FlyBase Insertion Report: Dmel\P{GawB}sr[md710]

To study tendon development, sr reporter expression was studied during leg development relative to and odd reporter, which is expressed at the segmental joints. The first tendon to develop is the long tendon of the tarsi that arises from cells coexpressing sr and odd at the T5/pretarsus boundary at early third instar. These cells invaginate and elongate into the tarsal cavity formed by the progressive evagination of the leg disc at the beginning of metamorphosis. By the end of leg development, they will form a long internal tube extending from pre-tarsus to femur with the apical pole facing the lumen. With a short delay, another cluster of tendon precursor cells is specified during the third instar at the femur/tibia boundary in the dorsal position. Subsequently, during early pupation, additional sr-positive clusters are specified along the five segmental pre-patterned odd-positive boundary rings. This indicates that odd/sr-positive tendon precursors are specified progressively following the leg proximodistal segmentation with odd expression preceding sr expression. N was observed to appear sequentially and precede sr expression.

(Laddada et al., 2019)

Drives expression in tendon cells.

(FlyBase Curators, 2017)

Expression is the same as that observed for the sr gene, and does not overlap with the expression pattern of ac or sc.

(Usui et al., 2004)

Larval expression is observed in tendon cells.

(Subramanian et al., 2003)

Pupal expression is observed in the attachment sites of the anterior dorsal medial muscles.

(Ghazi et al., 2000)

Marker for

tendon cell

(Swan et al., 2004, Usui et al., 2004, Subramanian et al., 2003, Ghazi et al., 2000)

Reflects expression of

(Laddada et al., 2019, Inbal et al., 2004, Swan et al., 2004, Usui et al., 2004, Subramanian et al., 2003, Ghazi et al., 2000)

Reporter construct used in assay

Ecol\lacZ^UAS.cUa

(Inbal et al., 2004)

Egfr^DN.UAS

(Inbal et al., 2004)

Avic\GFP^UAS.cUa

(Soler et al., 2004)

Data on Genetic Line

Line ID

Origin as a multiple insertion line

Progenitor(s) within the Genome

Related Aberration or Balancer

Aberration

Balancer

Stocks (1)

Bloomington

26663

w^*; P{GawB}sr^md710/TM6B, Tb¹

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (21)

Reported As

Symbol Synonym

P{GawB}sr^md710

(Bruels et al., 2019, Usui et al., 2004, Ghazi, 2001.1.22, FlyBase, 1992-)

Sr-Gal4

(Moucaud et al., 2024, Laddada et al., 2019)

Sr-Gal4^md710

(Laddada et al., 2019)

Stripe-GAL4

(Uchino et al., 2013)

Stripe-Gal4

(Schulman et al., 2014, van der Plas et al., 2007, Maqbool et al., 2006, Soler et al., 2004)

StripeGal4

(Bharadwaj et al., 2013)

sr-GAL4

(Yoshino et al., 2025, Luedke et al., 2024, Liu et al., 2023, Suver et al., 2023, Ordan et al., 2015, Liu et al., 2013, Lahaye et al., 2012, Loer et al., 2008, Usui-Ishihara and Simpson, 2005)

sr-Gal4

(Chu and Hayashi, 2021, Bataillé et al., 2020, Green et al., 2016, Tiwari et al., 2015, Boukhatmi et al., 2014, Bottenberg et al., 2009, Shalaby et al., 2009, Inbal et al., 2004, Dorfman et al., 2002)

sr-gal4

(Ríos-Barrera et al., 2017, Wayburn and Volk, 2009, Loer et al., 2008, Nabel-Rosen et al., 2002)

sr-gal4^md710

(Moucaud et al., 2024)

sr.GAL4

(Saavedra et al., 2014)

sr.Gal4

(Saavedra et al., 2016, Krzemien et al., 2012)

sr^MD710-GAL4

(Pissarek et al., 2025)

srGAL4

(Ghazi, 2001.1.22, Ghazi et al., 2000)

srGal4

(Pérez-Moreno et al., 2017, Butí et al., 2014)

sr[MD710]-Gal4

(Usui et al., 2004)

srmd710-GAL4

(Coni et al., 2021)

stripe-GAL4

(Pissarek et al., 2025, Zhang et al., 2024, Takayanagi-Kiya et al., 2023, Lemke et al., 2019, Pérez-Moreno et al., 2017, Ordan et al., 2015, Nir et al., 2012, Schnorrer et al., 2007, Swan et al., 2004, Subramanian et al., 2003)

stripe-Gal4

(Hudry et al., 2016, Wang et al., 2015, Alves-Silva et al., 2012)

stripe-gal4

(Gilsohn and Volk, 2010, Subramanian et al., 2007, Soustelle et al., 2004, Swan et al., 2004, Subramanian et al., 2003)

stripe^MD710-Gal4

(Shalaby et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (56)

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