Dmel\P{GAL4}sca^P309 Insertion

General Information
Symbol	Dmel\P{GAL4}sca^P309	Species	D. melanogaster
Name		FlyBase ID	FBti0012855
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GAL4}	Expression data	GAL4 reporter/driver
Affected gene(s)	sca, Scer\GAL4	Viability / fertility
Causes allele(s)	sca^P309, Scer\GAL4^sca-P309	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	2R ( 49C3-49D3 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	49C3-49D3 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GAL4}
Location-dependent role	GAL4 driver/enhancer trap (FlyBase, 1992-)
Size
Associated alleles	Scer\GAL4^unspecified
Molecular map
Affected Gene(s)
Insertion may affect gene	sca (Reddy and Rodrigues, 1999) Scer\GAL4 (Reddy and Rodrigues, 1999, Yu et al., 2005, Kanuka et al., 2005, Kanuka et al., 2005, Cai et al., 2003, Yu et al., 2000, Jhaveri et al., 2000, Reddy et al., 1999, Buescher et al., 2004, Sen et al., 2003, Kuranaga et al., 2006, Ishida et al., 2012, Koto et al., 2009, Ayyub et al., 2005)
Alleles and Phenotypes
Causes alleles	sca^P309 (Reddy and Rodrigues, 1999) Scer\GAL4^sca-P309 (Reddy and Rodrigues, 1999, Yu et al., 2005, Kanuka et al., 2005, Kanuka et al., 2005, Cai et al., 2003, Yu et al., 2000, Jhaveri et al., 2000, Reddy et al., 1999, Buescher et al., 2004, Sen et al., 2003, Kuranaga et al., 2006, Ishida et al., 2012, Koto et al., 2009, Ayyub et al., 2005)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference embryonic stage proneural cluster (Reddy and Rodrigues, 1999) larval stage & pupal stage sensory organ cell (Reddy and Rodrigues, 1999) pupal stage external sensory organ precursor cell \| subset (Sen et al., 2003)
Additional Information
Statement Reference Expressed in proneural domains and, subsequently, in all cells comprising a sensory cluster. (Reddy and Rodrigues, 1999)

Marker for
Reflects expression of	sca (Reddy and Rodrigues, 1999)
Reporter construct used in assay	Avic\GFP^{Scer\UAS.T:SV40\nls2} (Sen et al., 2003) N^DN.Scer\UAS (Sen et al., 2003) N^{int.SH.Scer\UAS} (Sen et al., 2003) numb^Scer\UAS.cWa (Sen et al., 2003) pros^Scer\UAS.cMa (Sen et al., 2003) svp^Scer\UAS.cKa (Sen et al., 2003)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P309 (Reddy and Rodrigues, 1999) P{GAL4}sca^P309 (FlyBase, 1992-) Sca^P309-GAL4 (Kuranaga et al., 2006) sca^P309-GAL4 (Koto et al., 2009) scabrous-Gal4^P309 (Sen et al., 2003) sca-gal4 (Yu et al., 2005, Yu et al., 2000) scaGal4 (Buescher et al., 2004) sca-Gal4 (Cai et al., 2003, Ayyub et al., 2005) sca-GAL4 (Ishida et al., 2012) sca-Gal4^P309 (Jhaveri et al., 2000)
Secondary FlyBase IDs

References ( 15 )
Research paper	Ishida et al., 2012, PLoS ONE 7(2): e30265 Prevention of Apoptosis by Mitochondrial Phosphatase PGAM5 in the Mushroom Body Is Crucial for Heat Shock Resistance in Drosophila melanogaster. [FBrf0217492] Koto et al., 2009, J. Cell Biol. 187(2): 219--231 Temporal regulation of Drosophila IAP1 determines caspase functions in sensory organ development. [FBrf0209002] Kuranaga et al., 2006, Cell 126(3): 583--596 Drosophila IKK-related kinase regulates nonapoptotic function of caspases, via degradation of IAPs. [FBrf0194448] Ayyub et al., 2005, Dev. Dyn. 232(3): 865--875 Cullin-5 plays multiple roles in cell fate specification and synapse formation during Drosophila development. [FBrf0183913] Kanuka et al., 2005, EMBO J. 24(21): 3793--3806 Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development. [FBrf0190361] Yu et al., 2005, Genes Dev. 19(11): 1341--1353 Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions. [FBrf0187602] Buescher et al., 2004, Curr. Biol. 14(19): 1694--1702 Drosophila T box proteins break the symmetry of hedgehog-dependent activation of wingless. [FBrf0180065] Cai et al., 2003, Cell 112(1): 51--62 Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. [FBrf0155600] Sen et al., 2003, Dev. Biol. 254(1): 79--92 Combinatorial expression of Prospero, Seven-up, and Elav identifies progenitor cell types during sense-organ differentiation in the Drosophila antenna. [FBrf0158845] Jhaveri et al., 2000, Mech. Dev. 99(1-2): 101--111 Sense organ identity in the Drosophila antenna is specified by the expression of the proneural gene atonal. [FBrf0131324] Yu et al., 2000, Cell 100(4): 399--409 Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization. [FBrf0125333] Reddy and Rodrigues, 1999, Development 126(10): 2083--2092 Sibling cell fate in the Drosophila adult external sense organ lineage is specified by prospero function, which is regulated by Numb and Notch. [FBrf0108429] Reddy et al., 1999, Dev. Genes Evol. 209(10): 581--591 Irregular chiasm-C-roughest, a member of the immunoglobulin superfamily, affects sense organ spacing on the Drosophila antenna by influencing the positioning of founder cells on the disc ectoderm. [FBrf0112065]
Supplementary material	Kanuka et al., 2005, EMBO J. 24(21): Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development. [FBrf0191762]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{GAL4}scaP309 Insertion

Dmel\P{GAL4}sca^P309 Insertion