Dmel\P{GawB}c747 Insertion

General Information
Symbol	Dmel\P{GawB}c747	Species	D. melanogaster
Name		FlyBase ID	FBti0007258
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Scer\GAL4	Viability / fertility
Causes allele(s)	Scer\GAL4^c747	Stock availability	2 publicly available
LINE ID
Genomic Location
Chromosomal location	2R ( 41F )	Sequence location
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	References Gouzi et al., 2011, PLoS Genet. 7(9): e1002281
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)
Cytological location (reported)	41F (in situ hybridization reported) (Yang et al., 1995)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Scer\GAL4 (Yang et al., 1995, Connolly et al., 1996, Tettamanti et al., 1997, Reeve et al., 2005, Kitamoto, 2002, Rodan et al., 2002, Presente et al., 2004, Astle et al., 2003, DeZazzo et al., 2000, Broughton et al., 2004, McGuire et al., 2003, Waddell et al., 2000, Zars et al., 2000, Zars et al., 2000, Suh et al., 2004, Cheng et al., 2001, Dubnau et al., 2001, Kraft et al., 1998, McGuire et al., 2001, Manseau et al., 1997, Pitman et al., 2006, Joiner et al., 2006, Grammenoudi et al., 2006, Lu et al., 2007, Tzortzopoulos and Skoulakis, 2007, Keleman et al., 2007, Horiuchi et al., 2008, Bolduc et al., 2008, Krashes et al., 2007, Donlea et al., 2009, Schwaerzel et al., 2002, Bates et al., 2010, Liu et al., 2007, Armstrong et al., 1998, Moressis et al., 2009, Hekmat-Scafe et al., 2010, Tamura et al., 2010, Buchanan and Davis, 2010, Ferris et al., 2006, Gouzi et al., 2011)
Alleles and Phenotypes
Causes alleles	Scer\GAL4^c747 (Yang et al., 1995, Connolly et al., 1996, Tettamanti et al., 1997, Reeve et al., 2005, Kitamoto, 2002, Rodan et al., 2002, Presente et al., 2004, Astle et al., 2003, DeZazzo et al., 2000, Broughton et al., 2004, McGuire et al., 2003, Waddell et al., 2000, Zars et al., 2000, Zars et al., 2000, Suh et al., 2004, Cheng et al., 2001, Dubnau et al., 2001, Kraft et al., 1998, McGuire et al., 2001, Manseau et al., 1997, Pitman et al., 2006, Joiner et al., 2006, Grammenoudi et al., 2006, Lu et al., 2007, Tzortzopoulos and Skoulakis, 2007, Keleman et al., 2007, Horiuchi et al., 2008, Bolduc et al., 2008, Krashes et al., 2007, Donlea et al., 2009, Schwaerzel et al., 2002, Bates et al., 2010, Liu et al., 2007, Armstrong et al., 1998, Moressis et al., 2009, Hekmat-Scafe et al., 2010, Tamura et al., 2010, Buchanan and Davis, 2010, Ferris et al., 2006, Gouzi et al., 2011)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference wandering third instar larval stage protocerebral neuromere (Manseau et al., 1997) ventral thoracic disc \| restricted (Manseau et al., 1997) ventral nerve cord (Manseau et al., 1997) wing disc \| restricted (Manseau et al., 1997) pupal stage P7 mushroom body alpha-lobe (Armstrong et al., 1998) mushroom body beta-lobe (Armstrong et al., 1998) mushroom body gamma-lobe (Armstrong et al., 1998) mushroom body alpha'-lobe (Armstrong et al., 1998) Comment:Authors refer to the alpha'-lobe as the 'delta lobe'. adult stage pars intercerebralis (Connolly et al., 1996) Kenyon cell \| subset (Zars et al., 2000) mushroom body pedunculus \| restricted (Zars et al., 2000) thoracico-abdominal ganglion (Connolly et al., 1996) ellipsoid body \| restricted (Zars et al., 2000) mushroom body calyx \| restricted (Zars et al., 2000) mushroom body \| restricted (Zars et al., 2000) median bundle \| restricted (Zars et al., 2000) mushroom body (Connolly et al., 1996) adult brain \| restricted (Connolly et al., 1996) fan-shaped body \| restricted (Zars et al., 2000) antennal lobe glomerulus \| subset (Zars et al., 2000) ring neuron \| subset (Zars et al., 2000) lobe system of mushroom body \| restricted (Zars et al., 2000) adult mushroom body (Dubnau et al., 2001, Waddell et al., 2000) mushroom body alpha-lobe (Krashes et al., 2007, Armstrong et al., 1998) mushroom body beta-lobe (Krashes et al., 2007, Armstrong et al., 1998) mushroom body gamma-lobe (Krashes et al., 2007, Armstrong et al., 1998) mushroom body alpha'-lobe \| restricted (Krashes et al., 2007) mushroom body beta'-lobe \| restricted (Krashes et al., 2007) mushroom body alpha'-lobe (Armstrong et al., 1998) Comment:Authors refer to the alpha'-lobe as the 'delta lobe'. intrinsic neuron of antennal lobe (Armstrong et al., 1998) mushroom body alpha/beta neuron \| subset (Buchanan and Davis, 2010) mushroom body gamma neuron (Buchanan and Davis, 2010) antennal lobe projection neuron \| faint (Buchanan and Davis, 2010) mushroom body alpha'/beta' neuron \| faint (Buchanan and Davis, 2010)
Additional Information
Statement Reference Expression is found in only a few alpha'/beta' neurons. (Krashes et al., 2007) Expression is highest in the mushroom bodies, but is generally widespread. (Waddell et al., 2000) Adult expression is observed weakly in a subset of antennal glomeruli, and more strongly in fibers in the antennomechanosensory tract, subsets of Kenyon cells in the lobes, calyx, and peduncle of the mushroom body, and in the central part of the median bundle. The ellipsoid body is labeled in most domains, possibly from R1 and R4 type ring neurons. A middle layer of the fan-shaped body is faintly labeled from a lateral type large field tangential neuron. Representative images can be seen Figures 4 and 5 of FBrf0127414. (Zars et al., 2000) Scer\GAL4[c747] expresses within a group of neurons connecting the tip of the gamma-lobe to the rostral area of the medial protocerebrum. It also expresses extensively throughout the adult central brain neuropil. (Armstrong et al., 1998) In late third instar larva, expressed in discrete spots in wing and legs discs; expressed in central brain and ventral ganglion. (Manseau et al., 1997) Expression in adult brain primarily in corpora pedunculata (mushroom body). (Connolly et al., 1996)

