Dmel\P{PZ}aos⁰⁵⁸⁴⁵ Insertion

General Information
Symbol	Dmel\P{PZ}aos⁰⁵⁸⁴⁵	Species	D. melanogaster
Name		FlyBase ID	FBti0005546
Feature type	transposable_element_insertion_site
Description
Inserted element	P{PZ}	Expression data	lacZ reporter
Affected gene(s)	aos, CG33158, Ecol\lacZ	Viability / fertility
Causes allele(s)	aos⁰⁵⁸⁴⁵, CG33158⁰⁵⁸⁴⁵, Ecol\lacZ^aos-05845	Stock availability	1 publicly available
LINE ID	l(3)05845
Genomic Location
Chromosomal location	3L ( 73A2 )	Sequence location	3L:16,476,667..16,476,667 [+]
Map ( GBrowse )
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
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Detailed Mapping Data
Chromosome (arm)
Sequence Location	3L:16,476,667..16,476,667 [+] (BDGP Project Members, 1994-1999)
Orientation
Cytological location (computed by FlyBase)	73A2 ( inferred by FlyBase from sequence location )
Cytological location (reported)	73A1-73A2 (in situ hybridization reported) (BDGP Project Members, 1994-1999)
Comments concerning location
Sequence Data
Flanking sequence	AQ073330 (FlyBase, 1992-,
Inserted Element
Construct	P{PZ}
Location-dependent role	lacZ enhancer trap (Mlodzik and Hiromi, 1992)
Size	14.545Kb
Associated alleles	Ecol\lacZ^P\T.PZ l(3)87Df^7.2 ry^+t7.2
Molecular map
Affected Gene(s)
Insertion may affect gene	aos (Schmucker et al., 1997) CG33158 (FlyBase, 1996-) Ecol\lacZ (BDGP Project Members, 1994-1999, Vosshall, 1998.8.10, Rendina et al., 2010)
Alleles and Phenotypes
Causes alleles	aos⁰⁵⁸⁴⁵ (Schmucker et al., 1997, BDGP Project Members, 1994-1999, Spradling et al., 1999, Voas and Rebay, 2003, FlyBase, 1996-) CG33158⁰⁵⁸⁴⁵ (FlyBase, 1996-) Ecol\lacZ^aos-05845 (BDGP Project Members, 1994-1999, Vosshall, 1998.8.10, Rendina et al., 2010)

Lethality References lethal \| recessive (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Sterility References
Phenotype Manifest In
	Bolwig nerve (Schmucker et al., 1997) Bolwig organ (Schmucker et al., 1997) eye \| posterior (Voas and Rebay, 2003)
Detailed Description
Statement Reference The eye blistering phenotype seen in argos^Δ7/argos⁰⁵⁸⁴⁵ escaper adults is enhanced by rno³/+, so that it covers much of the eye. (Voas and Rebay, 2003) argos^Δ7/argos⁰⁵⁸⁴⁵ escaper adults have extensive blistering along the posterior edge of the eye. (Voas and Rebay, 2003) The cohesion of the Bolwig\'s organ is disrupted and the Bolwig\'s nerve shows defasciculation and misprojection. (Schmucker et al., 1997)
Expression Data
Reporter Expression
distribution deduced from reporter Stage Tissue/Position (including subcellular localization) Reference wandering third instar larval stage imaginal disc (Meister and Braun, 1995.10)
Additional Information
Statement Reference In third instar larva, expression in imaginal discs (which discs not specified). (Meister and Braun, 1995.10)

Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID	l(3)05845 (Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	11674 P{PZ}aos⁰⁵⁸⁴⁵ CG33158⁰⁵⁸⁴⁵ ry⁵⁰⁶/TM3, ry^RK Sb¹ Ser¹
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	aos-lacZ⁰⁵⁸⁴⁵ (Rendina et al., 2010) P1674 (Meister and Braun, 1995.10) P{PZ}aos⁰⁵⁸⁴⁵ P{PZ}argos⁰⁵⁸⁴⁵ (FlyBase, 1992-) P{PZ}gil⁰⁵⁸⁴⁵ (Schmucker et al., 1997, FlyBase, 1992-) P{PZ}l(3)05845⁰⁵⁸⁴⁵ (FlyBase, 1992-) P{ry^+t7.2=PZ}gil⁰⁵⁸⁴⁵ (FlyBase, 1992-)
Secondary FlyBase IDs
	FBti0000233
References ( 12 )
Research paper	Rendina et al., 2010, Genetics 186(1): 167--181 Bap170, a Subunit of the Drosophila PBAP Chromatin Remodeling Complex, Negatively Regulates the EGFR Signaling. [FBrf0211845] Bellen et al., 2004, Genetics 167(2): 761--781 The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132] Voas and Rebay, 2003, Genetics 165(4): 1993--2006 The novel plant homeodomain protein rhinoceros antagonizes Ras signaling in the Drosophila eye. [FBrf0167656] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Schmucker et al., 1997, Development 124(5): 937--948 Genetic analysis of the larval optic nerve projection in Drosophila. [FBrf0092677] Mlodzik and Hiromi, 1992, Conn, 1992: 397--414 Enhancer trap method in Drosophila: its application to neurobiology. [FBrf0066714]
Personal communication to FlyBase	Vosshall, 1998.8.10, Patterns of lacZ expression. Patterns of lacZ expression. [FBrf0103142] Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington. lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]

Dmel\P{PZ}aos05845 Insertion

Dmel\P{PZ}aos⁰⁵⁸⁴⁵ Insertion