A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Dmel\P{GawB}lilli189Y Insertion

General Information
Symbol Dmel\P{GawB}lilli189Y Species D. melanogaster
Name FlyBase ID FBti0007080
Feature type transposable_element_insertion_site
Description
Inserted element P{GawB} Expression data GAL4 reporter/driver
Affected gene(s) for, lilli, Scer\GAL4 Viability / fertility
Causes allele(s) lilli189Y, Scer\GAL4lilli-189Y Stock availability 1 publicly available
LINE ID
Genomic Location
Chromosomal location 2L ( 24A2-24A4 ) Sequence location
Member of Large Scale Dataset(s)
Dataset
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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location
(computed by FlyBase)
24A2-24A4 ( near gene of known cytology )
Cytological location
(reported)
24A (in situ hybridization reported)
(Renn et al., 1999)
Comments concerning
location
hide Sequence Data
Flanking sequence
hide Inserted Element
Construct P{GawB}
Location-dependent
role
GAL4 driver/enhancer trap
(Brand and Perrimon, 1993)
Size 11.279Kb
Associated alleles
Scer\GAL4wB
w+mW.hs
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
for
(Osborne et al., 1997)
lilli
(Sokolowski, 2006.8.25, Wang et al., 2008)
Scer\GAL4
(Osborne et al., 1997, Renn et al., 1999, Python and Stocker, 2002, Zars et al., 2000, Zars et al., 2000, Shang et al., 2007, Suster et al., 2003, Xiong et al., 2010, Thum et al., 2011, Urizar et al., 2007, Jefferis et al., 2004, Wang et al., 2008, Python and Stocker, 2002, Kong et al., 2010, Chen et al., 2012)
hide Alleles and Phenotypes
Causes alleles
lilli189Y
(Sokolowski, 2006.8.25, Wang et al., 2008)
Scer\GAL4lilli-189Y
(Osborne et al., 1997, Renn et al., 1999, Python and Stocker, 2002, Zars et al., 2000, Zars et al., 2000, Shang et al., 2007, Suster et al., 2003, Xiong et al., 2010, Thum et al., 2011, Urizar et al., 2007, Jefferis et al., 2004, Wang et al., 2008, Python and Stocker, 2002, Kong et al., 2010, Chen et al., 2012)
Lethality
References
Sterility
References
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
Trans-heterozygous for[R] +/+ lilli[189Y] flies show impaired visual pattern memory. Trans-heterozygous for[s] +/+ lilli[189Y] flies show impaired visual pattern memory.
(Wang et al., 2008)
Homozygous lilli[189Y] mutants show impaired visual pattern memory and abnormal foraging behaviour.
(Wang et al., 2008)
hide Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage  
chemosensory neuron | subset  
(Python and Stocker, 2002)
embryonic/larval labral nerve  
(Python and Stocker, 2002)
intrinsic neuron | subset  
(Python and Stocker, 2002)
antennal lobe | restricted  
(Python and Stocker, 2002)
sensory neuron | subset  
(Python and Stocker, 2002)
interneuron | subset  
(Python and Stocker, 2002)
epiphysis | restricted  
(Python and Stocker, 2002)
hypophysis | restricted  
(Python and Stocker, 2002)
embryonic/larval maxillary nerve  
(Python and Stocker, 2002)
interneuron | subset of embryonic/larval antennal lobe  
(Python and Stocker, 2002)
embryonic/larval subesophageal ganglion | restricted  
(Python and Stocker, 2002)
adult stage  
ring neuron R3  
(Chen et al., 2012, Renn et al., 1999)
ellipsoid body  
(Zars et al., 2000)
segmental nerve | restricted  
(Renn et al., 1999)
mushroom body beta-lobe  
(Zars et al., 2000)
pars intercerebralis | restricted  
(Renn et al., 1999)
ellipsoid body | restricted  
(Renn et al., 1999, Urizar et al., 2007)
large field neuron | subset  
(Renn et al., 1999)
mushroom body alpha-lobe  
(Zars et al., 2000)
mushroom body pedunculus  
(Renn et al., 1999)
GABAergic neuron | subset  
(Shang et al., 2007)
cholinergic neuron | subset  
(Shang et al., 2007)
ring neuron R2  
(Urizar et al., 2007)
ring neuron R4m  
(Urizar et al., 2007)
adult mushroom body | restricted  
(Zars et al., 2000)
adult mushroom body gamma-lobe | faint  
(Zars et al., 2000)
Additional Information
Statement
Reference
Local interneurons in which expression is observed are also strongly GABA immunoreactive and negative for serotonin, histamine, and octopamine immunoreactivity.
(Python and Stocker, 2002)
Expression is observed in the ellipsoid body and alpha and beta lobes of the mushroom body, and faintly in the gamma lobe of the mushroom body.
(Zars et al., 2000)
Expression is observed in axons that occupy the inner and medial zones of the ellipsoid body, which enter the ellipsoid body through the canal and arborize throughout much of the ellipsoid body in a manner reminiscent of R3 morphology. Expression is also observed in the mushroom body pedunculus and at the ventral midline of the intersegmental nerve cord.
