Dmel\P{lacZ}Dad^P1883 Insertion

General Information
Symbol	Dmel\P{lacZ}Dad^P1883	Species	D. melanogaster
Name		FlyBase ID	FBti0009617
Feature type	transposable_element_insertion_site
Description
Inserted element	P{lacZ}	Expression data	lacZ reporter
Affected gene(s)	Dad, Ecol\lacZ	Viability / fertility
Causes allele(s)	Dad^P1883, Ecol\lacZ^Dad-P1883	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	3R ( 89E11 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	89E11 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{lacZ}
Location-dependent role	lacZ enhancer trap (FlyBase, 1992-)
Size
Associated alleles
Molecular map
Affected Gene(s)
Insertion may affect gene	Dad (Henderson et al., 1999) Ecol\lacZ (Tsuneizumi et al., 1997, Muzzopappa and Wappner, 2005, Xi et al., 2005, Zhu and Xie, 2003, Rusten et al., 2002, Chen and Schupbach, 2006, Kawase et al., 2004, del Alamo Rodriguez et al., 2004, Torres-Vazquez et al., 2000, Sato and Saigo, 2000, Horsfield et al., 1998, Minami et al., 1999, Christian and Nakayama, 1999, Torres-Vazquez et al., 2001, Xi and Xie, 2005, Stultz et al., 2006, Song et al., 2007, Kirilly et al., 2005, Wada et al., 2007, Shravage et al., 2007, Chau et al., 2009, Shen et al., 2009, Guo and Wang, 2009, Barrio et al., 2007, Liu et al., 2010, Harris et al., 2011, Goldstein et al., 2011, Chen et al., 2010, Liu et al., 2011, Ogiso et al., 2011, Casanueva and Ferguson, 2004, Xia et al., 2010)
Alleles and Phenotypes
Causes alleles	Dad^P1883 (Henderson et al., 1999, Horsfield et al., 1998, Torres-Vazquez et al., 2001) Ecol\lacZ^Dad-P1883 (Tsuneizumi et al., 1997, Muzzopappa and Wappner, 2005, Xi et al., 2005, Zhu and Xie, 2003, Rusten et al., 2002, Chen and Schupbach, 2006, Kawase et al., 2004, del Alamo Rodriguez et al., 2004, Torres-Vazquez et al., 2000, Sato and Saigo, 2000, Horsfield et al., 1998, Minami et al., 1999, Christian and Nakayama, 1999, Torres-Vazquez et al., 2001, Xi and Xie, 2005, Stultz et al., 2006, Song et al., 2007, Kirilly et al., 2005, Wada et al., 2007, Shravage et al., 2007, Chau et al., 2009, Shen et al., 2009, Guo and Wang, 2009, Barrio et al., 2007, Liu et al., 2010, Harris et al., 2011, Goldstein et al., 2011, Chen et al., 2010, Liu et al., 2011, Ogiso et al., 2011, Casanueva and Ferguson, 2004, Xia et al., 2010)

Lethality References lethal \| recessive (Torres-Vazquez et al., 2001)
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference Dad[P1883] partially suppresses the loss of germline stem cells which is seen in the ovarioles of dally[gem] females. (Guo and Wang, 2009)
Expression Data
Reporter Expression
distribution deduced from reporter Stage Tissue/Position (including subcellular localization) Reference embryonic stage (Tsuneizumi et al., 1997) third instar larval stage wing disc \| restricted (Tsuneizumi et al., 1997) oogenesis female germline stem cell (Song et al., 2004) cystoblast \| subset (Song et al., 2004) spermatogenesis male germline stem cell (Kawase et al., 2004) primary gonial cell (Kawase et al., 2004)
Additional Information
Statement Reference Expression pattern of this reporter construct during embryonic and imaginal development resembles that of dpp. (Tsuneizumi et al., 1997)

Marker for	cystoblast (Song et al., 2004) female male germline stem cell (Song et al., 2004) female male germline stem cell cystoblast (Song et al., 2004) male germline stem cell (Kawase et al., 2004) male germline stem cell primary gonial cell (Kawase et al., 2004) primary gonial cell (Kawase et al., 2004)
Reflects expression of	Dad (Song et al., 2004, Kawase et al., 2004)
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	Dad¹⁸⁸³-lacZ (del Alamo Rodriguez et al., 2004) dad^P1883 (Liu et al., 2011) DadlacZ (Song et al., 2004) dad-lacZ (Muzzopappa and Wappner, 2005, Rusten et al., 2002, Sato and Saigo, 2000, Wada et al., 2007, Shravage et al., 2007, Barrio et al., 2007, Goldstein et al., 2011) Dad-lacZ (Song et al., 2004, Kawase et al., 2004, Zhu and Xie, 2003, Xi and Xie, 2005, Stultz et al., 2006, Chen and Schupbach, 2006, Kirilly et al., 2005, Song et al., 2007, Shen et al., 2009, Guo and Wang, 2009, Liu et al., 2010, Harris et al., 2011, Chen et al., 2010) dad-LacZ (Liu et al., 2011) dad-lacZ (P1883) (Ogiso et al., 2011) dad-lacZ¹⁸⁸³ (Liu et al., 2010) P(lacZ) Dad^P1883 (Stultz et al., 2006) P{dad-lacZ} (Chau et al., 2009, Xia et al., 2010) P{lacZ}Dad^P1883 (FlyBase, 1992-) P{lacZ}P1883 (Tsuneizumi et al., 1997, FlyBase, 1992-) PDad^P1883 (Goldstein et al., 2011)
Secondary FlyBase IDs

References ( 35 )

Generate a list of	All references relating to this insertion ( 35 )

List References by type	Research paper ( 33 ) Review ( 1 ) FlyBase analysis ( 1 )
Recent research papers ( 4 )
	Goldstein et al., 2011, Hum. Mol. Genet. 20(5): 894--904 SMAD signaling drives heart and muscle dysfunction in a Drosophila model of muscular dystrophy. [FBrf0212934] Harris et al., 2011, Dev. Cell 20(1): 72--83 Brat Promotes Stem Cell Differentiation via Control of a Bistable Switch that Restricts BMP Signaling. [FBrf0212787] Liu et al., 2011, Dev. Growth Differ. 53(6): 822--841 Negative modulation of bone morphogenetic protein signaling by Dullard during wing vein formation in Drosophila. [FBrf0214664] Ogiso et al., 2011, Dev. Growth Differ. 53(5): 668--678 Robustness of the Dpp morphogen activity gradient depends on negative feedback regulation by the inhibitory Smad, Dad. [FBrf0213936] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...

Dmel\P{lacZ}DadP1883 Insertion

Dmel\P{lacZ}Dad^P1883 Insertion