Dmel\P{GawB}Meltrin^c768 Insertion

General Information
Symbol	Dmel\P{GawB}Meltrin^c768	Species	D. melanogaster
Name		FlyBase ID	FBti0004465
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Meltrin, Scer\GAL4	Viability / fertility
Causes allele(s)	Meltrin^c768, Scer\GAL4^c768	Stock availability	2 publicly available
LINE ID
Genomic Location
Chromosomal location	3R ( 88C10-88D2 )	Sequence location	3R:10,466,897..10,566,896
Map ( GBrowse )
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location	3R:10,466,897..10,566,896 (Skora and Spradling, 2010)
Orientation
Cytological location (computed by FlyBase)	88C10-88D2 ( inferred by FlyBase from sequence location )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Meltrin (Skora and Spradling, 2010) Scer\GAL4 (Manseau et al., 1997, Gilbert et al., 2006, Morris et al., 2006, Wang et al., 2011, Skora and Spradling, 2010)
Alleles and Phenotypes
Causes alleles	Meltrin^c768 (Skora and Spradling, 2010) Scer\GAL4^c768 (Manseau et al., 1997, Gilbert et al., 2006, Morris et al., 2006, Wang et al., 2011, Skora and Spradling, 2010)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference embryonic stage \| late embryonic brain (Manseau et al., 1997) presumptive embryonic/larval central nervous system (Manseau et al., 1997) wandering third instar larval stage larval inner optic anlage (Manseau et al., 1997) haltere disc \| restricted (Manseau et al., 1997) ventral nerve cord (Manseau et al., 1997) wing disc \| restricted (Manseau et al., 1997) larval outer optic anlage (Manseau et al., 1997) adult stage oogenesis stage S9 -- S14 follicle cell \| posterior (Manseau et al., 1997)
Additional Information
Statement Reference In third instar larva, expression in wing and haltere discs most pronounced in pouch region. In ovary expressed in all follicle cells overlying oocyte, starting at stage S9. (Manseau et al., 1997)

Marker for
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 2 )
Bloomington	3742 w¹¹¹⁸; P{GawB}Meltrin^c768/TM3, Sb¹ Ser¹
Kyoto	107214 w¹¹¹⁸; P{GawB}Meltrin^c768/TM3, Sb¹ Ser¹
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	c768 (Manseau et al., 1997, Morris et al., 2006) c768-Gal4 (Wang et al., 2011, Skora and Spradling, 2010) c768-GAL4 (Skora and Spradling, 2010) CNS-GAL4 (Gilbert et al., 2006) P{GawB}c768 (Manseau et al., 1997, FlyBase, 1992-) P{GawB}Meltrin^c768 P{GawB}Neu3^c768
Secondary FlyBase IDs

References ( 8 )
Research paper	Wang et al., 2011, Dev. Biol. 350(2): 414--428 Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development. [FBrf0212909] Skora and Spradling, 2010, Proc. Natl. Acad. Sci. U.S.A. 107(16): 7389--7394 Epigenetic stability increases extensively during Drosophila follicle stem cell differentiation. [FBrf0210662] Gilbert et al., 2006, Genetics 173(3): 1365--1375 The Drosophila boundary element-associated factors BEAF-32A and BEAF-32B affect chromatin structure. [FBrf0192350] Morris et al., 2006, PLoS Genet. 2(11): e147 Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo. [FBrf0194141] Manseau et al., 1997, Dev. Dyn. 209(3): 310--322 GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of Drosophila. [FBrf0095642] Brand and Perrimon, 1993, Development 118(2): 401--415 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
Supplementary material	Skora and Spradling, 2010, Proc. Natl. Acad. Sci. U.S.A. 107(16): Supporting Information. [FBrf0215603]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{GawB}Meltrinc768 Insertion

Dmel\P{GawB}Meltrin^c768 Insertion