et al., 2003) pnr^MD237/+ adults expressing EP344^EP344 under the control of Scer\GAL4^pnr-MD237 have short macrochaetae. pnr^MD237/+ adults expressing EP1051^EP1051 under the control of Scer\GAL4^pnr-MD237 have deformed scutellar macrochaetae. pnr^MD237/+ adults expressing l(2)k10113^EP1221 under the control of Scer\GAL4^pnr-MD237 show loss of dorsocentral macrochaetae and microchaetae. pnr^MD237/+ adults expressing CG3600^EP1232 under the control of Scer\GAL4^pnr-MD237 show loss of some macrochaetae and microchaetae. pnr^MD237/+ adults expressing NFAT^EP1353 under the control of Scer\GAL4^pnr-MD237 show loss of microchaetae and deformed scutellar macrochaetae. pnr^MD237/+ adults expressing sd^EP1435 under the control of Scer\GAL4^pnr-MD237 show loss of several microchaetae and dorsocentral macrochaetae. pnr^MD237/+ adults expressing Mef2^EP2002a under the control of Scer\GAL4^pnr-MD237 show loss of a row of microchaetae in the dorsal midline. pnr^MD237/+ adults expressing l(2)05510^EP2356 under the control of Scer\GAL4^pnr-MD237 show loss of macrochaetae and microchaetae in the dorsal midline. pnr^MD237/+ adults expressing l(2)05510^EP2586 under the control of Scer\GAL4^pnr-MD237 show loss of macrochaetae and microchaetae in the dorsal midline. pnr^MD237/+ adults expressing Myd88^EP2535 under the control of Scer\GAL4^pnr-MD237 have deformed macrochaetae. pnr^MD237/+ adults expressing EP2619^EP2619 under the control of Scer\GAL4^pnr-MD237 have microchaetae without polarity. pnr^MD237/+ adults expressing CG8219^EP3072 under the control of Scer\GAL4^pnr-MD237 show loss of a row of microchaetae in the dorsal midline. pnr^MD237/+ adults expressing CG5180^EP3073 under the control of Scer\GAL4^pnr-MD237 show loss of several dorsocentral microchaetae. pnr^MD237/+ adults expressing EP3087^EP3087, emc^EP3620, emc^EP3614, emc^EP415 or emc^EP3166 under the control of Scer\GAL4^pnr-MD237 show complete loss of dorsocentral and scutellar macrochaetae and microchaetae in the dorsal midline including the abdomen. pnr^MD237/+ adults expressing stg^EP3261 or stg^EP3426 under the control of Scer\GAL4^pnr-MD237 show loss of dorsocentral macrochaetae and several microchaetae. Some macrochaetae are short. pnr^MD237/+ adults expressing EP3306^EP3306 under the control of Scer\GAL4^pnr-MD237 show loss of dorsocentral macrochaetae and several microchaetae. pnr^MD237/+ adults expressing glec^EP3449 under the control of Scer\GAL4^pnr-MD237 show loss of scutellar macrochaetae and frequent loss of dorsocentral macrochaetae. pnr^MD237/+ adults expressing EP3621^EP3621 under the control of Scer\GAL4^pnr-MD237 show loss of dorsocentral and scutellar macrochaetae and loss of microchaetae. pnr^MD237/+ adults expressing EP443^EP443, CG33967^EP666, BEST:RE60986^EP853, EP1236^EP1236, EP2433^EP2433 or EP3060^EP3060 under the control of Scer\GAL4^pnr-MD237 have a reduced scutellum. pnr^MD237/+ adults expressing EP707^EP707, P{EP}smo^EP1220, EP1246^EP1246, EP1340^EP1340, EP1350^EP1350, EP2419^EP2419, Atx2^EP3145, Dad^EP3196 or CG31176^EP3662 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum. pnr^MD237/+ adults expressing Lig4^EP385 or ptc^EP941 under the control of Scer\GAL4^pnr-MD237 do not form a scutellum. pnr^MD237/+ adults expressing CG33967^EP666 under the control of Scer\GAL4^ap-md544 have a slightly deformed scutellum. pnr^MD237/+ adults expressing kis^EP563, kis^EP2240, EP1501^EP1501, EP2146a^EP2146a or EP3135^EP3135 under the control of Scer\GAL4^pnr-MD237 have a slight thoracic cleft. pnr^MD237/+ adults expressing CG5261^EP816 or tara^EP3463 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic cleft. pnr^MD237/+ adults expressing CG14959^EP3139 under the control of Scer\GAL4^pnr-MD237 have a deformed thorax. pnr^MD237/+ adults expressing EP3140^EP3140 under the control of Scer\GAL4^pnr-MD237 show overpigmentation of the dorsal