A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{PZ}fas05488 Insertion

General Information
Symbol Dmel\P{PZ}fas05488 Species D. melanogaster
Name FlyBase ID FBti0005294
Feature type transposable_element_insertion_site
Description
Inserted element P{PZ} Expression data lacZ reporter
Affected gene(s) Ecol\lacZ, fas Viability / fertility
Causes allele(s) Ecol\lacZfas-05488, fas05488 Stock availability 1 publicly available
LINE ID l(2)05488
Genomic Location
Chromosomal location 2R ( 50B4 ) Sequence location 2R:9,480,779..9,480,779 [+]
Map ( GBrowse ) detailed view FBti0048490 FBti0057979 FBti0046743 FBti0049314 FBti0102877 FBti0107565 FBti0055230 FBti0005294 FBti0035508 FBti0111417 FBti0028603 FBti0037172 FBti0059499 FBti0107605 FBti0066181 FBti0045660 FBti0075534 FBti0131843
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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
2R:9,480,779..9,480,779 [+]
(FlyBase, 2005)
Orientation
Cytological location
(computed by FlyBase)
50B4 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
50C1-50C2 (in situ hybridization reported)
(BDGP Project Members, 1994-1999)
Comments concerning
location
hide Sequence Data
Flanking sequence
AQ025638
(FlyBase, 1992-,  
hide Inserted Element
Construct P{PZ}
Location-dependent
role
lacZ enhancer trap
(Mlodzik and Hiromi, 1992)
Size 14.545Kb
Associated alleles
Ecol\lacZP\T.PZ
l(3)87Df7.2
ry+t7.2
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
Ecol\lacZ
(BDGP Project Members, 1994-1999, Jackle and Janning, 1998.8.10, Vosshall, 1998.8.10)
fas
(BDGP Project Members, 1994-1999)
hide Alleles and Phenotypes
Causes alleles
Ecol\lacZfas-05488
(BDGP Project Members, 1994-1999, Jackle and Janning, 1998.8.10, Vosshall, 1998.8.10)
fas05488
(BDGP Project Members, 1994-1999, Jackle and Janning, 1998.8.10, Lekven et al., 1998, Spradling et al., 1999)
Lethality
References
lethal | recessive
(Jackle and Janning, 1998.8.10, Spradling et al., 1999)
Sterility
References
hide Phenotype Manifest In
aCC neuron
(Lekven et al., 1998)
dMP2 neuron
(Lekven et al., 1998)
interface glial cell
(Lekven et al., 1998)
MP1 neuron
(Lekven et al., 1998)
pCC neuron
(Lekven et al., 1998)
vMP2 neuron
(Lekven et al., 1998)
hide Detailed Description
Statement
Reference
Mutant larvae do not have defects in the establishment or maintenance of dendritic tiling in class IV dendrite arborisation (da) neurons.
(Parrish et al., 2007)
Longitudinal glial cells of the central nervous system remain in segmental clusters separated by gaps in homozygous embryos, and remain in a more lateral position than in wild-type. Pioneer neurons (aCC, pCC, vMP2, MP1 and dMP2) develop at abnormal positions and project their axons abnormally; the MP neurons project their axons peripherally instead of longitudinally, and the pCC and aCC neurons project their axons straight laterally instead of longitudinally.
(Lekven et al., 1998)
hide Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
wandering third instar larval stage  
embryonic/larval foregut  
(Meister and Braun, 1995.10)
embryonic/larval midgut  
(Meister and Braun, 1995.10)
Malpighian tubule  
(Meister and Braun, 1995.10)
Additional Information
Statement
Reference
Marker for
Reflects
expression of
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
l(2)05488
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
11411
cn1 P{PZ}fas05488/CyO; ry506
hide Linkouts
hide Comments
Location 2R:9109180-9109181 determined by FlyBase alignment of dbGSS accession AQ025638 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation revised.
(FlyBase, 2005)
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
P141
(Meister and Braun, 1995.10)
P{PZ}fas05488
(FlyBase, 2005, FlyBase, 1992-)
P{PZ}l(2)0548805488
(BDGP Project Members, 1994-1999, FlyBase, 1992-)
P{ry+t7.2=PZ}l(2)0548805488
(FlyBase, 1992-)
Secondary FlyBase IDs
  • FBti0000380
hide References ( 12 )
Research paper
Parrish et al., 2007, Genes Dev. 21(8): 956--972
Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. [FBrf0201136]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
Spradling et al., 1999, Genetics 153(1): 135--177
The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Lekven et al., 1998, Development 125(14): 2747--2758
faint sausage encodes a novel extracellular protein of the immunoglobulin superfamily required for cell migration and the establishment of normal axonal pathways in the Drosophila nervous system. [FBrf0103312]
Mlodzik and Hiromi, 1992, Conn, 1992: 397--414
Enhancer trap method in Drosophila: its application to neurobiology. [FBrf0066714]
Personal communication to FlyBase
Jackle and Janning, 1998.8.10, Patterns of lacZ expression.
Patterns of lacZ expression. [FBrf0103143]
Vosshall, 1998.8.10, Patterns of lacZ expression.
Patterns of lacZ expression. [FBrf0103142]
Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington.
lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714]
FlyBase analysis
FlyBase, 2005, Assessment of transgenic construct insertion sites.
Assessment of transgenic construct insertion sites. [FBrf0184339]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]
BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0067338]