Dmel\P{EP}cv^EP1349 Insertion

General Information
Symbol	Dmel\P{EP}cv^EP1349	Species	D. melanogaster
Name		FlyBase ID	FBti0011887
Feature type	transposable_element_insertion_site
Description
Inserted element	P{EP}	Expression data
Affected gene(s)	CG3160, cv	Viability / fertility
Causes allele(s)	cv^EP1349	Stock availability	1 publicly available
LINE ID	EP(X)1349
Genomic Location
Chromosomal location	X ( 5A13 )	Sequence location	X:5,584,057..5,584,057 [+]
Map ( GBrowse )
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
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Detailed Mapping Data
Chromosome (arm)
Sequence Location	X:5,584,057..5,584,057 [+] (BDGP Project Members, 2000-)
Orientation
Cytological location (computed by FlyBase)	5A13 ( inferred by FlyBase from sequence location )
Cytological location (reported)	5B1-5B1 (reported as inferred from sequence location) (BDGP Project Members, 2000-) 5B1-5B2 (in situ hybridization reported) (BDGP Project Members, 1994-1999)
Comments concerning location
Sequence Data
Flanking sequence	AQ073207 (FlyBase, 1992-,
Inserted Element
Construct	P{EP}
Location-dependent role	mobile activating element (UASG) (Rorth, 1996)
Size	7.987Kb
Associated alleles	Scer\UAS^14x.hs TrlBR^cRa w^+mC
Molecular map
Affected Gene(s)
Insertion may affect gene	CG3160 (BDGP Project Members, 2000-) cv (Tseng and Hariharan, 2002, Shimmi et al., 2005)
Alleles and Phenotypes
Causes alleles	cv^EP1349 (Tseng and Hariharan, 2002, Shimmi et al., 2005)

Lethality References viable (Vilmos, 2005)
Sterility References
Phenotype Manifest In
	eye (Tseng and Hariharan, 2002)
Detailed Description
Statement Reference Co-expression of sog^Scer\UAS.cYa and cv^EP1349 in the posterior compartment of the wing, driven by Scer\GAL4^en-e16E, results in truncation of longitudinal veins in this compartment and the appearance of ectopic veins in the anterior compartment. (Shimmi et al., 2005) Expression of cv^EP1349 under the control of Scer\GAL4^ey.PH results in eyes that are slightly reduced in size. Flies expressing cv^EP1349 under the control of Scer\GAL4^hs.2sev have wild-type eyes. Flies expressing cv^EP1349 under the control of Scer\GAL4^en-e16E have wild-type wings. (Tseng and Hariharan, 2002)
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID	EP(X)1349 (Gene Disruption Project members, 2001-)
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	11237 w¹¹¹⁸ P{EP}cv^EP1349
Linkouts
Comments
	Location X:5535261-5535262 confirmed by FlyBase alignment of dbGSS accession AQ073207 to D. melanogaster arm Release_4 and heterochromatin Release_3.2b. Insertion orientation confirmed. (FlyBase, 2005) insertion of mobile activating element (BDGP Project Members, 1994-1999)
Synonyms & Secondary IDs
Reported As
Symbol Synonym	EP(X)1349 (Shimmi et al., 2005, FlyBase, 1992-) P{EP}cv^EP1349 (FlyBase, 2005, FlyBase, 1992-) P{EP}EP1349 (FlyBase, 1992-)
Secondary FlyBase IDs

References ( 12 )
Research paper	Shimmi et al., 2005, Dev. Biol. 282(1): 70--83 The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing. [FBrf0187398] Bellen et al., 2004, Genetics 167(2): 761--781 The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132] Marcus, 2003, Genetics 163(2): 591--597 Female site-specific transposase-induced recombination: a high-efficiency method for fine mapping mutations on the X chromosome in Drosophila. [FBrf0157240] Tseng and Hariharan, 2002, Genetics 162(1): 229--243 An overexpression screen in Drosophila for genes that restrict growth or cell-cycle progression in the developing eye. [FBrf0152035] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Rorth, 1996, Proc. Natl. Acad. Sci. USA 93(22): 12418--12422 A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. [FBrf0090768]
Supplementary material	Vilmos, 2005, EMBO Rpts 6(3): 1--8 Supplementary Online Material. [FBrf0188586]
FlyBase analysis	FlyBase, 2005, Assessment of transgenic construct insertion sites. Assessment of transgenic construct insertion sites. [FBrf0184339] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078] BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]

Dmel\P{EP}cvEP1349 Insertion

Dmel\P{EP}cv^EP1349 Insertion