midline. pnr^MD237/+ adults expressing Dsp1^EP355 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic and scutellar cleft. pnr^MD237/+ adults expressing EP374^EP374 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic cleft and lack the scutellum. pnr^MD237/+ adults expressing faf^EP381 under the control of Scer\GAL4^pnr-MD237 have a slight cleft in the abdominal dorsal midline and a reduced scutellum. pnr^MD237/+ adults expressing BEST:SD01859^EP416 under the control of Scer\GAL4^pnr-MD237 have microchaetae without polarity and a deformed scutellum. pnr^MD237/+ adults expressing D1^EP473 under the control of Scer\GAL4^pnr-MD237 have extra macrochaetae and a reduced scutellum. pnr^MD237/+ adults expressing CG5208^EP562 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and macrochaetae. pnr^MD237/+ adults expressing tou^EP622 under the control of Scer\GAL4^pnr-MD237 have strong thoracic and scutellar clefts. pnr^MD237/+ adults expressing XNP^EP635 under the control of Scer\GAL4^pnr-MD237 have strong thoracic and slight scutellar clefts. pnr^MD237/+ adults expressing BEST:SD02913^EP639, BEST:SD02913^EP2148, BEST:SD02913^EP2402 or BEST:SD02913^EP2437 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic cleft, deformed scutellum, head defects and loss of several macrochaetae and microchaetae. pnr^MD237/+ adults expressing esg^EP683 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic cleft and defects in the abdominal dorsal midline. pnr^MD237/+ adults expressing CG33967^EP747 under the control of Scer\GAL4^pnr-MD237 have a slight thoracic cleft and a reduced scutellum. pnr^MD237/+ adults expressing pum^EP883 under the control of Scer\GAL4^pnr-MD237 have a reduced scutellum and loss of dorsocentral macrochaetae. pnr^MD237/+ adults expressing EP950^EP950 under the control of Scer\GAL4^pnr-MD237 have extra dorsocentral and scutellar macrochaetae and missing microchaetae in the dorsal midline. pnr^MD237/+ adults expressing elB^EP965 under the control of Scer\GAL4^pnr-MD237 have strong thoracic and scutellar clefts. pnr^MD237/+ adults expressing MESR4^EP988 under the control of Scer\GAL4^pnr-MD237 have a slight thoracic cleft, a reduced scutellum and loss of several macrochaetae. pnr^MD237/+ adults expressing dpld^EP1050 under the control of Scer\GAL4^pnr-MD237 have extra scutellar macrochaetae and missing microchaetae in the dorsal midline. pnr^MD237/+ adults expressing EP1081^EP1081 under the control of Scer\GAL4^pnr-MD237 have a slight thoracic cleft and extra scutellar macrochaetae. pnr^MD237/+ adults expressing sd^EP1088 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic cleft. pnr^MD237/+ adults expressing EP1095^EP1095 under the control of Scer\GAL4^pnr-MD237 have extra scutellar macrochaetae. pnr^MD237/+ adults expressing EP1229^EP1229 or EP1229^EP2316 under the control of Scer\GAL4^pnr-MD237 have a slightly deformed head and scutellum and show loss of scutellar macrochaetae. pnr^MD237/+ adults expressing CG11138^EP1313 under the control of Scer\GAL4^pnr-MD237 have extra scutellar macrochaetae and missing dorsocentral macrochaetae and microchaetae in the dorsal midline. pnr^MD237/+ adults expressing Bx^EP1383 or Bx^EP1394 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and show loss or gain of dorsocentral and scutellar macrochaetae. pnr^MD237/+ adults expressing BEST:GH17330^EP1408 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and microchaetae without polarity. pnr^MD237/+ adults expressing EP1421^EP1421 under the control of Scer\GAL4^pnr-MD237 have extra and deformed macrochaetae. pnr^MD237/+ adults expressing NFAT^EP1508 under the control of Scer\GAL4^pnr-MD237 have a slight thoracic cleft, deformed macrochaetae and loss of microchaetae. pnr^MD237/+ adults expressing CG6701^EP2054 under the control of Scer\GAL4^pnr-MD237 show loss of scutellar macrochaetae and have defects in the