A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Dmel\P{EP}hiwEP1305 Insertion

General Information
Symbol Dmel\P{EP}hiwEP1305 Species D. melanogaster
Name FlyBase ID FBti0011848
Feature type transposable_element_insertion_site
Description
Inserted element P{EP} Expression data
Affected gene(s) be, hiw Viability / fertility
Causes allele(s) hiwEP1305 Stock availability 1 publicly available
LINE ID EP(X)1305
Genomic Location
Chromosomal location X ( 13A5 ) Sequence location X:14,917,914..14,917,914 [-]
Map ( GBrowse ) detailed view FBti0061119 FBti0061129 FBti0071763 FBti0050555 FBti0070406 FBti0029728 FBti0043154 FBti0035703 FBti0104773 FBti0027219 FBti0037297 FBti0054329 FBti0069355 FBti0056581 FBti0011848 FBti0034750 FBti0037288 FBti0028112 FBti0069826 FBti0057376 FBti0071829 FBti0035748 FBti0068529 FBti0129434 FBti0059200 FBti0056309 FBti0131623 FBti0029355 FBti0033383 FBti0145183
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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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FB2012_01
FB2011_10
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hide Detailed Mapping Data
Chromosome (arm)
Sequence Location
X:14,917,914..14,917,914 [-]
(BDGP Project Members, 2000-)
Orientation
Cytological location
(computed by FlyBase)
13A5 ( inferred by FlyBase from sequence location )
Cytological location
(reported)
13A5-13A6 (in situ hybridization reported)
(BDGP Project Members, 1994-1999)
13A8-13A8 (reported as inferred from sequence location)
(BDGP Project Members, 2000-)
Comments concerning
location
hide Sequence Data
Flanking sequence
AQ073177
(FlyBase, 1992-,  
hide Inserted Element
Construct P{EP}
Location-dependent
role
mobile activating element (UASG)
(Rorth, 1996)
Size 7.987Kb
Associated alleles
Scer\UAS14x.hs
TrlBRcRa
w+mC
Molecular map
hide Affected Gene(s)
Insertion may
affect gene
be
(BDGP Project Members, 2000-)
hiw
(Wan et al., 2000, Gene Disruption Project members, 2001-, Wu et al., 2005)
hide Alleles and Phenotypes
Causes alleles
hiwEP1305
(Wan et al., 2000, Gene Disruption Project members, 2001-, Wu et al., 2005)
Lethality
References
Sterility
References
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
The small eye phenotype caused by co-expression of gigScer\UAS.cTa and Tsc1Scer\UAS.cTa under the control of Scer\GAL4ey.PH is enhanced by hiwEP1305.
(Murthy et al., 2004)
hide Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects
expression of
hide External Images
FlyView (LinkOut)
hide Data on Genetic Line
Line ID
EP(X)1305
(Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 1 )
Bloomington
11420
w1118 P{EP}hiwEP1305
hide Linkouts
hide Comments
Location X:14857818-14857819 confirmed by FlyBase alignment of dbGSS accession AQ073177 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation confirmed.
(FlyBase, 2005)
insertion of mobile activating element
(BDGP Project Members, 1994-1999)
hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
EP(X)1305
(FlyBase, 1992-)
P{EP}EP1305
(FlyBase, 1992-)
P{EP}hiwEP1305
(FlyBase, 2005, FlyBase, 1992-)
PEP1305
(Wu et al., 2005)
Secondary FlyBase IDs
hide References ( 11 )
Research paper
Wu et al., 2005, J. Neurosci. 25(42): 9557--9566
Highwire function at the Drosophila neuromuscular junction: spatial, structural, and temporal requirements. [FBrf0191056]
Bellen et al., 2004, Genetics 167(2): 761--781
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
Murthy et al., 2004, J. Biol. Chem. 279(2): 1351--1358
Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex. [FBrf0167758]
Wan et al., 2000, Neuron 26(2): 313--329
Highwire regulates synaptic growth in Drosophila. [FBrf0128674]
Spradling et al., 1999, Genetics 153(1): 135--177
The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Rorth, 1996, Proc. Natl. Acad. Sci. USA 93(22): 12418--12422
A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. [FBrf0090768]
FlyBase analysis
FlyBase, 2005, Assessment of transgenic construct insertion sites.
Assessment of transgenic construct insertion sites. [FBrf0184339]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]
Computer file
Gene Disruption Project members, 2001-, [title not yet available]
[title not yet available] [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0125078]
BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project.
Berkeley Drosophila Genome Project. [FBrf0067338]