A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{EP}skpAEP1423 Insertion

General Information
Symbol Dmel\P{EP}skpAEP1423 Species D. melanogaster
Name FlyBase ID FBti0007441
Feature type transposable_element_insertion_site
Description
Inserted element P{EP} Expression data
Affected gene(s) skpA Viability / fertility
Causes allele(s) skpAEP1423 Stock availability 1 publicly available
LINE ID EP(X)1423
Genomic Location
Chromosomal location X ( 1B14 ) Sequence location X:550,693..550,693 [+]
Map ( GBrowse ) detailed view FBti0063323 FBti0063324 FBti0114780 FBti0018384 FBti0011838 FBti0049798 FBti0039449 FBti0055535 FBti0023358 FBti0034590 FBti0029703 FBti0012828 FBti0015685 FBti0071585 FBti0012840 FBti0029208 FBti0007441 FBti0071247 FBti0052408 FBti0049038 FBti0023210
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Description
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This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
1
(BDGP Project Members, 1994-1999)
Sequence Location
X:550,693..550,693 [+]
(BDGP Project Members, 2000-)
Orientation
Cytological location
(computed by FlyBase)
1B14 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
1B7-1B7 (reported as inferred from sequence location)
(BDGP Project Members, 2000-)
Comments concerning
location
hide Sequence Data
Flanking sequence
AQ025456
(FlyBase, 1992-,  
hide Inserted Element
Construct P{EP}
Location-dependent
role
mobile activating element (UASG)
(Rorth, 1996)
Size 7.987Kb
Associated alleles
Scer\UAS14x.hs
TrlBRcRa
w+mC
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
skpA
(Murphy, 1999.3.10, BDGP Project Members, 2000-)
hide Alleles and Phenotypes
Causes alleles
skpAEP1423
(Murphy, 1999.3.10, Murphy, 2003, Wing et al., 2002, Gene Disruption Project members, 2001-)
Lethality
References
Sterility
References
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
Co-expression of skpAEP1423 enhances the eye phenotype caused by expression of grim::rprrg.Scer\UAS under the control of Scer\GAL4GMR.PF; eye size and/or pigmentation is reduced and the combination shows semi-lethality.
(Wing et al., 2002)
hide Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
EP(X)1423
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
17222
w1118 P{EP}skpAEP1423
hide Linkouts
hide Comments
Location X:513481-513482 confirmed by FlyBase alignment of dbGSS accession AQ025456 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation confirmed.
(FlyBase, 2005)
insertion of mobile activating element
(BDGP Project Members, 1994-1999)
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
ep(x)1423
(FlyBase, 1992-)
EP(X)1423
(FlyBase, 1992-)
P{EP}EP1423
(FlyBase, 1992-)
P{EP}skpAEP1423
(FlyBase, 2005, FlyBase, 1992-)
skpAEP(X)1423
(Murphy, 2003)
Secondary FlyBase IDs
hide References ( 11 )
Research paper
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
Murphy, 2003, J. Cell Sci. 116(11): 2321--2332
Drosophila skpA, a component of SCF ubiquitin ligases, regulates centrosome duplication independently of cyclin E accumulation. [FBrf0159039]
Wing et al., 2002, Nature Cell Biol. 4(6): 451--456
Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis. [FBrf0149135]
Spradling et al., 1999, Genetics 153(1): 135--177
The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Rorth, 1996, Proc. Natl. Acad. Sci. USA 93(22): 12418--12422
A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. [FBrf0090768]
Personal communication to FlyBase
Murphy, 1999.3.10, ADRC-682C.
ADRC-682C. [FBrf0107897]
FlyBase analysis
FlyBase, 2005, Assessment of transgenic construct insertion sites.
Assessment of transgenic construct insertion sites. [FBrf0184339]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0125078]
BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0067338]