Dmel\P{GawB}l(2)Mai179^Mai179 Insertion

General Information
Symbol	Dmel\P{GawB}l(2)Mai179^Mai179	Species	D. melanogaster
Name		FlyBase ID	FBti0017959
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	l(2)Mai179, Scer\GAL4	Viability / fertility
Causes allele(s)	l(2)Mai179^Mai179, Scer\GAL4^Mai179	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	2L ( 33E3--33E7 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)
Cytological location (reported)	33E3--33E7 (in situ hybridization reported) (Siegmund and Korge, 2001)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	l(2)Mai179 (Siegmund and Korge, 2001) Scer\GAL4 (Picot et al., 2007, Yoshii et al., 2008, Siegmund and Korge, 2001, Rodan et al., 2002, Grima et al., 2004, Johard et al., 2009, Rieger et al., 2009, Shafer and Taghert, 2009, Lear et al., 2005, Nässel et al., 2008, Sundram et al., 2012, Duvall and Taghert, 2012)
Alleles and Phenotypes
Causes alleles	l(2)Mai179^Mai179 (Siegmund and Korge, 2001) Scer\GAL4^Mai179 (Siegmund and Korge, 2001, Rodan et al., 2002, Picot et al., 2007, Grima et al., 2004, Yoshii et al., 2008, Johard et al., 2009, Rieger et al., 2009, Shafer and Taghert, 2009, Lear et al., 2005, Nässel et al., 2008, Sundram et al., 2012, Duvall and Taghert, 2012)

Lethality References lethal \| recessive (Siegmund and Korge, 2001)
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference larval stage prothoracic gland innervating neuron PG-LP (Siegmund and Korge, 2001) corpus allatum innervating neuron CA-LP 1 (Siegmund and Korge, 2001) corpus allatum innervating neuron CA-LP 2 (Siegmund and Korge, 2001) corpus cardiacum innervating neuron CC/A-PI 2 (Siegmund and Korge, 2001) corpus cardiacum innervating neuron CC-MS 1 (Siegmund and Korge, 2001) corpus cardiacum innervating neuron CC-MS 2 (Siegmund and Korge, 2001) larval s-LNv Pdf neuron (Siegmund and Korge, 2001) adult stage neurosecretory cell \| subset (Nässel et al., 2008) interneuron of adult pars intercerebralis (Nässel et al., 2008) LNd neuron \| subset (Yoshii et al., 2008) s-LNv neuron (Shafer and Taghert, 2009) l-LNv neuron \| subset (Shafer and Taghert, 2009)
Additional Information
Statement Reference Scer\GAL4[Mai179] is expressed in one or two of the l-LNv neurons. (Shafer and Taghert, 2009) Expression of Scer\GAL4[Mai179] is seen in three of the LNd neuronal cluster cells. (Yoshii et al., 2008)

Marker for
Reflects expression of
Reporter construct used in assay	Avic\GFP^{S65T.Scer\UAS} (Yoshii et al., 2008) Dcr-2^Scer\UAS.cDa (Shafer and Taghert, 2009) Ecol\lacZ^{Scer\UAS.T:Btau\MAPT} (Siegmund and Korge, 2001) Ecol\lacZ^{Scer\UAS.T:SV40\nls2} (Shafer and Taghert, 2009) Mmus\Cd8a^{Scer\UAS.T:Avic\GFP} (Nässel et al., 2008) Pdf^GD299 (Shafer and Taghert, 2009)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome
Transposed descendant of	P{GawB}l(1)BP¹
Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	Mai179 (Rodan et al., 2002) mai179 (Sundram et al., 2012) mai179G4 (Sundram et al., 2012) Mai179-Gal4 (Grima et al., 2004, Picot et al., 2007, Shafer and Taghert, 2009, Nässel et al., 2008, Johard et al., 2009) Mai179-gal4 (Rieger et al., 2009, Yoshii et al., 2008, Duvall and Taghert, 2012) Mai179-GAL4 (Lear et al., 2005) Mai 179P{GawB}33E3-7 (Siegmund and Korge, 2001) P{GawB}l(2)Mai179^Mai179 (FlyBase, 1992-)
Secondary FlyBase IDs

References ( 14 )
Research paper	Duvall and Taghert, 2012, PLoS Biol. 10(6): e1001337 The Circadian Neuropeptide PDF Signals Preferentially through a Specific Adenylate Cyclase Isoform AC3 in M Pacemakers of Drosophila. [FBrf0218594] Sundram et al., 2012, J. Biol. Rhythms 27(3): 183--195 Cellular Requirements for LARK in the Drosophila Circadian System. [FBrf0218481] Johard et al., 2009, J. Comp. Neurol. 516(1): 59--73 Peptidergic clock neurons in Drosophila: ion transport peptide and short neuropeptide F in subsets of dorsal and ventral lateral neurons. [FBrf0208477] Rieger et al., 2009, J. Biol. Rhythms 24(4): 271--282 Period Gene Expression in Four Neurons Is Sufficient for Rhythmic Activity of Drosophila melanogaster under Dim Light Conditions. [FBrf0208345] Shafer and Taghert, 2009, PLoS ONE 4(12): e8298 RNA-Interference Knockdown of Drosophila Pigment Dispersing Factor in Neuronal Subsets: The Anatomical Basis of a Neuropeptide's Circadian Functions. [FBrf0209505] Nässel et al., 2008, BMC Neurosci. 9: 90 A large population of diverse neurons in the Drosophila central nervous system expresses short neuropeptide F, suggesting multiple distributed peptide functions. [FBrf0206024] Yoshii et al., 2008, J. Comp. Neurol. 508(6): 952--966 Cryptochrome is present in the compound eyes and a subset of Drosophila's clock neurons. [FBrf0205220] Picot et al., 2007, PLoS Biol. 5(11): e315 Light activates output from evening neurons and inhibits output from morning neurons in the Drosophila circadian clock. [FBrf0202589] Lear et al., 2005, Neuron 48(6): 965--976 The ion channel narrow abdomen is critical for neural output of the Drosophila circadian pacemaker. [FBrf0191323] Grima et al., 2004, Nature 431(7010): 869--873 Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain. [FBrf0179741] Rodan et al., 2002, J. Neurosci. 22(21): 9490--9501 Functional dissection of neuroanatomical loci regulating ethanol sensitivity in Drosophila. [FBrf0152149] Siegmund and Korge, 2001, J. Comp. Neurol. 431(4): 481--491 Innervation of the ring gland of Drosophila melanogaster. [FBrf0134726] Brand and Perrimon, 1993, Development 118(2): 401--415 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{GawB}l(2)Mai179Mai179 Insertion

Dmel\P{GawB}l(2)Mai179^Mai179 Insertion