Dmel\P{lacW}ksr^j5E2 Insertion

General Information
Symbol	Dmel\P{lacW}ksr^j5E2	Species	D. melanogaster
Name		FlyBase ID	FBti0004980
Feature type	transposable_element_insertion_site
Description
Inserted element	P{lacW}	Expression data
Affected gene(s)	Ecol\lacZ, ksr	Viability / fertility
Causes allele(s)	Ecol\lacZ^ksr-j5E2, ksr^j5E2	Stock availability	1 publicly available
LINE ID	l(3)j5E2
Genomic Location
Chromosomal location	3R ( 83A7 )	Sequence location	3R:1,342,878..1,342,878 [+]
Map ( GBrowse )
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
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Detailed Mapping Data
Chromosome (arm)
Sequence Location	3R:1,342,878..1,342,878 [+] (BDGP Project Members, 1994-1999)
Orientation
Cytological location (computed by FlyBase)	83A7 ( inferred by FlyBase from sequence location )
Cytological location (reported)	83A5-83A6 (in situ hybridization reported) (BDGP Project Members, 1994-1999)
Comments concerning location
Sequence Data
Flanking sequence	AQ026325 (FlyBase, 1992-,
Inserted Element
Construct	P{lacW}
Location-dependent role	lacZ enhancer trap (Bier et al., 1989)
Size	10.691Kb
Associated alleles	Ecol\lacZ^P\T.W w^+mC
Molecular map
Affected Gene(s)
Insertion may affect gene	Ecol\lacZ (BDGP Project Members, 1994-1999) ksr (Therrien et al., 1995)
Alleles and Phenotypes
Causes alleles	Ecol\lacZ^ksr-j5E2 (BDGP Project Members, 1994-1999) ksr^j5E2 (Therrien et al., 1995, BDGP Project Members, 1994-1999, Spradling et al., 1999, Dworkin and Gibson, 2006)

Lethality References lethal \| recessive (BDGP Project Members, 1994-1999, Spradling et al., 1999, Dworkin and Gibson, 2006)
Sterility References
Phenotype Manifest In
	wing (Dworkin and Gibson, 2006)
Detailed Description
Statement Reference Heterozygotes show a direct effect on the shape of the wing. (Dworkin and Gibson, 2006)
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID	l(3)j5E2 (Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	10212 w¹¹¹⁸; P{lacW}ksr^j5E2/TM3, P{ftz/lacC}SC1, ry^RK Sb¹ Ser¹
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{lacW}ksr^j5E2 (Sherizen et al., 2005, FlyBase, 1992-) P{lacW}l(3)j5E2^j5E2 (Therrien et al., 1995, FlyBase, 1992-)
Secondary FlyBase IDs

References ( 9 )
Research paper	Dworkin and Gibson, 2006, Genetics 173(3): 1417--1431 Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. [FBrf0193945] Sherizen et al., 2005, Genetics 169(2): 767--781 Meiotic recombination in Drosophila females depends on chromosome continuity between genetically defined boundaries. [FBrf0187659] Bellen et al., 2004, Genetics 167(2): 761--781 The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Therrien et al., 1995, Cell 83(6): 879--888 KSR, a novel protein kinase required for RAS signal transduction. [FBrf0086035] Bier et al., 1989, Genes Dev. 3: 1273--1287 Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. [FBrf0049800]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]

Dmel\P{lacW}ksrj5E2 Insertion

Dmel\P{lacW}ksr^j5E2 Insertion