Marker for	ellipsoid body \| restricted (Zars et al., 2000) Kenyon cell (Zars et al., 2000) median bundle (Zars et al., 2000) mushroom body (Zars et al., 2000) ring neuron <of> ellipsoid body \| subset (Zars et al., 2000)
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 2 )
Bloomington	6494 w^*; P{GawB}c747
Kyoto	108808 w^*; P{GawB}c747
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	747-Gal4 (Bolduc et al., 2008) c747 (Suh et al., 2004, Waddell et al., 2000, Rodan et al., 2002, Manseau et al., 1997, Pitman et al., 2006, Joiner et al., 2006, Horiuchi et al., 2008, Krashes et al., 2007) C747 (Connolly et al., 1996) c747-Gal4 (Tamura et al., 2010, Lu et al., 2007) c747-GAL4 (Bates et al., 2010) c772 (Presente et al., 2004, Rodan et al., 2002, McGuire et al., 2001, Zars et al., 2000, Zars et al., 2000, Grammenoudi et al., 2006, Schwaerzel et al., 2002, Liu et al., 2007, Armstrong et al., 1998, Moressis et al., 2009, Hekmat-Scafe et al., 2010, Ferris et al., 2006) C772 (Donlea et al., 2009) c772Gal4 (Reeve et al., 2005) C772-GAL4 (Astle et al., 2003) c772-GAL4 (Tzortzopoulos and Skoulakis, 2007, Keleman et al., 2007) c772-Gal4 (Liu et al., 2007, Gouzi et al., 2011) c772-gal4 (Buchanan and Davis, 2010) P[GAL4]c772 (Cheng et al., 2001) P{GawB}c747 (Tettamanti et al., 1997, FlyBase, 1992-, ) P{GawB}C747 (FlyBase, 1992-) P{GawB}c772 (FlyBase, 1992-)
Secondary FlyBase IDs
	FBti0002935 FBti0004198
References ( 42 )

Generate a list of	All references relating to this insertion ( 42 )

List References by type	Research paper ( 39 ) Review ( 1 ) FlyBase analysis ( 1 ) Letter ( 1 )
Recent research papers ( 5 )
	Gouzi et al., 2011, PLoS Genet. 7(9): e1002281 The receptor tyrosine kinase alk controls neurofibromin functions in Drosophila growth and learning. [FBrf0216258] Bates et al., 2010, Neural Dev. 5(1): 4 The unfulfilled gene is required for the development of mushroom body neuropil in Drosophila. [FBrf0210102] Buchanan and Davis, 2010, J. Neurosci. 30(30): 10135--10143 A distinct set of Drosophila brain neurons required for neurofibromatosis type 1-dependent learning and memory. [FBrf0211411] Hekmat-Scafe et al., 2010, Genetics 184(1): 171--183 Seizure sensitivity is ameliorated by targeted expression of k+-cl- cotransporter function in the mushroom body of the Drosophila brain. [FBrf0209683] Tamura et al., 2010, J. Neurosci. 30(42): 14091--14101 Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning. [FBrf0212135] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...