abdominal midline. pnr^MD237/+ adults expressing EP2087^EP2087 under the control of Scer\GAL4^pnr-MD237 have deformed scutellar macrochaetae and microchaetae without polarity. pnr^MD237/+ adults expressing dpp^EP2232 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic cleft and a reduced scutellum. pnr^MD237/+ adults expressing cbt^EP2237 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum, extra scutellar macrochaetae and microchaetae missing in the dorsal midline. pnr^MD237/+ adults expressing shn^EP2359 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and extra microchaetae around the ocelli. pnr^MD237/+ adults expressing CG11166^EP2475 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and an altered number of macrochaetae and microchaetae. pnr^MD237/+ adults expressing ppo^EP2478 under the control of Scer\GAL4^pnr-MD237 show loss of macrochaetae and microchaetae on the dorsal midline and a deformed scutellum. pnr^MD237/+ adults expressing Hr39^EP2490 under the control of Scer\GAL4^pnr-MD237 have a thoracic cleft, extra scutellar macrochaetae and missing microchaetae. pnr^MD237/+ adults expressing tai^EP2630 under the control of Scer\GAL4^pnr-MD237 have a slight thoracic cleft and a deformed scutellum. pnr^MD237/+ adults expressing Gef64C^EP3035 under the control of Scer\GAL4^pnr-MD237 have deformed macrochaetae. pnr^MD237/+ adults expressing l(3)L0539^EP3083 or l(3)L0539^EP3523 under the control of Scer\GAL4^pnr-MD237 show loss of scutellar macrochaetae and have a reduced scutellum. pnr^MD237/+ adults expressing EP3263^EP3263 under the control of Scer\GAL4^pnr-MD237 have a deformed thorax and scutellum. pnr^MD237/+ adults expressing EP3283^EP3283 under the control of Scer\GAL4^pnr-MD237 have a slight thoracic cleft and a reduced scutellum. pnr^MD237/+ adults expressing ps^EP3406 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and show loss of scutellar macrochaetae. pnr^MD237/+ adults expressing Fmr1^EP3517 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and several deformed macrochaetae. pnr^MD237/+ adults expressing CtBP^EP3528 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic cleft and a deformed scutellum. pnr^MD237/+ adults expressing trx^EP3541 under the control of Scer\GAL4^pnr-MD237 have deformed scutellum and ectopic scutellar macrochaetae. pnr^MD237/+ adults expressing CG12084^EP3673 under the control of Scer\GAL4^pnr-MD237 show loss of several macrochaetae and microchaetae and have a slight thoracic cleft. pnr^MD237/+ adults expressing l(3)L4092^EP3690 under the control of Scer\GAL4^pnr-MD237 have a deformed thorax and scutellum. pnr^MD237/+ adults expressing CG5720^EP3716 under the control of Scer\GAL4^pnr-MD237 have short microchaetae without polarity, a deformed scutellum and overpigmentation in the thoracic dorsal midline. pnr^MD237/+ adults expressing EP3714^EP3714 under the control of Scer\GAL4^pnr-MD237 have extra microchaetae without polarity. Flies expressing both pnr^Scer\UAS.cHa and ppo^EP2478 under the control of Scer\GAL4^ap-md544 in a pnr^MD237/+ background show a reduction in thoracic bristles and an altered scutellum. (Pena-Rangel et al., 2002) Heterozygous adults show a very slight dorsal thoracic cleft and disorganisation of bristles, sometimes missing a few inner and postvertical bristles. (Pena-Rangel et al., 2002) pnr^MD237 flies have a slight midline cleft phenotype. (Wulbeck and Simpson, 2002) pnr^D1/pnr^MD237 mutants there is an increase in number of the wg-dependent dorsocentral bristles. (Calleja et al., 1996) Heterozygotes exhibit defects in the thoracic cleft and occasionally lack inner verticals and postverticals. Heterozygotes with Df(3R)sbd45 are semi-viable, lack bristles and occasionally show head defects. (Heitzler et al., 1996)
Expression Data
