Dmel\P{GawB}SG18.1 Insertion

General Information
Symbol	Dmel\P{GawB}SG18.1	Species	D. melanogaster
Name		FlyBase ID	FBti0017057
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Scer\GAL4	Viability / fertility
Causes allele(s)	Scer\GAL4^SG18.1	Stock availability	2 publicly available
LINE ID
Genomic Location
Chromosomal location	2R ( 57A )	Sequence location
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)
Cytological location (reported)	57A (in situ hybridization reported) (Shyamala and Chopra, 1999)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Scer\GAL4 (Jhaveri et al., 2000, Bhalerao et al., 2003, Jhaveri and Rodrigues, 2002, Manoli et al., 2005, Ang et al., 2003, Hummel and Zipursky, 2004, Jhaveri et al., 2004, Shyamala and Chopra, 1999, Sarpal et al., 2003, Ang et al., 2006, Sakurai et al., 2009, Boltz et al., 2007)
Alleles and Phenotypes
Causes alleles	Scer\GAL4^SG18.1 (Jhaveri et al., 2000, Bhalerao et al., 2003, Jhaveri and Rodrigues, 2002, Manoli et al., 2005, Ang et al., 2003, Hummel and Zipursky, 2004, Jhaveri et al., 2004, Shyamala and Chopra, 1999, Sarpal et al., 2003, Ang et al., 2006, Sakurai et al., 2009, Boltz et al., 2007)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference embryonic stage 13 -- 17 sensory neuron (Shyamala and Chopra, 1999) larval stage haltere disc \| restricted (Shyamala and Chopra, 1999) ventral thoracic disc \| restricted (Shyamala and Chopra, 1999) wing disc \| restricted (Shyamala and Chopra, 1999) larval stage -- adult stage sensory neuron \| subset (Sarpal et al., 2003) central nervous system \| subset (Sarpal et al., 2003) third instar larval stage eye-antennal disc \| restricted (Shyamala and Chopra, 1999) P-stage olfactory receptor neuron \| subset (Hummel and Zipursky, 2004) pupal stage sensory neuron of antenna (Shyamala and Chopra, 1999) Comment:>=57 hr pupal stage P6 antenna (Ang et al., 2003) Comment:reference states 30 hr APF olfactory receptor neuron (Ang et al., 2003) Comment:reference states 30 hr APF pharate adult stage P8 antennal lobe glomerulus (Jhaveri and Rodrigues, 2002) Comment:>=48 hr APF pharate adult stage P9 -- P15 antenna \| restricted (Shyamala and Chopra, 1999) Comment:reference states >=57 hr APF antennal nerve (Shyamala and Chopra, 1999) Comment:reference states >=57 hr APF sensory neuron \| subset (Shyamala and Chopra, 1999) Comment:reference states >=57 hr APF adult stage adult antennal lobe projection neuron of mushroom body calyx (Shyamala and Chopra, 1999) antennal nerve (Jhaveri et al., 2004, Shyamala and Chopra, 1999) sensillum trichodeum of antennal segment 3 (Jhaveri and Rodrigues, 2002) antennal lobe \| restricted (Shyamala and Chopra, 1999) nerve terminal of olfactory receptor neuron (Jhaveri et al., 2004) antennal lobe glomerulus (Jhaveri et al., 2004, Shyamala and Chopra, 1999, Ang et al., 2003) third segment of antenna (Shyamala and Chopra, 1999) sensory neuron \| subset (Shyamala and Chopra, 1999) nerve terminal \| subset (Jhaveri et al., 2004) adult antennal lobe projection neuron \| subset (Shyamala and Chopra, 1999) mushroom body calyx (Shyamala and Chopra, 1999) mushroom body calyx \| restricted (Shyamala and Chopra, 1999) olfactory receptor neuron (Jhaveri and Rodrigues, 2002) adult antennal lobe projection neuron of antennal lobe (Shyamala and Chopra, 1999) sensory neuron of maxillary palpus (Shyamala and Chopra, 1999) antennal lobe (Jhaveri et al., 2004, Shyamala and Chopra, 1999, Jhaveri and Rodrigues, 2002, Ang et al., 2003) olfactory receptor neuron \| restricted (Jhaveri et al., 2004) sensillum basiconicum of antennal segment 3 (Jhaveri and Rodrigues, 2002) maxillary palpus \| restricted (Shyamala and Chopra, 1999) sensillum coeloconicum of antennal segment 3 (Jhaveri and Rodrigues, 2002)
Additional Information
Statement Reference In early pupal development, expression is observed in most, but not all, olfactory neurons, particularly in early projecting olfactory neurons. (Hummel and Zipursky, 2004) Adult expression reveals that olfactory neuron sensory arbors are located in a `doughnut-like' arrangement on the periphery of the glomerulus. (Jhaveri et al., 2004) Pupal expression is observed in cells with bipolar morphology typical of olfactory neurons. Adult expression is observed in the outer nerve layer of the antennal lobes, and in many antennal glomeruli. (Ang et al., 2003) Expression is observed in a majority of sensory neurons plus a subset of neurons in the central nervous system in larvae and adults. (Sarpal et al., 2003) Adult expression is observed in olfactory sensory neurons of the third antennal segment, with stronger expression in the coeloconic and trichoid sense organs. (Jhaveri and Rodrigues, 2002) Larval expression is observed in a ring pattern on the leg disc, in the dorsal and ventral wing blade region of the wing disc, and in the dorsal and ventral surfaces of the haltere disc. In the third instar, expression is observed in clusters of cells in presumptive antennal segment 3, and in the maxillary palpus region. Pupal expression observed in antennal sensory neurons and in the antennal nerve. Adult expression is observed in the olfactory receptors and the CNS processing centers of the olfactory receptors, specifically in sensory neurons of antennal segment 3 and the maxillary palpus, afferents from those sensilla projecting into the antennal lobe, their interneurons, relay interneurons from the antennal glomeruli to the calyx of the mushroom body, and the calyx of the mushroom body. (Shyamala and Chopra, 1999)

