Dmel\P{3'EP}JIL-1^z60 Insertion

General Information
Symbol	Dmel\P{3'EP}JIL-1^z60	Species	D. melanogaster
Name		FlyBase ID	FBti0018033
Feature type	transposable_element_insertion_site
Description
Inserted element	P{3'EP}	Expression data
Affected gene(s)	JIL-1	Viability / fertility
Causes allele(s)	JIL-1^z60	Stock availability	none publicly available
LINE ID
Genomic Location
Chromosomal location	3L ( 68A5-68A6 )	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
Chromosome (arm)
Sequence Location
Orientation
Cytological location (computed by FlyBase)	68A5-68A6 ( near gene of known cytology )
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{3'EP}
Location-dependent role
Size
Associated alleles
Molecular map
Affected Gene(s)
Insertion may affect gene	JIL-1 (Wang et al., 2001)
Alleles and Phenotypes
Causes alleles	JIL-1^z60 (Wang et al., 2001, Zhang et al., 2006, Zhang et al., 2003)

Lethality References lethal (Zhang et al., 2006) lethal \| recessive (Wang et al., 2001, Wang et al., 2001) partially lethal - majority die (Lerach et al., 2006, Bao et al., 2007)
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference JIL-1^z2/JIL-1^z60 flies that have one copy of the Su(var)3-9¹ allele show greater levels of survival compared to those that carry two wild-type copies of Su(var)3-9. (Zhang et al., 2006) Only 1 out of 871 JIL-1^z2/JIL-1^z60 flies eclose. (Zhang et al., 2006) Eclosion rate is less than 3%. (Wang et al., 2001) Homozygous larvae have an eclosion rate of 0.5%. The number of males eclosing is 32% that of females. The polytene chromosome banding pattern is perturbed in homozygous third instar larvae. Perturbation of the male X chromosome is relatively more severe than that of the autosomes. (Wang et al., 2001)
Expression Data
Reporter Expression

Additional Information
Statement Reference

Marker for
Reflects expression of
Reporter construct used in assay
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome
Modified descendant of	P{EP}JIL-1^EP3657 (Zhang et al., 2003)
Related Aberration or Balancer
Aberration
Balancer
Stocks ( 0 )

Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	P{3''EP}JIL-1^z60 (Wang et al., 2001) P{3'EP}JIL-1^z60 (FlyBase, 1992-)
Secondary FlyBase IDs

References ( 7 )
Research paper	Bao et al., 2007, Genetics 176(2): 1355--1358 Loss-of-function alleles of the JIL-1 histone H3S10 kinase enhance position-effect variegation at pericentric sites in Drosophila heterochromatin. [FBrf0202093] Lerach et al., 2006, Genetics 173(4): 2403--2406 Loss-of-function alleles of the JIL-1 kinase are strong suppressors of position effect variegation of the wm4 allele in Drosophila. [FBrf0192731] Zhang et al., 2006, Development 133(2): 229--235 The JIL-1 histone H3S10 kinase regulates dimethyl H3K9 modifications and heterochromatic spreading in Drosophila. [FBrf0190333] Zhang et al., 2003, Genetics 165(3): 1341--1354 Genetic and phenotypic analysis of alleles of the Drosophila chromosomal JIL-1 kinase reveals a functional requirement at multiple developmental stages. [FBrf0167636] Wang et al., 2001, Cell 105(4): 433--443 The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila. [FBrf0136815]
Abstract	Wang et al., 2001, A. Dros. Res. Conf. 42: 38 JIL-1, a putative chromosomal histone H3 kinase, is required for maintenance of chromatin structure. [FBrf0133755]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]

Dmel\P{3'EP}JIL-1z60 Insertion

Dmel\P{3'EP}JIL-1^z60 Insertion