A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{PZ}vlc07022 Insertion

General Information
Symbol Dmel\P{PZ}vlc07022 Species D. melanogaster
Name FlyBase ID FBti0005322
Feature type transposable_element_insertion_site
Description
Inserted element P{PZ} Expression data lacZ reporter
Affected gene(s) Ecol\lacZ, vlc Viability / fertility
Causes allele(s) Ecol\lacZvlc-07022, vlc07022 Stock availability 1 publicly available
LINE ID l(2)07022
Genomic Location
Chromosomal location 2R ( 41F8 ) Sequence location 2R:1,591,197..1,591,197 [+]
Map ( GBrowse ) detailed view FBti0063154 FBti0063157 FBti0063160 FBti0061465 FBti0061466 FBti0063165 FBti0078337 FBti0051979 FBti0026170 FBti0112056 FBti0029752 FBti0039835 FBti0106655 FBti0068596 FBti0103667 FBti0105166 FBti0054535 FBti0104802 FBti0102262 FBti0077978 FBti0046169 FBti0005322 FBti0124965 FBti0044021 FBti0049586 FBti0074801 FBti0053832
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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
2R:1,591,197..1,591,197 [+]
Orientation
Cytological location
(computed by FlyBase)
41F8 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
41F8-41F9 (in situ hybridization reported)
(BDGP Project Members, 1994-1999)
Comments concerning
location
hide Sequence Data
Flanking sequence
G01159
(FlyBase, 1992-,  
hide Inserted Element
Construct P{PZ}
Location-dependent
role
lacZ enhancer trap
(Mlodzik and Hiromi, 1992)
Size 14.545Kb
Associated alleles
Ecol\lacZP\T.PZ
l(3)87Df7.2
ry+t7.2
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
Ecol\lacZ
(BDGP Project Members, 1994-1999, Gates and Thummel, 2000, Jackle and Janning, 1998.8.10, Vosshall, 1998.8.10)
vlc
(BDGP Project Members, 1994-1999)
hide Alleles and Phenotypes
Causes alleles
Ecol\lacZvlc-07022
(BDGP Project Members, 1994-1999, Gates and Thummel, 2000, Jackle and Janning, 1998.8.10, Vosshall, 1998.8.10)
vlc07022
(BDGP Project Members, 1994-1999, Spradling et al., 1999, Gates and Thummel, 2000)
Lethality
References
lethal | recessive
(BDGP Project Members, 1994-1999, Spradling et al., 1999, Gates and Thummel, 2000)
Sterility
References
hide Phenotype Manifest In
leg
(Gates and Thummel, 2000)
metathoracic tarsal segment 2
(Gates and Thummel, 2000)
metathoracic tibia
(Gates and Thummel, 2000)
wing
(Gates and Thummel, 2000)
hide Detailed Description
Statement
Reference
Homozygotes show little or no embryonic lethality. The majority of the lethality occurs during early pupal and pharate adult stages. Homozygous pharate adults have malformed legs, which display a range of phenotypes, including being both short and bent or curved around the edge of the wing. The wings fail to extend as far down the body as the wings of control animals. The tibia and 2nd tarsal segment may contain bends. 14% of mutant mid-prepupae have at least one malformed leg, 27% of mutant pupae and adults have at least one malformed leg.
(Gates and Thummel, 2000)
hide Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage  
ventral thoracic disc  
(Spradling et al., 1999, Gates and Thummel, 2000)
Additional Information
Statement
Reference
Enhancer trap expression is induced by ecdysone in third instar leg imaginal discs.
(Gates and Thummel, 2000)
Marker for
Reflects
expression of
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
l(2)07022
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
12331
cn1 P{PZ}vlc07022/CyO; ry506
hide Linkouts
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
P2331
(Meister and Braun, 1995.10)
P{PZ}l(2)0702207022
(BDGP Project Members, 1994-1999, FlyBase, 1992-)
P{PZ}vlc07022
(FlyBase, 1992-)
P{PZ}vulcan07022
(FlyBase, 1992-)
P{ry+t7.2=PZ}l(2)0702207022
(FlyBase, 1992-)
Secondary FlyBase IDs
  • FBti0000408
hide References ( 10 )
Research paper
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
Gates and Thummel, 2000, Genetics 156(4): 1765--1776
An enhancer trap screen for ecdysone-inducible genes required for Drosophila adult leg morphogenesis. [FBrf0131294]
Spradling et al., 1999, Genetics 153(1): 135--177
The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Mlodzik and Hiromi, 1992, Conn, 1992: 397--414
Enhancer trap method in Drosophila: its application to neurobiology. [FBrf0066714]
Personal communication to FlyBase
Jackle and Janning, 1998.8.10, Patterns of lacZ expression.
Patterns of lacZ expression. [FBrf0103143]
Vosshall, 1998.8.10, Patterns of lacZ expression.
Patterns of lacZ expression. [FBrf0103142]
Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington.
lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714]
FlyBase analysis
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]
BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0067338]