(Renn et al., 1999)
Marker for
alpha-lobe
(Zars et al., 2000)
beta-lobe
(Zars et al., 2000)
ellipsoid body
(Renn et al., 1999)
labral nerve
(Python and Stocker, 2002)
large field neuron
(Renn et al., 1999)
local interneuron | subset
(Python and Stocker, 2002)
mushroom body
(Zars et al., 2000)
ring neuron R3
(Renn et al., 1999)
Reflects
expression of
for
(Renn et al., 1999, Zars et al., 2000, Python and Stocker, 2002)
Reporter construct
used in assay
Avic\GFPScer\UAS.cYa
(Python and Stocker, 2002)
Avic\GFPScer\UAS.S65T.I167T.T:Btau\MAPT
(Python and Stocker, 2002)
Disc\RFPScer\UAS.cKa
(Chen et al., 2012)
homerScer\UAS.T:Hsap\MYC
(Urizar et al., 2007)
Mmus\Cd8aScer\UAS.T:Avic\GFP
(Shang et al., 2007)
n-sybScer\UAS.cEa.T:Avic\GFP
(Chen et al., 2012)
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
30817
w*; P{GawB}lilli189Y
hide Linkouts
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
189Y
(Zars et al., 2000, Python and Stocker, 2002, Renn et al., 1999, Shang et al., 2007, Suster et al., 2003, Urizar et al., 2007, Python and Stocker, 2002, Kong et al., 2010)
189y
(Zars et al., 2000, Zars et al., 2000, Wang et al., 2008)
189Y-GAL4
(Thum et al., 2011, Chen et al., 2012)
189y-GAL4
(Xiong et al., 2010)
for-189Y
(Osborne et al., 1997)
GAL4-189Y
(Jefferis et al., 2004)
P{GawB}for189Y
(Renn et al., 1999, Osborne et al., 1997, FlyBase, 1992-)
P{GawB}lilli189Y
(FlyBase, 1992-)
Secondary FlyBase IDs
hide References ( 18 )
Research paper
Chen et al., 2012, Dev. Neurobiol. 72(11): 1422--1432
The POU-domain protein Pdm3 regulates axonal targeting of R neurons in the Drosophila ellipsoid body. [FBrf0219674]
Thum et al., 2011, J. Comp. Neurol. 519(17): 3415--3432
Diversity, variability, and suboesophageal connectivity of antennal lobe neurons in D. melanogaster larvae. [FBrf0216269]
Kong et al., 2010, PLoS ONE 5(4): e9954
A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila. [FBrf0210514]
Xiong et al., 2010, Fly 4(3): 194--203
Fixation and locomotor activity are impaired by inducing tetanus toxin expression in adult Drosophila brain. [FBrf0216349]
Wang et al., 2008, Learn. Mem. 15(3): 133--142
Visual pattern memory requires foraging function in the central complex of Drosophila. [FBrf0204617]
Shang et al., 2007, Cell 128(3): 601--612
Excitatory local circuits and their implications for olfactory processing in the fly antennal lobe. [FBrf0192172]
Urizar et al., 2007, J. Neurosci. 27(17): 4541--4551
Drosophila Homer is required in a small set of neurons including the ellipsoid body for normal ethanol sensitivity and tolerance. [FBrf0201158]
Jefferis et al., 2004, Development 131(1): 117--130
Developmental origin of wiring specificity in the olfactory system of Drosophila. [FBrf0167525]
Suster et al., 2003, J. Neurobiol. 55(2): 233--246
Targeted expression of tetanus toxin reveals sets of neurons involved in larval locomotion in Drosophila. [FBrf0159050]
Python and Stocker, 2002, J. Comp. Neurol. 453(2): 157--167
Immunoreactivity against choline acetyltransferase, gamma-aminobutyric acid, histamine, octopamine, and serotonin in the larval chemosensory system of Drosophila melanogaster. [FBrf0152159]
Python and Stocker, 2002, J. Comp. Neurol. 445(4): 374--387
Adult-like complexity of the larval antennal lobe of D. melanogaster despite markedly low numbers of odorant receptor neurons. [FBrf0147119]
Zars et al., 2000, Science 288(5466): 672--675
Localization of a short-term memory in Drosophila. [FBrf0127413]
Zars et al., 2000, Learn. Mem. 7(1): 18--31
Tissue-specific expression of a type I adenylyl cyclase rescues the rutabaga mutant memory defect: in search of the engram. [FBrf0127414]
Renn et al., 1999, J. Neurobiol. 41(2): 189--207
Genetic analysis of the Drosophila ellipsoid body neuropil: Organization and development of the central complex. [FBrf0111476]
Osborne et al., 1997, Science 277(5327): 834--836
Natural behavior polymorphism due to a cGMP-dependent protein kinase of Drosophila. [FBrf0096020]
Brand and Perrimon, 1993, Development 118(2): 401--415
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
Personal communication to FlyBase
Sokolowski, 2006.8.25, 189Y update.
189Y update. [FBrf0198702]
FlyBase analysis
FlyBase, 1992-, FlyBase curation.
FlyBase curation. [FBrf0105495]