Reporter Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference third instar larval stage wing disc \| restricted (Calleja et al., 1996) pupal stage & adult stage thorax \| dorsal (Calleja et al., 1996) head \| dorsal (Calleja et al., 1996) abdomen \| dorsal (Calleja et al., 1996) cuticle \| dorsal (Calleja et al., 1996) distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference third instar larval stage salivary gland (Giagtzoglou et al., 2005) wing disc \| proximal (Giagtzoglou et al., 2005) haltere disc \| proximal (Calleja et al., 2000)
Additional Information
Statement Reference Expression in the larval third in is observed in the promixmal-most part of the presumptive notum in the wing disc, and in the salivary gland. (Giagtzoglou et al., 2005) Expression is driven in a wide dorsal stripe from the posterior head through the thorax and abdomen of larvae, pupae, and adults. In adults, the thoracic stripe is bounded on each side by the dorsocentral and postscutellar bristles. (Calleja et al., 2000) In adults, y⁺ phenotype observed in a dorsal band along the length of the body, excluding the terminalia. Observed as adult phenotype; expression assumed to be earlier. (Calleja et al., 1996)

Marker for
Reflects expression of	pnr (Calleja et al., 1996, Giagtzoglou et al., 2005)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 3 )
Bloomington	25758 P{UAS-Dcr-2.D}1, w¹¹¹⁸; P{GawB}pnr^MD237/TM3, Ser¹ 3039 y¹ w¹¹¹⁸; P{GawB}pnr^MD237/TM3, P{UAS-y.C}MC2, Ser¹
Kyoto	106796 y¹ w¹¹¹⁸; P{GawB}pnr^MD237/TM3, P{UAS-y.C}MC2, Ser¹
Linkouts
Comments
	Isolated using P{UAS-y.C} adult cuticle patterning screen; see FBrf0090484. (Calleja, 1996.10.16)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	gal4-pannier (Gubb et al., 1999) MD237 (Mummery-Widmer et al., 2009) md237pnrGAL4 (Ghazi et al., 2000) P{GawB}pnr^MD237 (Calleja, 1996.10.16, FlyBase, 1992-, Binks et al., 2010) P{GawB}pnr^md237 (FlyBase, 1992-) P{w^+mW.hs=GawB}pnr.MD237 (Reichhart et al., 2002) P{w^+mW.hs=GawB}pnr^md237 (FlyBase, 1992-) panier-Gal4 (Gaumer et al., 2000) pannier^MD237-Gal4 (Renaud and Simpson, 2001) pannier-Gal4 (Geisbrecht and Montell, 2004, Uhlirova and Bohmann, 2006, Shalaby et al., 2009) pannier-GAL4 (Wittkopp et al., 2002, Guo et al., 1999, True et al., 2005) Pannier-Gal4 (Southon et al., 2008) pnr (Morris et al., 2006, Umehara et al., 2010) pnr:Gal4 (Ryoo et al., 1999) pnr.Gal4 (Eid et al., 2008) pnr^Gal4 (Vanolst et al., 2005) pnr^GAL4 (Reed et al., 2001) pnr^MD237 (Cerrato et al., 2006, Biryukova and Heitzler, 2008) pnr^MD237-GAL4 (Chandra et al., 2003, Renaud and Simpson, 2002, Usui and Simpson, 2000) pnr^md237-GAL4 (Apidianakis et al., 1999) pnr^MD327-Gal4 (de Navascués and Modolell, 2007) pnr-G4 (Baena-Lopez and Garcia-Bellido, 2003, Garlena et al., 2010) pnrG4 (Olguín et al., 2011, Olguín et al., 2011) pnr-Gal (Southon et al., 2008) pnr-GAL4 (Giagtzoglou et al., 2005, Singh et al., 2005, Takahashi et al., 2005, Ishimaru et al., 2004, Ishimaru et al., 2004, Usui-Ishihara and Simpson, 2005, Ahmed et al., 2003, Singh and Choi, 2003, Boettner et al., 2003, Pallavi and Shashidhara, 2003, Szuplewski et al., 2003, Zhang et al., 2001, Ramet et al., 2002, Dworak et al., 2001, Kopp et al., 2000, Nagel et al., 2000, Guo et al., 2000, Takatsu et al., 2000, Maurel-Zaffran and Treisman, 2000, Zaffran and Frasch, 2000, Collins et al., 1999, Helms et al., 1999, Sawamoto et al., 1999, Zecchini et al., 1999, Mummery-Widmer et al., 2009, Ekas et al., 2006, Alexander et al., 2006, Tripura et al., 2011, Jeong et al., 2008, Polaski et al., 2006, Dietzl et al., 2007, Norgate et al., 2006, Yoshioka et al., 2008, Rebeiz et al., 2011, Rousset et al., 2010, Hamel et al., 2010, Bolinger et al., 2010, Sekine et al., 2011) pnr-Gal4 (Katanaev and Tomlinson, 2006, Wildonger and Mann, 2005, Giagtzoglou et al., 2005, Escudero et al., 2005, Jindra et al., 2004, Aldaz et al., 2003, Villa-Cuesta et al., 2003, Giagtzoglou et al., 2003, Schock and