Dmel\P{lacW}caps^E2-3-27 Insertion

General Information
Symbol	Dmel\P{lacW}caps^E2-3-27	Species	D. melanogaster
Name		FlyBase ID	FBti0005780
Feature type	transposable_element_insertion_site
Description
Inserted element	P{lacW}	Expression data	lacZ reporter
Affected gene(s)	caps, Ecol\lacZ	Viability / fertility	fertile, viable
Causes allele(s)	caps^E2-3-27, Ecol\lacZ^caps-E2-3-27	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	3L ( 70A3-70A4 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Controlled Vocabulary Terms A1-7 LL1 motor neuron A1-7 ventral motor neuron A1-7 DO2 motor neuron
FB2013_02	Controlled Vocabulary Terms photoreceptor cell R8 third instar larval stage
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	70A3-70A4 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{lacW}
Location-dependent role	lacZ enhancer trap (Bier et al., 1989)
Size	10.691Kb
Associated alleles	Ecol\lacZ^P\T.W w^+mC
Molecular map
Affected Gene(s)
Insertion may affect gene	caps (Shishido et al., 1997) Ecol\lacZ (Morey et al., 2008, Hartenstein and Jan, 1992, Shishido et al., 1997, Lewis and Crews, 1994, Hartenstein and Jan, 1998.8.10, Vosshall, 1998.8.10, Shishido et al., 1998, Krause et al., 2006, Shinza-Kameda et al., 2006)
Alleles and Phenotypes
Causes alleles	caps^E2-3-27 (Shishido et al., 1997, Shishido et al., 1998) Ecol\lacZ^caps-E2-3-27 (Hartenstein and Jan, 1992, Shishido et al., 1997, Morey et al., 2008, Lewis and Crews, 1994, Hartenstein and Jan, 1998.8.10, Vosshall, 1998.8.10, Shishido et al., 1998, Krause et al., 2006, Shinza-Kameda et al., 2006)

Lethality References viable (Jan, 1990.8.1)
Sterility References fertile (Jan, 1990.8.1)
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter Stage Tissue/Position (including subcellular localization) Reference embryonic stage A1-7 ventral oblique muscle 5 (Shishido et al., 1998) histoblast (Hartenstein and Jan, 1998.8.10) A1-7 ventral oblique muscle 3 (Shishido et al., 1998) aCC neuron (Shishido et al., 1998) RP2 motor neuron (Shishido et al., 1998) A1-7 ventral oblique muscle 6 (Shishido et al., 1998) A1-7 dorsal oblique muscle 1 (Shishido et al., 1998) A2-7 dorsal oblique muscle 2 (Shishido et al., 1998) U neuron (Shishido et al., 1998) RP5 motor neuron (Shishido et al., 1998) A1-7 ventral oblique muscle 1 (Shishido et al., 1998) A1-7 ventral longitudinal muscle 1 (Shishido et al., 1998) A1-7 ventral oblique muscle 4 (Shishido et al., 1998) embryonic stage 11 -- 17 ventral nerve cord \| segmentally repeated (Hartenstein and Jan, 1992) embryonic brain \| restricted (Hartenstein and Jan, 1992) embryonic/larval pharynx (Hartenstein and Jan, 1992) inclusive hindgut primordium (Hartenstein and Jan, 1992) embryonic stage 12 -- 17 ventral oblique muscle \| presumptive (Hartenstein and Jan, 1992) peripheral glial cell \| presumptive (Hartenstein and Jan, 1992) dorsal acute muscle \| presumptive (Hartenstein and Jan, 1992) dorsal oblique muscle \| presumptive (Hartenstein and Jan, 1992) third instar larval stage photoreceptor cell R8 (Shinza-Kameda et al., 2006)
Additional Information
Statement Reference Enhancer trap gene expression is observed in four dorsal and 6 ventral muscles. In ventral longitudinal muscle 1, the expression is observed in a single nucleus of the syncytial muscle, near the contact site of the motorneuronal growth cone. Expression is also observed in the CNS in motoneurons aCC, RP2, RP5, and U. (Shishido et al., 1998) In the pharynx, expressed in floor and roof, but not the lateral walls, in the basal cell layer. (Hartenstein and Jan, 1992)

Marker for
Reflects expression of	caps (Shishido et al., 1998)
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	caps-LacZ (Shishido et al., 1998, Morey et al., 2008, Shinza-Kameda et al., 2006) caps-lacZ (Krause et al., 2006) E2-3-27 (Krause et al., 2006) P{lacW}caps^E2-3-27 (Jan, 1990.8.1, FlyBase, 1992-) P{lacW}E2-3-27 (Hartenstein and Jan, 1992, FlyBase, 1992-) P{lacZ}caps¹ (Shishido et al., 1997, FlyBase, 1992-) P{w^+mC=lacW}E2-3-27 (FlyBase, 1992-)
Secondary FlyBase IDs
	FBti0001099 FBti0009714
References ( 12 )
Research paper	Morey et al., 2008, Nature 456(7223): 795--799 Coordinate control of synaptic-layer specificity and rhodopsins in photoreceptor neurons. [FBrf0207285] Krause et al., 2006, Dev. Biol. 296(1): 253--264 Distinct functions of the leucine-rich repeat transmembrane proteins Capricious and Tartan in the Drosophila tracheal morphogenesis. [FBrf0193895] Shinza-Kameda et al., 2006, Neuron 49(2): 205--213 Regulation of layer-specific targeting by reciprocal expression of a cell adhesion molecule, capricious. [FBrf0191328] Shishido et al., 1998, Science 280(5372): 2118--2121 Drosophila synapse formation: regulation by transmembrane protein with leu-rich repeats, CAPRICIOUS. [FBrf0103036] Lewis and Crews, 1994, Mech. Dev. 48(2): 81--91 Genetic analysis of the Drosophila single-minded gene reveals a central nervous system influence on muscle development. [FBrf0078900] Hartenstein and Jan, 1992, Rouxs Arch. Dev. Biol. 201(4): 194--220 Studying Drosophila embryogenesis with P-lacZ enhancer trap lines. [FBrf0057603] Bier et al., 1989, Genes Dev. 3: 1273--1287 Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. [FBrf0049800]
Personal communication to FlyBase	Hartenstein and Jan, 1998.8.10, Patterns of lacZ expression. Patterns of lacZ expression. [FBrf0103138] Vosshall, 1998.8.10, Patterns of lacZ expression. Patterns of lacZ expression. [FBrf0103142] Jan, 1990.8.1, P{lacW} insertions. P{lacW} insertions. [FBrf0122647]
Abstract	Shishido et al., 1997, Stillman, 1997: 195 Capricious, a novel leucine-rich repeat transmembrane protein is involved in neuro-muscular target recognition in Drosophila. [FBrf0100463]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{lacW}capsE2-3-27 Insertion

Dmel\P{lacW}caps^E2-3-27 Insertion