Dmel\P{GawB}Nup205^179Y Insertion

General Information
Symbol	Dmel\P{GawB}Nup205^179Y	Species	D. melanogaster
Name		FlyBase ID	FBti0004612
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Nup205, Scer\GAL4	Viability / fertility
Causes allele(s)	Nup205^179Y, Scer\GAL4^179Y	Stock availability	2 publicly available
LINE ID
Genomic Location
Chromosomal location	X ( 18F4 )	Sequence location	X:19,747,164..19,747,164
Map ( GBrowse )
Member of Large Scale Dataset(s)
Dataset
Recent Updates
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FB2013_03
FB2013_02
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Detailed Mapping Data
Chromosome (arm)	1 (Matthews, 1998.2.5)
Sequence Location	X:19,747,164..19,747,164 (Skora and Spradling, 2010)
Orientation
Cytological location (computed by FlyBase)	18F4 ( inferred by FlyBase from sequence location )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Nup205 (Skora and Spradling, 2010) Scer\GAL4 (Sage et al., 2008, Manseau et al., 1997, Pereanu et al., 2005, Gunawardena and Goldstein, 2001, Gunawardena et al., 2003, Garg et al., 2007, Rusu et al., 2007, Morris et al., 2006, Skora and Spradling, 2010, Andrenacci et al., 2006, Lorbeck et al., 2011)
Alleles and Phenotypes
Causes alleles	Nup205^179Y (Skora and Spradling, 2010) Scer\GAL4^179Y (Manseau et al., 1997, Pereanu et al., 2005, Gunawardena and Goldstein, 2001, Gunawardena et al., 2003, Sage et al., 2008, Garg et al., 2007, Rusu et al., 2007, Morris et al., 2006, Skora and Spradling, 2010, Andrenacci et al., 2006, Lorbeck et al., 2011)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference embryonic stage \| late organism \| striped (Manseau et al., 1997) larval stage nervous system (Gunawardena and Goldstein, 2001) wandering third instar larval stage embryonic/larval central nervous system (Manseau et al., 1997) adult stage & oogenesis follicle cell (Manseau et al., 1997)
Additional Information
Statement Reference In embryos, late expression in a segmentally repeated pattern of stripes. In the larva, expression in the CNS and the lamina anlagen (near the central brain boundary); no expression observed in eye discs. In ovary, high levels of expression in follicle cells over oocyte. (Manseau et al., 1997)

Marker for
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 2 )
Bloomington	3733 P{GawB}Nup205^179Y, w¹¹¹⁸
Kyoto	107205 P{GawB}Nup205^179Y, w¹¹¹⁸
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	179Y (Manseau et al., 1997, Morris et al., 2006, Skora and Spradling, 2010) 179Y-GAL4 (Gunawardena et al., 2003, Rusu et al., 2007) 179y-GAL4 (Gunawardena and Goldstein, 2001, Rusu et al., 2007, Andrenacci et al., 2006, Lorbeck et al., 2011) 179YGal4 (Garg et al., 2007) 179Y GAL4 (Skora and Spradling, 2010) P{GawB}179Y (Manseau et al., 1997, FlyBase, 1992-, Sage et al., 2008) P{GawB}CG11943^179Y P{GawB}Nup205^179Y
Secondary FlyBase IDs

References ( 15 )
Research paper	Lorbeck et al., 2011, PLoS ONE 6(4): e18412 Microarray analysis uncovers a role for tip60 in nervous system function and general metabolism. [FBrf0213446] Skora and Spradling, 2010, Proc. Natl. Acad. Sci. U.S.A. 107(16): 7389--7394 Epigenetic stability increases extensively during Drosophila follicle stem cell differentiation. [FBrf0210662] Sage et al., 2008, Genetics 178(2): 749--759 Interplay of developmentally regulated gene expression and heterochromatic silencing in trans in Drosophila. [FBrf0204803] Garg et al., 2007, Genetics 175(2): 659--669 Antagonizing scalloped with a novel vestigial construct reveals an important role for scalloped in Drosophila melanogaster leg, eye and optic lobe development. [FBrf0193374] Rusu et al., 2007, Europ. J. Neurosci. 25(4): 1079--1086 Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity. [FBrf0194507] Andrenacci et al., 2006, BMC Genet. 7: 47 Functional dissection of the Drosophila Kallmann's syndrome protein DmKal-1. [FBrf0192789] Morris et al., 2006, PLoS Genet. 2(11): e147 Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo. [FBrf0194141] Pereanu et al., 2005, Dev. Biol. 283(1): 191--203 Morphogenesis and proliferation of the larval brain glia in Drosophila. [FBrf0187395] Gunawardena et al., 2003, Neuron 40(1): 25--40 Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. [FBrf0167960] Gunawardena and Goldstein, 2001, Neuron 32(3): 389--401 Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. [FBrf0141685] Manseau et al., 1997, Dev. Dyn. 209(3): 310--322 GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of Drosophila. [FBrf0095642] Brand and Perrimon, 1993, Development 118(2): 401--415 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
Supplementary material	Skora and Spradling, 2010, Proc. Natl. Acad. Sci. U.S.A. 107(16): Supporting Information. [FBrf0215603]
Personal communication to FlyBase	Matthews, 1998.2.5, Map data for GAL4 enhancer traps. Map data for GAL4 enhancer traps. [FBrf0100404]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{GawB}Nup205179Y Insertion

Dmel\P{GawB}Nup205^179Y Insertion