Perrimon, 2002, Ryoo et al., 2002, Price et al., 2002, Giordano et al., 2002, Herranz and Morata, 2001, Tomoyasu et al., 2000, Pichaud and Casares, 2000, Calleja et al., 2000, Schock and Perrimon, 2000, Zeitlinger and Bohmann, 1999, Sato et al., 1999, Biryukova and Heitzler, 2005, Gibert et al., 2005, de Navascués and Modolell, 2007, Xue et al., 2007, Joza et al., 2008, Moores et al., 2008, Lee et al., 2006, Flaherty et al., 2009, Shalaby et al., 2009, Tuxworth et al., 2009, Biryukova and Heitzler, 2008, Barrio et al., 2007, Wittkopp et al., 2009, Asmar et al., 2008, Bronstein et al., 2010, de Navascués and Modolell, 2010, Rauskolb et al., 2011) Pnr-Gal4 (Presente et al., 2002) pnrGal4 (Gritzan et al., 2002, Raymond et al., 2001, Simpson, 2006, Schimmelpfeng et al., 2006, Fujiyama-Nakamura et al., 2009) pnrGAL4 (Pena-Rangel et al., 2002, Guichard et al., 2006) Pnr-GAL4 (Martin-Blanco et al., 2000, Nagai et al., 2010) PnrGal4 (Fernandez et al., 2000) Pnr-gal4 (Dolezelova et al., 2007) PNR-GAL4 (Binks et al., 2010) pnr-gal4 (Tue et al., 2011)
Secondary FlyBase IDs
	FBti0002784 FBti0002817
References ( 135 )

Generate a list of	All references relating to this insertion ( 135 )

List References by type	Research paper ( 129 ) Supplementary material ( 2 ) Review ( 1 ) Personal communication to FlyBase ( 1 ) Abstract ( 1 ) FlyBase analysis ( 1 )
Recent research papers ( 16 )
	Olguín et al., 2011, Curr. Biol. 21(3): 236--242 Intertissue mechanical stress affects frizzled-mediated planar cell polarity in the Drosophila notum epidermis. [FBrf0212947] Rauskolb et al., 2011, PLoS Biol. 9(6): e1000624 Zyxin links fat signaling to the hippo pathway. [FBrf0213900] Rebeiz et al., 2011, Development 138(2): 215--225 Notch regulates numb: integration of conditional and autonomous cell fate specification. [FBrf0212636] Sekine et al., 2011, J. Cell Sci. 124(17): 3006--3016 p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors. [FBrf0215011] Tripura et al., 2011, Int. J. Dev. Biol. 55(6): 583--590 Regulation and activity of JNK signaling in the wing disc peripodial membrane during adult morphogenesis in Drosophila. [FBrf0216296] Tue et al., 2011, Gene 473(1): 1--7 NF-Y transcriptionally regulates the Drosophila p53 gene. [FBrf0212943] Binks et al., 2010, J. Biol. Inorg. Chem. 15(4): 621--628 Tissue-specific interplay between copper uptake and efflux in Drosophila. [FBrf0210589] Bolinger et al., 2010, Dev. Dyn. 239(7): 2078--2093 Specific isoforms of drosophila shroom define spatial requirements for the induction of apical constriction. [FBrf0211136] Bronstein et al., 2010, PLoS Genet. 6(8): e1001063 Transcriptional regulation by CHIP/LDB complexes. [FBrf0211594] Chen et al., 2010, Science 330(6011): 1682--1685 New genes in Drosophila quickly become essential. [FBrf0212650] de Navascués and Modolell, 2010, Mech. Dev. 127(9-12): 393--406 The pronotum LIM-HD gene tailup is both a positive and a negative regulator of the proneural genes achaete and scute of Drosophila. [FBrf0212072] Garlena et al., 2010, J. Cell Sci. 123(18): 3177--3188 Regulation of mixed-lineage kinase activation in JNK-dependent morphogenesis. [FBrf0211702] Hamel et al., 2010, J. Cell Biol. 188(4): 581--594 Notch ligand activity is modulated by glycosphingolipid membrane composition in Drosophila melanogaster. [FBrf0210025] Nagai et al., 2010, Exp. Cell Res. 316(2): 272--285 Syntrophin-2 is required for eye development in Drosophila. [FBrf0209384] Rousset et al., 2010, Development 137(13): 2177--2186 The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis. [FBrf0211045] Umehara et al., 2010, Molec. Cell. Biochem. 342(1-2): 223--232 Over-expression of transglutaminase in the Drosophila eye imaginal disc induces a rough eye phenotype. [FBrf0211642] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...

Dmel\P{GawB}pnrMD237 Insertion

Dmel\P{GawB}pnr^MD237 Insertion