Dmel\P{PZ}Ref1⁰²²⁶⁷ Insertion

General Information
Symbol	Dmel\P{PZ}Ref1⁰²²⁶⁷	Species	D. melanogaster
Name		FlyBase ID	FBti0005452
Feature type	transposable_element_insertion_site
Description
Inserted element	P{PZ}	Expression data	lacZ reporter
Affected gene(s)	Ecol\lacZ, Ref1	Viability / fertility
Causes allele(s)	Ecol\lacZ^Aly-02267, Ref1⁰²²⁶⁷	Stock availability	1 publicly available
LINE ID	l(3)02267
Genomic Location
Chromosomal location	3R ( 84B2 )	Sequence location	3R:2,906,098..2,906,098 [+]
Map ( GBrowse )
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
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Detailed Mapping Data
Chromosome (arm)
Sequence Location	3R:2,906,098..2,906,098 [+] (FlyBase, 2005)
Orientation
Cytological location (computed by FlyBase)	84B2 ( inferred by FlyBase from sequence location )
Cytological location (reported)	84C1-84C2 (in situ hybridization reported) (BDGP Project Members, 1994-1999)
Comments concerning location
Sequence Data
Flanking sequence	AQ026178 (FlyBase, 1992-,
Inserted Element
Construct	P{PZ}
Location-dependent role	lacZ enhancer trap (Mlodzik and Hiromi, 1992)
Size	14.545Kb
Associated alleles	Ecol\lacZ^P\T.PZ l(3)87Df^7.2 ry^+t7.2
Molecular map
Affected Gene(s)
Insertion may affect gene	Ecol\lacZ (BDGP Project Members, 1994-1999, Russell et al., 1998, Vosshall, 1998.8.10, McClure and Schubiger, 2008) Ref1 (BDGP Project Members, 1994-1999, McClure and Schubiger, 2008, Vicente-Crespo et al., 2008)
Alleles and Phenotypes
Causes alleles	Ecol\lacZ^Aly-02267 (BDGP Project Members, 1994-1999, Russell et al., 1998, Vosshall, 1998.8.10, McClure and Schubiger, 2008) Ref1⁰²²⁶⁷ (BDGP Project Members, 1994-1999, Spradling et al., 1999, Beaton, 2000.1.31, McClure and Schubiger, 2008, Vicente-Crespo et al., 2008)

Lethality References lethal \| recessive (BDGP Project Members, 1994-1999, Spradling et al., 1999, Beaton, 2000.1.31)
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference The frequency of leg-to-wing transdetermination caused by expression of wg[Act5C.PS] in clones during the mid-second larval instar is dominantly suppressed by Aly[02267]. (McClure and Schubiger, 2008) A Aly[02267] mutant background suppresses the moderately rough eye phenotype observed upon expression of mbl[C.Scer\UAS] under the control of Scer\GAL4[hs.2sev]. (Vicente-Crespo et al., 2008)
Expression Data
Reporter Expression
distribution deduced from reporter Stage Tissue/Position (including subcellular localization) Reference wandering third instar larval stage imaginal disc (Meister and Braun, 1995.10) embryonic/larval fat body (Meister and Braun, 1995.10)
Additional Information
Statement Reference

Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID	l(3)02267 (Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	11562 P{PZ}Ref1⁰²²⁶⁷ ry⁵⁰⁶/TM3, ry^RK Sb¹ Ser¹
Linkouts
Comments
	Location 3R:2906097-2906098 determined by FlyBase alignment of dbGSS accession AQ026178 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation revised. (FlyBase, 2005)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	Aly⁰²²⁶⁷ (Vicente-Crespo et al., 2008) P{PZ}Aly⁰²²⁶⁷ (FlyBase, 1992-, FlyBase, 2005) P{PZ}l(3)02267⁰²²⁶⁷ (BDGP Project Members, 1994-1999, FlyBase, 1992-) P{PZ}Ref1⁰²²⁶⁷ P{ry^+t7.2=PZ}l(3)02267⁰²²⁶⁷ (FlyBase, 1992-)
Secondary FlyBase IDs
	FBti0000513
References ( 13 )
Research paper	McClure and Schubiger, 2008, Mech. Dev. 125(1-2): 67--80 A screen for genes that function in leg disc regeneration in Drosophila melanogaster. [FBrf0203146] Vicente-Crespo et al., 2008, PLoS ONE 3(2): e1613 Drosophila muscleblind is involved in troponin T alternative splicing and apoptosis. [FBrf0210274] Bellen et al., 2004, Genetics 167(2): 761--781 The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Russell et al., 1998, Genome 41(1): 7--13 Lethal P-lacZ insertion lines expressed during pattern respecification in the imaginal discs of Drosophila. [FBrf0102000] Mlodzik and Hiromi, 1992, Conn, 1992: 397--414 Enhancer trap method in Drosophila: its application to neurobiology. [FBrf0066714]
Personal communication to FlyBase	Beaton, 2000.1.31, BDGP P element Update. BDGP P element Update. [FBrf0126832] Vosshall, 1998.8.10, Patterns of lacZ expression. Patterns of lacZ expression. [FBrf0103142] Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington. lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714]
FlyBase analysis	FlyBase, 2005, Assessment of transgenic construct insertion sites. Assessment of transgenic construct insertion sites. [FBrf0184339] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]

Dmel\P{PZ}Ref102267 Insertion

Dmel\P{PZ}Ref1⁰²²⁶⁷ Insertion