Dmel\P{PZ}l(3)04708⁰⁴⁷⁰⁸ Insertion

General Information
Symbol	Dmel\P{PZ}l(3)04708⁰⁴⁷⁰⁸	Species	D. melanogaster
Name		FlyBase ID	FBti0005517
Feature type	transposable_element_insertion_site
Description
Inserted element	P{PZ}	Expression data	lacZ reporter
Affected gene(s)	Ecol\lacZ, l(3)04708	Viability / fertility
Causes allele(s)	Ecol\lacZ⁰⁴⁷⁰⁸, l(3)04708⁰⁴⁷⁰⁸	Stock availability	1 publicly available
LINE ID	l(3)04708
Genomic Location
Chromosomal location	3R ( 99A1 )	Sequence location	3R:25,040,744..25,040,744 [+]
Map ( GBrowse )
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location	3R:25,040,744..25,040,744 [+] (BDGP Project Members, 1994-1999)
Orientation
Cytological location (computed by FlyBase)	99A1 ( inferred by FlyBase from sequence location )
Cytological location (reported)	99A1-99A2 (in situ hybridization reported) (BDGP Project Members, 1994-1999)
Comments concerning location
Sequence Data
Flanking sequence	AQ034064 (FlyBase, 1992-,
Inserted Element
Construct	P{PZ}
Location-dependent role	lacZ enhancer trap (Mlodzik and Hiromi, 1992)
Size	14.545Kb
Associated alleles	Ecol\lacZ^P\T.PZ l(3)87Df^7.2 ry^+t7.2
Molecular map
Affected Gene(s)
Insertion may affect gene	Ecol\lacZ (BDGP Project Members, 1994-1999, Vosshall, 1998.8.10, Jung et al., 2007) l(3)04708 (BDGP Project Members, 1994-1999)
Alleles and Phenotypes
Causes alleles	Ecol\lacZ⁰⁴⁷⁰⁸ (BDGP Project Members, 1994-1999, Vosshall, 1998.8.10, Jung et al., 2007) l(3)04708⁰⁴⁷⁰⁸ (BDGP Project Members, 1994-1999, Spradling et al., 1999, Maixner et al., 1998)

Lethality References lethal \| recessive (Spradling et al., 1999) semi-lethal
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference The lethality caused by sev^{S11.T:Hsap\MYC} in combination with Ras85D^V12.sev is suppressed by l(3)04708⁰⁴⁷⁰⁸. (Maixner et al., 1998) visible notched wings
Expression Data
Reporter Expression
distribution deduced from reporter Stage Tissue/Position (including subcellular localization) Reference wandering third instar larval stage imaginal disc (Meister and Braun, 1995.10) embryonic/larval fat body (Meister and Braun, 1995.10) gonad (Meister and Braun, 1995.10) embryonic/larval midgut (Meister and Braun, 1995.10) embryonic/larval proventriculus (Meister and Braun, 1995.10)
Additional Information
Statement Reference In third instar larva, highest levels of expression in the proventriculus and the fat body. (Meister and Braun, 1995.10)

Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID	l(3)04708 (Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	11637 ry⁵⁰⁶ P{PZ}l(3)04708⁰⁴⁷⁰⁸/TM3, ry^RK Sb¹ Ser¹
Linkouts
Comments
	Location 3R:25040744-25040745 confirmed by FlyBase alignment of dbGSS accession AQ034064 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. (FlyBase, 2005)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P1637 (Meister and Braun, 1995.10) P{PZ}l(3)04708⁰⁴⁷⁰⁸ (FlyBase, 2005, BDGP Project Members, 1994-1999, FlyBase, 1992-) P{ry^+t7.2=PZ}l(3)04708⁰⁴⁷⁰⁸ (FlyBase, 1992-)
Secondary FlyBase IDs
	FBti0000571
References ( 11 )
Research paper	Jung et al., 2007, J. Cell Sci. 120(16): 2924--2934 The fatty acid elongase NOA is necessary for viability and has a somatic role in Drosophila sperm development. [FBrf0200976] Bellen et al., 2004, Genetics 167(2): 761--781 The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Maixner et al., 1998, Dev. Genet. 23(4): 347--361 A screen for mutations that prevent lethality caused by expression of activated Sevenless and Ras1 in the Drosophila embryo. [FBrf0105879] Mlodzik and Hiromi, 1992, Conn, 1992: 397--414 Enhancer trap method in Drosophila: its application to neurobiology. [FBrf0066714]
Personal communication to FlyBase	Vosshall, 1998.8.10, Patterns of lacZ expression. Patterns of lacZ expression. [FBrf0103142] Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington. lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714]
FlyBase analysis	FlyBase, 2005, Assessment of transgenic construct insertion sites. Assessment of transgenic construct insertion sites. [FBrf0184339] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]

Dmel\P{PZ}l(3)0470804708 Insertion

Dmel\P{PZ}l(3)04708⁰⁴⁷⁰⁸ Insertion