Marker for	antennal glomerulus (Shyamala and Chopra, 1999, Jhaveri et al., 2004) antennal lobe (Ang et al., 2003, Shyamala and Chopra, 1999) calyx of mushroom body (Shyamala and Chopra, 1999) olfactory neuron (Jhaveri and Rodrigues, 2002) olfactory neuron antennal lobe (Ang et al., 2003) olfactory neuron terminal (Jhaveri et al., 2004) sensory neuron (Jhaveri and Rodrigues, 2002, Sarpal et al., 2003)
Reflects expression of
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 2 )
Bloomington	6405 w^*; P{GawB}SG18.1
Kyoto	108770 w^*; P{GawB}SG18.1
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	Gal4-SG18.1 (Jhaveri et al., 2000) Gal^SG18.1 (Sarpal et al., 2003) P{GAL4}SG18 (Jhaveri et al., 2000, FlyBase, 1992-) P{GawB}SG18.1 (FlyBase, 1992-) SG18.1 (Shyamala and Chopra, 1999, Sakurai et al., 2009) SG18.1-Gal4 (Sarpal et al., 2003, Hummel and Zipursky, 2004, Jhaveri et al., 2004, Bhalerao et al., 2003, Ang et al., 2003, Jhaveri and Rodrigues, 2002, Ang et al., 2006) SG18.1-GAL4 (Manoli et al., 2005, Boltz et al., 2007)
Secondary FlyBase IDs

References ( 15 )
Research paper	Sakurai et al., 2009, J. Neurosci. 29(15): 4972--4980 Differentially expressed Drl and Drl-2 play opposing roles in Wnt5 signaling during Drosophila olfactory system development. [FBrf0207647] Boltz et al., 2007, Dev. Dynamics 236(2): 544--555 Drosophila melanogaster p24 genes have developmental, tissue-specific, and sex-specific expression patterns and functions. [FBrf0195392] Ang et al., 2006, Dev. Biol. 293(1): 178--190 Lim kinase regulates the development of olfactory and neuromuscular synapses. [FBrf0190083] Manoli et al., 2005, Nature 436(7049): 395--400 Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour. [FBrf0188142] Hummel and Zipursky, 2004, Neuron 42(1): 77--88 Afferent induction of olfactory glomeruli requires N-cadherin. [FBrf0175028] Jhaveri et al., 2004, Development 131(9): 1903--1912 Positioning sensory terminals in the olfactory lobe of Drosophila by Robo signaling. [FBrf0174568] Ang et al., 2003, Development 130(7): 1307--1316 Dock and Pak regulate olfactory axon pathfinding in Drosophila. [FBrf0155701] Bhalerao et al., 2003, J. Neurobiol. 54(4): 577--592 Olfactory neurons expressing identified receptor genes project to subsets of glomeruli within the antennal lobe of Drosophila melanogaster. [FBrf0155888] Sarpal et al., 2003, Curr. Biol. 13(19): 1687--1696 Drosophila KAP interacts with the kinesin II motor subunit KLP64D to assemble chordotonal sensory cilia, but not sperm tails. [FBrf0167402] Jhaveri and Rodrigues, 2002, Development 129(5): 1251--1260 Sensory neurons of the Atonal lineage pioneer the formation of glomeruli within the adult Drosophila olfactory lobe. [FBrf0144822] Jhaveri et al., 2000, Mech. Dev. 99(1-2): 101--111 Sense organ identity in the Drosophila antenna is specified by the expression of the proneural gene atonal. [FBrf0131324] Shyamala and Chopra, 1999, J. Genet. 78(2): 87--97 Drosophila melanogaster chemosensory and muscle development: identification and properties of a novel allele of scalloped and of a new locus, SG18.1, in a Gal4 enhancer trap screen. [FBrf0127327] Brand and Perrimon, 1993, Development 118(2): 401--415 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
Personal communication to FlyBase	Ayyub, 2001.12.14, P{GawB}neur<up>GAL4-A101</up>. P{GawB}neur^GAL4-A101. [FBrf0145596]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]